HRT Patches vs. Pills: Which Is More Effective?
When it comes to managing menopause symptoms, many women turn to hormone replacement therapy (HRT). The decision between using HRT patches or pills often confuses those looking to alleviate their symptoms. Both methods have their own benefits and drawbacks, and the right choice can depend on your preferences, lifestyle, and medical needs. In this article, we’ll break down the differences between HRT patches and pills, and help you understand which might be more effective for you.
What Is Hormone Replacement Therapy (HRT)?
Hormone replacement therapy (HRT) is commonly used to manage symptoms associated with menopause, such as vaginal dryness, mood swings, hot flushes and night sweats. During menopause, the ovaries stop producing eggs and significantly reduce the production of hormones, particularly oestrogen and progesterone. HRT helps to replace these hormones, providing relief from the disruptive symptoms.
HRT Pills: Convenient and Traditional
HRT pills are one of the most common ways to deliver hormones to the body. These tablets contain synthetic versions of oestrogen (and sometimes progesterone), which are absorbed through the digestive system and into the bloodstream.
Advantages of HRT Pills
- Easy to Use: HRT pills are simple to take, usually once a day, which fits easily into a daily routine.
- Availability: They are widely available and come in a variety of options, making it easier to find a prescription that suits your needs.
- Proven Effectiveness: Many women have used HRT pills for years with great success, so they are a well-tested and trusted option for managing menopause symptoms.
Disadvantages of HRT Pills
- Digestive System Impact: Since the medication must pass through your digestive system, some women experience side effects such as nausea, stomach cramps, or bloating.
- Higher Risk of Blood Clots: There is an increased risk of blood clots with HRT pills, especially for women who smoke or have pre-existing health conditions. This risk is particularly high for those who use combined HRT (oestrogen and progesterone).
- Fluctuating Levels: Pills can cause fluctuations in hormone levels because the hormones are absorbed all at once when taken. This can lead to periods of hormone surges and dips, which may cause irregular side effects.
Elleste Duet Tablets are a popular choice among those looking for HRT pills. This medication combines two types of hormones, helping to ease menopausal symptoms. It is known for its effectiveness in managing hot flashes, night sweats, and mood swings.
HRT Patches: Convenient and Steady Hormone Release
HRT patches, such as Estraderm MX Patches and Evorel Patches, are an alternative to pills. These patches deliver hormones directly through the skin, bypassing the digestive system. The active ingredients are absorbed through the skin and into the bloodstream at a steady, consistent rate.
Advantages of HRT Patches
- Steady Hormone Release: Since the hormones are released gradually, patches provide a more consistent level of hormones in the bloodstream. This helps avoid the ups and downs that can happen with pills.
- Less Impact on the Digestive System: With patches, there’s no need for the hormone to pass through the digestive system, so women who have sensitive stomachs or are prone to nausea may prefer them.
- Convenience: Patches are typically worn for several days before needing to be replaced, making them less of a daily hassle than pills.
- Lower Risk of Blood Clots: Since the hormone is absorbed through the skin, there is a reduced risk of blood clots compared to oral HRT, particularly for women who are at higher risk.
Disadvantages of HRT Patches
Skin Irritation: Some women may experience skin irritation when the patch is applied. Redness, itching, or rashes can occur, though this is generally not common.
Adhesion Issues: Patches may not stick well in humid conditions or during activities that cause sweating, which may require women to replace them more often.
Visibility: Unlike pills, which are discreet, patches can be visible if worn on certain parts of the body. Some women may not be comfortable with this.
Estraderm MX Patches and Evorel Patches are both excellent choices for those who prefer a patch. These patches provide consistent, long-lasting relief and are ideal for women who want convenience without daily pill-taking.
Which Is More Effective: Pills or Patches?
Both HRT pills and patches can be highly effective for managing menopause symptoms. However, the effectiveness of each method may vary depending on your personal health, lifestyle, and preferences.
- Consistency of Hormones: Patches tend to provide a more consistent hormone level, which may make them a better option for those who want steady relief without the fluctuations that can come with pills.
- Convenience: If you prefer something that requires less daily attention, patches might be a better choice because they only need to be changed a few times a week. However, some people find pills easier because they don’t have to worry about sticking the patch on correctly or ensuring it stays in place.
- Side Effects: Some women experience fewer side effects with patches because they avoid the digestive system. However, women who are prone to skin irritation might prefer pills instead.
Choose the Best HRT for Your Needs Today
When it comes to choosing between HRT patches and pills, both have their own advantages and disadvantages. Pills are traditional and easy to use but may come with digestive side effects. Patches offer consistent hormone release and are often more convenient for women who prefer not to take daily pills.
Looking for the best solution to manage your symptoms? Whether you prefer HRT patches or pills, we offer a variety of options to suit your needs. Explore different treatments, compare their benefits and side effects, and make an informed choice for your health. Shop online today and take the first step toward relief.

Authored By
HARMINDER ‘HARMY’ KAUR
BSc(hons) Pharmacy
GPhC Number: 2061107

Reviewed By
GURDEV SEHMI
BSc Pharm, MRPharmS, Independent Prescriber, Superintendent Pharmacist, Clinical Lead
GPhC Number: 2050925