Livial Tablets

Livial is a medicine used as hormone replacement therapy (HRT). Livial tablets contain the active substance tibolone, a synthetic hormone ...
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About Livial Tablets

Livial tablets provide relief from menopausal symptoms, including osteoporosis. It is a form of hormone replacement therapy (HRT). Livial contains one ingredient, Tibolone, which breaks down in the body into components which emulate the sex hormones oestrogen, progesterone and testosterone. In this way, it is different from most HRT treatments, which directly contain these sex hormones. Another difference is that Livial also increases testosterone levels, which has the effect of limiting some of the negative side effects of HRT. Livial is most similar to continuous combined forms of HRT. This form of HRT does not involve a regular period. For this reason, Livial is suited for women who have gone at least a year without a menstrual bleed.

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What is Livial?

Livial belongs to the group of drugs for Hormone Replacement Therapy. Contains tibolone, a synthetic sex hormone. Livial is indicated in postmenopausal women in which at least 12 months have elapsed since their last natural period. Livial is used for the relief of post-menopausal symptoms During menopause, the amount of estrogen produced by the woman's body decreases. This can cause symptoms like sweating and hot flashes. Livial relieves these symptoms after menopause. Livial will only be prescribed if the patient's symptoms seriously hinder his daily life.

How does it work?

Following oral administration, the main active Livial tablet ingredient, tibolone, is rapidly metabolized into three components, which all three contribute to the pharmacodynamic profile of Livial. Two of the metabolites (3α-OH-tibolone and 3β-OHtibolone) have estrogenic activity, while the third metabolite (Δ4 isomer of tibolone) has progestogenic and androgenic activities. Livial replaces the loss of estrogen production in postmenopausal women and relieves menopause symptoms.

What are the benefits of taking it?

Livial is used to treat symptoms of menopause, including:

  • Hot flushes
  • Night sweats
  • Sleep disorders
  • Dryness of the mucous membranes (eyes, vagina)
  • Mood swings, nervousness, depression, irritability.

In some cases, Livial is also prescribed to prevent osteoporosis years after menopause. Livial is especially ideal for women experiencing natural menopause who have not had a period in more than 12 months and who have not had their ovaries removed. If you are going through menopause, but are still having your period, you may need to take a different hormone replacement medicine.

How do I use it and its dosage?

Always use this medicine exactly as your doctor has told you. If in doubt, consult your doctor or pharmacist again. For more information, please see the patient information leaflet.

How much Livial you should take and for how long

Your doctor will prescribe the lowest possible dose to treat your symptoms for the shortest possible time. Consult your doctor if you think the dose is too high or too low.

Unless your doctor has prescribed a different dose, the usual dose is one tablet a day after a meal, preferably at the same time each day. Do not take a progestogen preparation in addition to Livial. 

How to take Livial

Take the tablets with a little water or another drink, preferably at the same time each day.

What to consider when starting treatment with Livial

If you went through menopause naturally, you should start taking Livial one year after your last menstrual bleeding. If your ovaries have been removed by surgery, you can start taking Livial immediately.

If you plan to take Livial and have had irregular or unexpected vaginal bleeding, please consult your doctor before starting treatment with Tibolona Aristo so that the possibility of any malignancy can be excluded.

If you wish to switch from medication to Tibolona Aristo and were previously taking estrogen and progestin medication, please ask your doctor what consideration should be taken into account.

How long should you take Livial

Your doctor will aim to make treatment as short as possible. Usually, an improvement in symptoms is achieved within a few weeks.

Side effects & precautions

Like all medicines, Livial can cause side effects, although not everybody gets them.

The following diseases occur more often in women who follow HRT (Hormone Replacement Therapy) compared to those who do not:

  • Breast cancer
  • Abnormal growth or cancer of the lining of the uterus (endometrial hyperplasia or cancer)
  • Ovarian cancer
  • Blood clots in the veins of the legs or lungs (venous thromboembolism)
  • Heart disease
  • Stroke
  • Probable memory loss if HRT started at an age above 65 years.

Talk to your doctor or pharmacist if you are concerned about any of the side effects that you think may be caused by Livial.

The following section details the known Livial side effects and their frequency:

Common (may affect up to 1 in 10 women):

  • vaginal bleeding or spotting
  • stomach ache
  • weight gain
  • breast pain
  • unusual hair growth
  • vaginal problems such as increased discharge, itching, and irritation
  • thickening of the lining of the uterus
  • vaginal yeast infection (eg, yeast infection)
  • pelvic pain
  • changes in the tissue of the cervix
  • inflammation of the lips and vagina (called vulvovaginitis)
  • smear abnormalities of the cervix

Uncommon (may affect up to 1 in 100 women):

  • acne
  • nipple or breast pain
  • fungal infections
  • dizziness, headache, migraine
  • depression
  • skin problems such as rashes
  • vision loss or blurred vision
  • stomach or intestinal discomfort
  • fluid retention
  • joint or muscle pain
  • changes in laboratory tests of liver function

In combination with other Hormone Replacement Therapies, the following side effects have been reported:

  • gallbladder disease
  • skin disorders:
  • discoloration of the skin, especially of the face and neck, known as "pregnancy spots" (chloasma)
  • painful reddish nodules on the skin (erythema nodosum)
  • rash with redness or ulcers (erythema multiforme)
  • bleeding from the skin (vascular purpura)

Buying Livial online.

You can buy Livial tablets online through one of the UK’s leading online pharmacies, Pharmacy Planet. It's easy and convenient. You will need to fill out a short assessment and the item will be delivered directly to your door. If you want to buy this HRT Treatment medication online, use Pharmacy Planet, a UK pharmacy you can trust.
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