Competact is a medicine that reduces the level of glucose (sugar) in the blood. This medicine consists of 2 active ...

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What is Competact?

Competact contains pioglitazone and metformin. It is an antidiabetic medication that is used in adult patients to treat type 2 (non-insulin-dependent) diabetes mellitus when treatment with metformin alone is not sufficient. This type of type 2 diabetes generally occurs in adults, mainly as a consequence of being overweight and if the body either does not produce enough insulin (a hormone that controls blood sugar levels) or is not able to effectively use the insulin produced. Your doctor will monitor the effect that Competact is having on you between 3 and 6 months after treatment started. Competact is used to control blood sugar levels if you have type 2 diabetes, allowing your body to make better use of the insulin it produces.

How does it work?

Competact combines two antihyperglycemic active ingredients with complementary mechanisms of action to improve glycemic control in patients with type 2 diabetes mellitus: pioglitazone, belonging to the thiazolidinedione class and metformin hydrochloride, belonging to the biguanide class. Thiazolidinediones work mainly by reducing insulin resistance and biguanides work by decreasing endogenous hepatic glucose production.

What are the benefits of taking it?

Competact Pioglitazone uses include being indicated as a second-line treatment for adult patients with type 2 diabetes mellitus, especially overweight patients, who do not achieve sufficient glycemic control with the maximum tolerated dose of oral metformin monotherapy.

How do I use it and its dosage?

After initiation of pioglitazone treatment, patients should be monitored 3 to 6 months later to assess response to treatment (eg reduction in HbA1c). In patients who do not show an adequate response, pioglitazone should be discontinued. Considering the potential risks of prolonged treatment, clinicians should confirm in subsequent routine check-ups that the benefit of pioglitazone is maintained.

Always use this medicine exactly as your doctor or pharmacist has told you. If in doubt, consult your doctor or pharmacist again.

The recommended Competact Pioglitazone dosage is one tablet twice a day. If necessary, your doctor may prescribe a different dose. If you have reduced kidney function, your doctor may prescribe a lower dose that may need to be given as separate pioglitazone and metformin tablets.

Take the tablets with a glass of water. You should take the tablets with or just after meals to reduce the risk of digestive discomfort.

If you are following a special diabetic diet, stick to it while taking Competact.

You will need to check your weight regularly. If you gain weight, tell your doctor.

Your doctor will regularly order blood tests during treatment with Competact to check the correct function of your liver. At least once a year (more often if you are old or have kidney problems), your doctor will check how well your kidneys are working.

If you take more Competact than you should

If you accidentally take too many tablets, or if a child or someone else takes your medicine, tell your doctor or pharmacist immediately. Your blood sugar level may drop below normal, but it can be increased by taking sugar. It is recommended that you bring some lumps of sugar, candy, cookies, or some sugary fruit juice.

Side effects & precautions

Like all medicines, these diabetes tablets can cause side effects, although not everybody gets them.

Competact can cause a very rare side effect (may affect up to 1 user in 10,000), but a very serious one, called lactic acidosis. If this occurs, you should stop taking Competact and start Contact a doctor or the nearest hospital immediately, as lactic acidosis can lead to coma Rarely (may affect up to 1 in 100 people), bladder cancer has developed in patients taking Competact. Signs and symptoms include blood in the urine, painful urination, or an urgent need to urinate. If you experience any of these symptoms contact your doctor immediately.

Bone fractures: have been reported frequently (may affect up to 1 in 10 people) in both women and men taking Competact (frequency cannot be estimated from the available data). Check with your doctor as soon as possible if you experience this side effect.

Cases of blurred vision due to swelling (or fluid) in the fundus (macular edema) have been reported (frequency cannot be estimated from the available data). If you experience these symptoms for the first time, tell your doctor as soon as possible. If you have already had blurred vision and your symptoms worsen, see your doctor as soon as possible.

Allergic reactions with unknown frequency (cannot be estimated from the available data) have been reported in patients treated with Competact. If you have a severe allergic reaction, including hives and swelling of the face, lips, tongue or throat that can make it difficult for you to breathe or swallow, stop taking this medication and consult your doctor immediately.

Some patients have experienced the following side effects when taking Competact:

Very common (may affect more than 1 in 10 people)

  • stomach ache
  • sickness
  • vomiting
  • diarrhea
  • loss of appetite

Common (may affect up to 1 in 10 people)

  • localized swelling (edema)
  • weight gain
  • headache
  • Respiratory infection
  • vision disorders
  • joint pain
  • impotence
  • blood in the urine
  • reduced red blood cell count (anemia)
  • numbness
  • alteration of taste

Uncommon (may affect up to 1 in 100 people)

  • inflammation of the sinuses (sinusitis)
  • gases
  • difficulty sleeping (insomnia)

Very rare (may affect up to 1 user in 10,000)

  • decreased amount of vitamin B12 in the blood
  • redness of the skin
  • itchy skin
  • Urticaria

Buying Competact online.

You can buy Competact Pioglitazone tablets online through one of the UK’s leading online pharmacies, Pharmacy Planet. It's easy and convenient. You will need to fill out a short assessment and the item will be delivered directly to your door. If you want to buy Diabetes treatment medication online, use Pharmacy Planet, a UK pharmacy you can trust.

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