Eliquis Apixaban

Eliquis (Apixaban) is used to lower the risk of stroke caused by a blood clot in people with a heart ...

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Eliquis contains the active substance apixaban and belongs to a group of medicines called anticoagulants. This medicine helps prevent the formation of blood clots by blocking Factor Xa, an important element of blood clotting.

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What is Eliquis?

Eliquis contains the active substance apixaban and belongs to a group of medicines called anticoagulants. This medicine helps prevent the formation of blood clots by blocking Factor Xa, an important element of blood clotting.

How does it work?

Apixaban is a powerful, direct, highly selective reversible oral inhibitor of factor Xa. It does not require antithrombin III for antithrombotic activity. Apixaban inhibits clot-bound and free factor Xa and prothrombinase activity. Apixaban has no direct effect on platelet aggregation but indirectly inhibits thrombin-induced platelet aggregation. By inhibiting factor Xa, apixaban prevents both thrombin formation and thrombus formation. Preclinical trials of apixaban in animal models demonstrated antithrombotic efficacy in preventing arterial and venous thrombosis at doses that preserved hemostasis.

What are the benefits of taking it?

Eliquis (Apixaban)  is used in adults:

  • to prevent the formation of a blood clot in the heart in patients with an irregular heartbeat (atrial fibrillation) and at least one additional risk factor. The blood clots can be detached, move to the brain and cause a stroke, or move to other organs avoiding proper irrigation of the same (also known as a systemic embolism). A stroke can be life-threatening and requires immediate medical attention.
  • to treat blood clots in the leg veins (deep vein thrombosis) and in the blood vessels of the lungs (pulmonary embolism), and to prevent these blood clots reappear in the blood vessels of the legs and/or lungs.

How do I use it and its dosage?

Always use this medicine exactly as your doctor or pharmacist has told you. If in doubt, ask your doctor, pharmacist, or nurse.

Take the tablet with water. Eliquis can be taken with or without food.

Try to take the tablets at the same time each day to get a better treatment effect.

If you have trouble swallowing the whole tablet, talk to your doctor about other possible ways to take Eliquis. The tablet can be crushed and mixed with water, 5% glucose in water, apple juice or applesauce, immediately before taking it.

Shredding Instructions:

  • Crush the tablets with a mortar.
  • Transfer all the powder carefully into a suitable container, mixing the powder with a small amount, for example, 30 ml (2 tablespoons), of water or any of the mentioned liquids to make the mixture.
  • Ingest the mixture.
  • Rinse the mortar and pestle of the mortar that has been used to crush the tablet and the container, with a small amount of water or one of the other liquids (for example, 30 ml), and ingest that liquid.

If necessary, your doctor may also give you the crushed Eliquis tablet mixed in 60 ml of water or 5% glucose in water through a nasogastric tube.

Take Eliquis according to the following recommendations:

To prevent the formation of a blood clot in the heart of patients with an irregular heartbeat and at least one additional risk factor. The recommended dose of Eliquis is one Eliquis 5 mg tablet twice a day.

The recommended dose is one Eliquis 2.5 mg tablet twice a day if:

  • You have severely decreased kidney function
  • Two or more of the following factors apply to you: your blood test results suggest poor kidney function (serum creatinine value is 1.5 mg/dl (133 micromoles / l) or higher) you are 80 years of age or older Your weight is equal to or less than 60 kg

The recommended dose is one Eliquis tablet twice a day, for example, take one tablet in the morning and one in the evening. Your doctor will tell you how long the treatment should continue.

Side effects & precautions

Like all medicines, this medicine for heart Problems can cause side effects, although not everybody gets them. The most common side effect of Eliquis is bleeding, which can be life-threatening and requires immediate medical attention.

The following side effects have been reported when Eliquis is taken to prevent the formation of blood clots in the heart in patients with an irregular heartbeat and at least one additional risk factor.

Common side effects (may affect up to 1 in 10 people)

- Bleeding that includes:

  • In the eyes
  • in the stomach or intestine
  • rectum
  • blood in the urine
  • of the nose
  • gums
  • bruising and swelling
  • Anemia, which can cause tiredness or paleness
  • Low blood pressure that may cause fainting or a faster heartbeat
  • Nausea (general discomfort)
  • Blood tests can show:
  • an increase in gamma-glutamyl transferase (GGT)

Uncommon side effects (may affect up to 1 in 100 people)

- Bleeding:

  • in the brain or spinal column
  • in the mouth or coughing up blood
  • in the abdomen, or vagina
  • bright/red blood in the stool
  • bleeding after your operation including bruising and swelling, discharge of blood or fluid from the wound / surgical incision (suppuration), or injection site
  • hemorrhoidal
  • tests showing blood in the stool or urine
  • Decreased number of platelets in the blood (which can affect clotting)
  • Blood tests can show:
  • abnormal liver function
  • increased liver enzymes
  • increased bilirubin, a product derived from red blood cells, that can cause yellowing of the skin and eyes.
  • Acne
  • Itchiness
  • Hair loss
  • allergic reactions (hypersensitivity) that can produce swelling of the face, lips, mouth, tongue, and/or throat and difficulty breathing. Tell your doctor immediately if you experience any of these symptoms.

Rare side effects (may affect up to 1 in 1,000 people)

- Bleeding:

  • in the lungs or throat
  • within the space behind the abdominal cavity
  • in a muscle

The following side effects have been reported when Eliquis is taken to treat or prevent blood clots from reoccurring in the veins of the legs and in the blood vessels of the lungs.

Common side effects (may affect up to 1 in 10 people)

- Bleeding that includes:

  • of the nose
  • gums
  • blood in the urine
  • bruising and swelling
  • stomach, intestine or rectum
  • in the mouth
  • vaginal
  • Anemia, which can cause tiredness or paleness
  • Decreased number of platelets in the blood (which can affect clotting)
  • Nausea (feeling sick)
  • Acne
  • Blood tests can show:- an increase in gamma-glutamyl transferase (GGT) or alanine aminotransferase (GPT)

Uncommon side effects (may affect up to 1 in 100 people)

  • - Low blood pressure that may cause fainting or a faster heartbeat

- Bleeding:

  • In the eyes
  • in the mouth or coughing up blood
  • bright/red blood in the stool
  • tests showing blood in the stool or urine
  • bleeding after an operation including bruising and swelling, discharge of blood or fluid from the wound / surgical incision (suppuration), or injection site
  • hemorrhoidal
  • in a muscle
  • Itchiness
  • Hair loss
  • allergic reactions (hypersensitivity) that can produce swelling of the face, lips, mouth, tongue and/or throat and difficulty breathing. Tell your doctor immediately if you experience any of these symptoms.
  • Blood tests can show:
  • abnormal liver function
  • increased liver enzymes
  • increased bilirubin, a product derived from red blood cells, that can cause yellowing of the skin and eyes.

Rare side effects (may affect up to 1 in 1,000 people)

Bleeding:

  • in the brain or spinal column
  • in lungs

Buying Eliquis online.

You can buy Eliquis online through one of the UK’s leading online pharmacies, Pharmacy Planet. It's easy and convenient. You will need to fill out a short assessment and the item will be delivered directly to your door. If you want to buy this heart medication online, use Pharmacy Planet, a UK pharmacy you can trust.

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