Facebook Pixel
New Patients – Get 10% Off Your First Consultation with Code: NEW10 at Checkout
Consult
Select
Checkout
01
Select

the items you wish
to order

02
Order reviewed

by our qualified
prescriber

03
Delivered

to your door step

Your Selection

Please use the options provided to make your final selection.

prodName
Linaclotide
£87
Total
Consult
Select
Checkout
Please make a selection

Please note that whilst you are able to request the medicine strength and size required,
we will only be able to send on approval from our in house pharmacist.

Starts at £87.00
Manesha
You’re almost there!

It is the prescribers duty to ensure that the medicine is being used safely and appropriately. please answer a few questions about yourself to help us process your request.

- Manesha

Customer Service Team

Confidentiality & Authenticity Assured

  • Fully Regulated UK Pharmacy
  • Authentic UK sourced medicines only.
  • Trading for more than 10 years.
  • Information Governance lead ensures all data is confidential

Need Help With Your Questionnaire?

Our customer service team is on hand Monday-Friday to help you with your queries.

Please call us on 08009788956 or
email us at: headoffice@pharmacyplanet.com

Price Comparison

Select your preferred options and see the best price

PackPrice (£)
Constella290mcg28 Capsules87.00
Constella290mcg56 Capsules157.00
Constella290mcg84 Capsules233.00

It looks like you missed filling in questions from the last consultation.Click Here to submit your response.

  • No hidden fees

  • Secure checkout

  • UK Regulated online pharmacy

  • Trusted by over 100,000+ customers

Constella Capsules | Linaclotide Guanylate Cyclase Agonist for IBS-C & Chronic Constipation

If constipation linked to IBS is affecting your daily comfort, it can feel frustrating and unpredictable. Bloating, discomfort, and difficulty passing stools can build up over time. Constella capsules are designed to address this directly by improving bowel movement and easing discomfort.

Containing linaclotide, this prescription IBS therapy works differently from standard laxatives. It targets the gut lining to increase fluid and movement, offering effective IBS constipation relief and supporting long-term digestive health.

What Are Constella / Linaclotide Capsules Used For?

Constella capsules are used to treat moderate to severe IBS with constipation (IBS-C). They are commonly prescribed for:

  • IBS-related constipation.
  • Chronic constipation treatment.
  • Abdominal discomfort and bloating.
  • Improving bowel movement frequency.

This makes Constella a targeted bowel movement aid for people whose symptoms are not controlled by standard treatments.

How Constella / Linaclotide Capsules Work in the Gut

Constella capsules work by increasing fluid in the bowel and stimulating movement. The active ingredient linaclotide attaches to specific receptors in the gut lining. This action:

  • Increases fluid secretion into the intestines.
  • Softens stools for easier passing.
  • Speeds up bowel movement.
  • Reduces pain signals from the gut.

This dual effect makes it highly effective for both intestinal relief and improving overall colon care.

How to Take Constella / Linaclotide Capsules

Constella capsules should be taken exactly as prescribed for the best results.

General guidance:

  • Swallow the capsule whole with water.
  • Do not crush or chew the capsule.
  • Take on an empty stomach.

Typical dosage: One 290 microgram capsule once daily.

When to take: Take at least 30 minutes before food. Take at the same time each day.

Important tips: Start treatment when you can stay at home, as bowel movements may increase. If you are using laxatives, they may need to be reduced or stopped. Continue taking it regularly, even if improvement takes time.

Consistent use supports effective chronic constipation treatment and improved intestinal relief.

Who Can Use Constella / Linaclotide Capsules?

Constella capsules are suitable for adults with IBS-related constipation. They may be appropriate for:

  • Adults with moderate to severe IBS-C.
  • Individuals needing long-term bowel movement aid.
  • Patients not responding to standard treatments.

This prescription IBS therapy is used under supervision to ensure safe and effective treatment.

Who Should Not Take Constella / Linaclotide Capsules?

Constella capsules may not be suitable for people with certain conditions. Avoid or take extra care if you:

  • Are pregnant or planning pregnancy.
  • Are breastfeeding.
  • Have a suspected bowel blockage.
  • Have had an allergic reaction to similar medicines.

A full consultation ensures safe and appropriate digestive medication use.

Possible Side Effects of Constella / Linaclotide Capsules

Like all medicines, Constella capsules can cause side effects, although many people tolerate them well.

Common side effects:

  • Diarrhoea.
  • Abdominal discomfort.
  • Bloating or wind.

Serious side effects:

  • Severe or persistent diarrhoea.
  • Dehydration symptoms.
  • Dizziness or weakness.

Seek urgent medical attention if any severe symptoms occur.

Possible Interactions with Constella / Linaclotide Capsules

Constella capsules may affect how other medicines work, especially if diarrhoea occurs. Important considerations:

  • Oral contraceptives may be less effective if diarrhoea occurs.
  • Other laxatives may need to be adjusted.

This ensures safe and effective gut treatment.

Important Advice Before Taking Constella / Linaclotide Capsules

Regular use and monitoring of symptoms are important during treatment. Key advice:

  • Stay well hydrated, especially if diarrhoea occurs.
  • Be aware that symptom relief for bloating may take several weeks.
  • Take consistently for best results.

Why Do People Prefer Constella / Linaclotide Capsules?

Constella capsules are chosen for their targeted approach to IBS-related constipation. People often prefer this treatment because:

  • It works differently from traditional laxatives.
  • It improves both bowel movement and discomfort.
  • It is suitable for long-term gut treatment.
  • It fits into structured digestive medication plans.

For many, it offers a more complete solution for managing IBS with constipation.

Constipation & Bowel Movement Treatments

These treatments help soften stools or improve bowel movement frequency in people with constipation-related symptoms. The table below compares commonly prescribed constipation and bowel movement treatments and how they are typically used.

ProductWhat it isWhat it's mainly used forHow you usually use itWhat to expect
Movicol SachetsOsmotic laxative sachetsConstipation and hard stoolsTaken as prescribedHelps draw water into the bowel to soften stools.
Constella (Linaclotide) CapsulesIBS constipation treatmentIBS with constipation (IBS-C)Taken once dailyHelps improve bowel movements and reduce bloating or discomfort.

Important: This comparison is for general information only and does not replace medical advice. A prescriber will decide which treatment is suitable for you following an online consultation.

How to Order Constella / Linaclotide Capsules Online from Pharmacy Planet

Ordering Constella capsules is simple and secure.

  1. Complete an Online Consultation — Provide details about your symptoms and health.
  2. Prescription Review — A UK-registered prescriber confirms if Constella capsules are suitable.
  3. Discreet Delivery — If approved, your treatment is delivered directly to your chosen address.
Constella (Linaclotide) Capsules

If constipation linked to IBS is affecting your daily comfort, it can feel frustrating and unpredictable. Bloating, discomfort, and difficulty passing stools can build up over time. Constella capsules are designed to address this directly by improving bowel movement and easing discomfort.

Containing linaclotide, this prescription IBS therapy works differently from standard laxatives. It targets the gut lining to increase fluid and movement, offering effective IBS constipation relief and supporting long-term digestive health.

Constella capsules are used to treat moderate to severe IBS with constipation (IBS-C). They are commonly prescribed for:

  • IBS-related constipation.
  • Chronic constipation treatment.
  • Abdominal discomfort and bloating.
  • Improving bowel movement frequency.

This makes Constella a targeted bowel movement aid for people whose symptoms are not controlled by standard treatments.

Constella capsules work by increasing fluid in the bowel and stimulating movement. The active ingredient linaclotide attaches to specific receptors in the gut lining. This action:

  • Increases fluid secretion into the intestines.
  • Softens stools for easier passing.
  • Speeds up bowel movement.
  • Reduces pain signals from the gut.

This dual effect makes it highly effective for both intestinal relief and improving overall colon care.

Constella capsules should be taken exactly as prescribed for the best results.

General guidance:

  • Swallow the capsule whole with water.
  • Do not crush or chew the capsule.
  • Take on an empty stomach.

Typical dosage: One 290 microgram capsule once daily.

When to take: Take at least 30 minutes before food. Take at the same time each day.

Important tips: Start treatment when you can stay at home, as bowel movements may increase. If you are using laxatives, they may need to be reduced or stopped. Continue taking it regularly, even if improvement takes time.

Consistent use supports effective chronic constipation treatment and improved intestinal relief.

Constella capsules are suitable for adults with IBS-related constipation. They may be appropriate for:

  • Adults with moderate to severe IBS-C.
  • Individuals needing long-term bowel movement aid.
  • Patients not responding to standard treatments.

This prescription IBS therapy is used under supervision to ensure safe and effective treatment.

Constella capsules may not be suitable for people with certain conditions. Avoid or take extra care if you:

  • Are pregnant or planning pregnancy.
  • Are breastfeeding.
  • Have a suspected bowel blockage.
  • Have had an allergic reaction to similar medicines.

A full consultation ensures safe and appropriate digestive medication use.

Like all medicines, Constella capsules can cause side effects, although many people tolerate them well.

Common side effects:

  • Diarrhoea.
  • Abdominal discomfort.
  • Bloating or wind.

Serious side effects:

  • Severe or persistent diarrhoea.
  • Dehydration symptoms.
  • Dizziness or weakness.

Seek urgent medical attention if any severe symptoms occur.

Constella capsules may affect how other medicines work, especially if diarrhoea occurs. Important considerations:

  • Oral contraceptives may be less effective if diarrhoea occurs.
  • Other laxatives may need to be adjusted.

This ensures safe and effective gut treatment.

Regular use and monitoring of symptoms are important during treatment. Key advice:

  • Stay well hydrated, especially if diarrhoea occurs.
  • Be aware that symptom relief for bloating may take several weeks.
  • Take consistently for best results.

Constella capsules are chosen for their targeted approach to IBS-related constipation. People often prefer this treatment because:

  • It works differently from traditional laxatives.
  • It improves both bowel movement and discomfort.
  • It is suitable for long-term gut treatment.
  • It fits into structured digestive medication plans.

For many, it offers a more complete solution for managing IBS with constipation.

Constipation & Bowel Movement Treatments

These treatments help soften stools or improve bowel movement frequency in people with constipation-related symptoms. The table below compares commonly prescribed constipation and bowel movement treatments and how they are typically used.

ProductWhat it isWhat it's mainly used forHow you usually use itWhat to expect
Movicol SachetsOsmotic laxative sachetsConstipation and hard stoolsTaken as prescribedHelps draw water into the bowel to soften stools.
Constella (Linaclotide) CapsulesIBS constipation treatmentIBS with constipation (IBS-C)Taken once dailyHelps improve bowel movements and reduce bloating or discomfort.

Important: This comparison is for general information only and does not replace medical advice. A prescriber will decide which treatment is suitable for you following an online consultation.

Ordering Constella capsules is simple and secure.

  1. Complete an Online Consultation — Provide details about your symptoms and health.
  2. Prescription Review — A UK-registered prescriber confirms if Constella capsules are suitable.
  3. Discreet Delivery — If approved, your treatment is delivered directly to your chosen address.
Frequently Asked Questions

Many people notice bowel movements improve within a few days, but full relief from bloating and discomfort can take several weeks with regular use.

Yes, diarrhoea is common at the start. It usually settles as your body adjusts, especially when taken before food as advised.

Taking it at least 30 minutes before food reduces the risk of diarrhoea and allows the medicine to work properly in the gut.

Yes, it reduces pressure in the gut and improves bowel movement, which can ease bloating and abdominal discomfort over time.

It works differently from standard laxatives. It increases fluid in the gut and reduces pain signals, offering more targeted IBS relief.

Stop taking it temporarily, stay hydrated, and restart once symptoms settle. Ongoing severe diarrhoea should be reviewed.

It can be taken at any time, but it must be on an empty stomach and taken consistently at the same time each day.

If diarrhoea occurs, it can reduce how well the pill works, so extra precautions may be needed during treatment.

Yes, it is often used long-term to manage symptoms and maintain regular bowel movement in IBS with constipation.

Skip the missed dose and take your next dose as normal the following day. Do not take two capsules together.

How it works
Start Consultation
Complete our online
clinical consultation

Answer a few questions on your health and your fitness goals.

Setup Coaching
Clinical
assessment

Our clinicians will review your clinical questionnaire to make sure treatment is right for you.

Ongoing Support
Welcome
aboard!

Once approved, you will access our wealth of experience and resources curated by our team and begin your clinical journey.

What our patients are saying

Need Help?

question mark
Do you have a question about weight loss treatment?

Start your weight loss journey heading in the right direction. Our team are here to help. Whether you’re unsure about which medicine is right for you or need help navigating the world of weight loss drugs, our team are on hand to help you make the right decision. We can put you in touch with one of our experienced weight loss clinicians so you can be sure you’re making the best decision with the most accurate information.

To get in touch, contact our Customer Service team on 0800 978 8956 or email headoffice@pharmacyplanet.com.

Meet the team
Pharmacist Image

Review By

HARMINDER ‘HARMY’ KAUR

Last Updated On : Mar 13 2026

BSc(hons) Pharmacy

GPhC Number: 2061107

Pharmacist Image

Authored By

GURDEV SEHMI

Last Reviewed On : Mar 23 2026

BSc Pharm, MRPharmS, Independent Prescriber, Superintendent Pharmacist, Clinical Lead

GPhC Number: 2050925