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UK licenced medication
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Premique is a hormonal drug. The drug is used as part of hormonal therapies in women. The active ingredients in Premique are estradiol (an estrogen hormone) and medroxyprogesterone (a progestin hormone). The former complement the lack of estrogens, helping to reduce the symptoms of menopause.
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What is Premique?
How does it work?
As menopause occurs, women begin to produce less estrogen, resulting in a decrease in estrogen levels in the blood. As a result, the decrease in estrogen levels produces several uncomfortable symptoms. Premique is a period less therapy, which means that you will not experience monthly bleeding with this treatment.
The benefits of Premique are thanks to the components it contains, two active ingredients, conjugated estrogens, which complement the lack of estrogens, helping to reduce the symptoms of menopause. The second principle is medroxyprogesterone acetate. For women who have not had a hysterectomy, increased estrogen levels can stimulate the growth of the uterine lining, which can cause uterine cancer. The inclusion of progesterone is done to counteract the effects of estrogen on the uterine lining, which reduces the risk of cancer.
What are the benefits of taking it?
Premique tablets for Hormone Replacement Therapy (HRT for women), it is a continuous combination of treatments, and are used to alleviate menopausal symptoms. They contain synthetic versions of estrogens and progesterone, which help restore naturally lowered hormone levels. Premique is prescribed, among other things, for the treatment of the following menopausal symptoms:
- Hot flushes
- An increased level of sweat (night)
- Bone loss
- Sleep disorders
- Dry mucous membranes (in eyes and vagina)
- Humor changes.
The progestin hormone contained in Premique (Climopax) protects the uterus from side effects. Therefore, this drug is mainly prescribed to women whose uterus has not been removed.
How do I use it?
Its dosage
Premique is generally prescribed in the lowest dose for the shortest period of time, in a 28-day package. For both Premique dosages, it is recommended to take one tablet at the same time every day, with no breaks between packages. If you are not currently taking another HRT or HRT with no period, you can start the first Premique pack at any time. If you are using a treatment that allows you to have periods, it is generally recommended that you start this HRT after the cycle of your previous therapy ends.
It is important that you take this medicine as prescribed by your doctor. If you forget to take a pill, you should take it as soon as possible. However, if more than 12 hours pass, it is recommended to skip the dose and continue treatment at the usual time. Do not double the dose to make up for the forgotten pill.
Side effects & precautions
It is essential to be aware of the side effects that this product can induce, since some may require that you go to the doctor urgently. Visit your nearest doctor or hospital right away if you notice any signs that may be an indication of the following: a heart attack or stroke; an allergic reaction; liver disease; migraine for the first time or one that is worse than normal; breast cancer or any type of cancer that is sensitive to estrogens; a blood clot; or increased blood pressure.
Very common (1 in 10 women or more):
Chest pain.
Common (1 in 10 women or less):
The appearance of bleeding or spotting, inflammation of the vagina, menstrual pain, tender or swollen breasts, nipple discharge, depression, muscle and joint pain, leg cramps, weight fluctuations, or altered triglyceride levels.
Uncommon (1 in 100 women or less):
Oral thrush, irregular menstrual bleeding, vaginal discharge, feeling unwell, bloating, abdominal pain, headache, blood clot in a vein, migraine, dizziness, mood changes, libido changes, swelling of the face or ankles, itching, acne, intolerance to contact lenses, gallbladder disease, or hair loss.
Rare (1 in 1,000 women or less):
Irritability, vomiting, changes in breast tissue, increased hair growth, worsening of asthma symptoms, increase in fibroid size, ovarian cancer, worsening of epilepsy, myocardial infarction, stroke, or inflammation of the pancreas.
Precautions and Warnings
This treatment is not suitable for those who have a history of the following diseases: heart conditions such as angina; heart attack or stroke; blood clots, or any disorder that affects blood clotting; breast cancer, or any type of cancer that responds to estrogens; porphyria; lactose or sucrose intolerance; recent excessive vaginal bleeding; endometrial hyperplasia; or severe liver disease.
People with the following conditions are also recommended to take special care or have regular check-ups when using this medicine: endometriosis; uterine fibers; increased susceptibility to blood clots; any high-risk factors related to breast cancer or another form of estrogen-dependent cancer; high blood pressure; liver or kidney dysfunction; diabetes; gallbladder disease; migraine; systemic lupus erythematosus; epilepsy; hypocalcemia; hypertriglyceridaemia; asthma; or otosclerosis.
Buying Premique online.
