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Creon is a prescription medicine used to treat conditions where the pancreas does not produce enough digestive enzymes, such as cystic fibrosis, chronic pancreatitis, and pancreatic cancer. It contains natural enzymes from pigs that help the body break down fats, proteins, and carbohydrates. Creon is usually taken with meals or snacks, and the capsules should be swallowed whole with water or sprinkled onto a small amount of soft acidic food if swallowing is difficult. Common side effects include stomach pain, bloating, diarrhoea, and constipation. It is not suitable for people with a pork allergy, and high doses may increase the risk of a rare bowel condition.
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-10 000 iu100 capsules35.00
-10 000 iu200 capsules70.00
-10 000 iu300 capsules105.00

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Creon Capsules | Pancreatic Enzyme Supplement for Exocrine Pancreatic Insufficiency

Eating should be something you enjoy, not something that leaves you feeling uncomfortable, bloated, or worried about symptoms afterwards. But when your pancreas is not working properly, even simple meals can become difficult to digest.

Creon capsules are designed to restore that balance. As a trusted pancreatic enzyme therapy, Creon replaces the enzymes your body is missing, allowing you to digest food properly and absorb nutrients more effectively.

What Are Creon Capsules, and What Are They Used For?

Creon capsules are a prescription enzyme supplement used to treat conditions where the pancreas does not produce enough digestive enzymes. This is known as pancreatic insufficiency, and it can happen due to chronic pancreatitis, pancreatic surgery or damage, or cystic fibrosis or other digestive disorders.

Without these enzymes, your body struggles to break down food, especially fats. This can lead to symptoms like greasy stools, abdominal discomfort, and poor nutrient absorption. Creon provides the enzymes your body needs to support normal digestion.

How Creon (Pancreatic Enzyme) Works in the Body

Creon works by replacing the enzymes your pancreas would normally produce. Each capsule contains key digestive enzymes: Lipase, which breaks down fats; Protease, which breaks down proteins; and Amylase, which breaks down carbohydrates.

When taken with food, these enzymes mix with your meal in the stomach and support proper digestion. This improves nutrient absorption and reduces uncomfortable symptoms linked to poor digestion.

How to Take Creon Capsules

Creon must be taken correctly to work effectively. General guidance includes taking Creon with every meal or snack, taking it at the start of eating so it mixes with food, swallowing capsules whole with water, and not crushing or chewing the capsules.

Dosage can vary depending on your needs. Typical advice may include 1 to 3 capsules with meals, adjusting the dose depending on fat content in food. Your prescriber will guide you during your consultation, but your symptoms may also help determine the right dose over time.

Who Can Use Creon Capsules?

Creon is suitable for adults and children diagnosed with pancreatic enzyme deficiency. It may be prescribed if you have pancreatic insufficiency, have had pancreatic surgery, are undergoing pancreatitis treatment, or experience ongoing digestive symptoms linked to enzyme deficiency.

However, it may not be suitable if you are allergic to pork-derived products, or have certain bowel conditions that require monitoring. A clinical assessment ensures the correct diagnosis and dosing.

What Happens If You Do Not Take Creon? Skipping Creon can lead to ongoing digestive problems. Without enzyme replacement, food is not properly broken down, fat digestion becomes difficult, stools may become loose, oily, and difficult to flush, you may lose weight or struggle to gain weight, and important vitamins may not be absorbed properly. Taking Creon consistently ensures your body gets the nutrition it needs.

Possible Side Effects of Creon Capsules

Creon is generally well tolerated, but side effects can occur.

Common Side Effects:

  • Stomach pain
  • Bloating or gas
  • Changes in bowel movements
  • Nausea or vomiting

These are usually mild and manageable.

Serious Side Effects:

  • Allergic reactions such as rash, itching, or swelling
  • Breathing difficulty
  • Severe abdominal pain or bowel changes
  • Increased uric acid levels, which may affect joints

If any serious symptoms occur, medical attention is required.

Possible Interactions with Creon Capsules: Creon has very few known drug interactions, but it is still important to stay informed. During your consultation, mention if you are taking other prescription medicines, supplements or vitamins, or treatments for digestive or metabolic conditions. This ensures safe use alongside other therapies.

Why Do People Choose Creon Capsules?

Creon is widely used by people who need reliable, long-term digestive support. People often choose Creon because it directly replaces missing pancreatic enzymes, improves digestion of fats, proteins, and carbohydrates, supports better nutrient absorption and weight stability, reduces symptoms like bloating, greasy stools, and discomfort, and is a well-established prescription enzyme therapy. For many, Creon becomes an essential part of daily digestive health.

How Does the Ordering Process Work at Pharmacy Planet?

Getting Creon through Pharmacy Planet is simple and clinically guided.

  1. Complete an online consultation and provide details about your symptoms and medical history.
  2. A UK-registered prescriber assesses your suitability.
  3. If approved, your medication is dispensed and delivered discreetly.
Creon Capsules

Creon capsules are a prescription pancreatic enzyme therapy that replaces the digestive enzymes your pancreas is missing, restoring proper digestion and nutrient absorption when the pancreas is not working properly.

A prescription enzyme supplement for pancreatic insufficiency caused by chronic pancreatitis, pancreatic surgery or damage, or cystic fibrosis. Replaces missing enzymes to support normal digestion of fats, proteins, and carbohydrates.

Each capsule contains lipase (breaks down fats), protease (breaks down proteins), and amylase (breaks down carbohydrates). Taken with food, these enzymes mix with meals in the stomach to support proper digestion and improve nutrient absorption.

Take with every meal or snack, at the start of eating so it mixes with food. Swallow whole with water — do not crush or chew. Typical dose: 1–3 capsules per meal. Dose may vary with fat content. Your prescriber will guide the correct amount.

Suitable for adults and children with pancreatic enzyme deficiency, pancreatic insufficiency, post-pancreatic surgery, pancreatitis treatment, or ongoing digestive symptoms from enzyme deficiency.

Not suitable for allergy to pork-derived products or certain bowel conditions. Clinical assessment ensures correct diagnosis and dosing. Skipping Creon leads to poor fat digestion, oily stools, weight loss, and vitamin malabsorption.

Common: Stomach pain, bloating/gas, changes in bowel movements, nausea/vomiting — usually mild

Serious: Allergic reactions (rash/itching/swelling), breathing difficulty, severe abdominal pain/bowel changes, increased uric acid (joint effects)

Seek medical attention for serious symptoms. Very few drug interactions — mention all medicines, supplements, and vitamins during consultation.

Directly replaces missing pancreatic enzymes, improves digestion of fats/proteins/carbohydrates, supports nutrient absorption and weight stability, reduces bloating and greasy stools, and is a well-established prescription enzyme therapy for long-term digestive health.

Getting Creon through Pharmacy Planet is simple and clinically guided.

  1. Complete an online consultation and provide details about your symptoms and medical history.
  2. A UK-registered prescriber assesses your suitability.
  3. If approved, your medication is dispensed and delivered discreetly.
Frequently Asked Questions

Yes, Creon should be taken every time you eat, including snacks. It needs to mix with food in your stomach to properly support digestion.

If you miss a dose, your body may not digest the meal properly. This can lead to bloating, stomach discomfort, or oily stools after eating.

Yes, your dose may change depending on your meal. Higher-fat meals often require more capsules, but any changes should be discussed with your prescriber.

Creon starts working immediately as it mixes with food in your stomach. You may notice improvement in digestion and symptoms within a few meals.

Yes, many people take Creon long-term. If your pancreas is permanently damaged, you may need to continue enzyme therapy for life.

No, Creon is a prescription-strength pancreatic enzyme therapy. It contains specific enzymes in controlled doses that over-the-counter products do not provide.

Yes, the capsule can be opened and the contents mixed with soft acidic food if needed. The granules should not be crushed or chewed.

Creon improves digestion and allows your body to absorb nutrients properly. This can support healthy weight maintenance or gradual weight gain if needed.

You do not need to avoid specific foods, but very fatty meals may require a higher dose. A balanced diet works best alongside enzyme therapy.

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Review By

GURDEV SEHMI

Last Updated On : Mar 13 2026

BSc Pharm, MRPharmS, Independent Prescriber, Superintendent Pharmacist, Clinical Lead

GPhC Number: 2050925

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Authored By

GURDEV SEHMI

Last Reviewed On : Mar 23 2026

BSc Pharm, MRPharmS, Independent Prescriber, Superintendent Pharmacist, Clinical Lead

GPhC Number: 2050925