Eucreas
Eucreas is a medicine that regulates the level of glucose in the blood (level of sugar in the blood). The active ingredients in Eucreas are Vildagliptin: This active ingredient gives the pancreas more time to make insulin; The body can also better process glucose from meals. Metformin: This medication increases the body's sensitivity to insulin. By combining these active ingredients, Eucreas stabilizes and regulates the blood glucose level. Eucreas is prescribed for type 2 diabetes, formerly also called "old sugar." With this disease, the pancreas does not make enough insulin, which increases the level of glucose in the blood. This in turn leads to thirst, tiredness, frequent urination, and poor wound healing. Eucreas stabilizes the glucose level, reduces symptoms, and prevents complications.
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| Pack | Price (£) | ||
|---|---|---|---|
| - | 850mg/50mg | 60 Tablets | 55.00 |
| - | 850mg/50mg | 120 Tablets | 101.00 |
| - | 850mg/50mg | 180 tablets | 135.00 |
| - | 1000mg/50mg | 60 Tablets | 55.00 |
| - | 1000mg/50mg | 120 Tablets | 101.00 |
| - | 1000mg/50mg | 180 tablets | 135.00 |
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Eucreas is a combination of vildagliptin and metformin, which work together to help manage blood sugar levels in adult patients with type 2 diabetes. These two medicines combined within Eucreas can improve insulin sensitivity and regulate blood sugar levels in the body through the amount of glucose produced within the liver. This can help to stabilise your blood sugar throughout the day.
What is Eucreas?
Eucreas is used to treat adult patients with type 2 diabetes. This type of diabetes is also known as non-insulin-dependent diabetes mellitus. Type 2 diabetes occurs if the body does not make enough insulin or if the insulin produced does not work properly. It can also appear if the body produces too much glucagon. Insulin and glucagon are produced in the pancreas. Insulin helps reduce blood sugar levels, especially after meals. Glucagon promotes sugar production by the liver and causes blood sugar levels to rise.
How does it work?
Eucreas combines two antidiabetic drugs with complementary mechanisms of action to improve glycemic control in patients with type 2 diabetes: vildagliptin, a member of the group of pancreatic islet enhancers, and metformin hydrochloride, a member of the biguanide group.
Vildagliptin, a member of the pancreatic islet enhancers group, is a potent and selective inhibitor of dipeptidyl peptidase 4 (DPP-4). Metformin works mainly by decreasing endogenous hepatic glucose production.
What are the benefits of taking it?
Eucreas uses includes being indicated in the treatment of type 2 diabetes mellitus:
- Eucreas is indicated for the treatment of adult patients who are unable to achieve sufficient glycemic control with the maximum tolerated dose of metformin as oral monotherapy or who are already being treated with the combination of vildagliptin and metformin in individual tablets.
- Eucreas is indicated in combination with a sulfonylurea (i.e. triple combination therapy) as an adjunct to diet and exercise in inadequately controlled adult patients with metformin and a sulfonylurea.
- Eucreas is indicated in triple combination therapy with insulin as an adjunct to diet and exercise to improve glycemic control in adult patients in whom a stable dose of insulin and metformin alone does not provide adequate glycemic control.
How do I use it and its dosage?
The dose of Eucreas that each person should take varies depending on their state. Your doctor will tell you exactly how much Eucreas to take.
Always use this medicine exactly as your doctor has told you. If in doubt, consult your doctor or pharmacist again.
The recommended eucreas tablets dosage is one 50 mg/850 mg or 50 mg/1000 mg film-coated tablet twice daily.
If you have reduced kidney function, your doctor may prescribe a lower dose. Your doctor may also prescribe a lower dose if you are taking a known diabetes medicine such as a sulfonylurea.
Your doctor may prescribe this medication alone or together with certain medications that lower your blood sugar level.
How to use Eucreas
Swallow the tablets whole with a glass of water. Take one tablet in the morning and one in the evening with or after meals. Taking the tablet after meals will decrease the risk of digestive discomfort.
Follow your doctor's dietary advice. In particular, if you follow a diet for weight control in diabetics, continue the diet while taking Eucreas.
Side effects & precautions
Like all medicines, this diabetes treatment medication can cause side effects, although not everybody gets them.
You should stop taking Eucreas and see your doctor immediately if you experience any of the following side effects:
Lactic acidosis (very rare: may affect up to 1 user in 10,000):
- Eucreas can cause a very rare, but very serious side effect, called lactic acidosis. If this happens to you, you should stop taking Eucreas and contact a doctor or the nearest hospital immediately, as lactic acidosis can lead to a coma.
- Angioedema (rare: may affect up to 1 in 1,000 people): symptoms including a swollen face, tongue or throat, difficulty swallowing, difficulty breathing, a sudden onset of a rash or hives, which may be indicative of a reaction called "angioedema" .
- Liver disease (hepatitis) (rare): Symptoms including yellowing of the skin and eyes, nausea, loss of appetite, or dark discoloration of the urine, which may be indicative of liver disease (hepatitis).
- Inflammation of the pancreas (pancreatitis) (frequency not known): Symptoms including severe and persistent pain in the abdomen (stomach area), which can reach your back, as well as nausea and vomiting.
Other adverse effects
Some patients have experienced the following side effects while taking Eucreas:
- Very common (may affect more than 1 in 10 people): nausea, vomiting, diarrhea, pain in the stomach area (abdominal pain), loss of appetite.
- Common (may affect up to 1 in 10 people): dizziness, headache, uncontrolled tremor, metallic taste, decreased blood glucose.
- Uncommon (may affect up to 1 in 100 people): swollen joint pain, fatigue, constipation, swollen hands, ankles, or feet (edema).
- Very rare (may affect up to 1 in 10,000 people): sore throat, nasal congestion, and fever; signs of having a high level of lactic acid in the blood (known as lactic acidosis) such as drowsiness or dizziness, vomiting, and severe nausea, abdominal pain, irregular heartbeat, or deep, fast breathing; redness of the skin, itching; decreased vitamin B12 levels (paleness, tiredness, mental symptoms such as confusion or memory disturbances).
Some patients have experienced the following side effects while taking Eucreas and a sulfonylurea:
- Common: dizziness, tremor, weakness, low blood glucose levels, excessive sweating.
Some patients have had the following side effects while taking Eucreas and insulin:
- Common: headache, chills, nausea (malaise), low blood glucose levels, heartburn.
- Uncommon: diarrhea, flatulence.
Since the marketing of this product, the following side effects have also been reported:
- Frequency not known (cannot be estimated from the available data): an itchy rash, inflammation of the pancreas, localized peeling of the skin or blisters, muscle pain.
Buying Eucreas online
You can buy eucreas tablets online through one of the UK’s leading online pharmacies, Pharmacy Planet. It's easy and convenient. You will need to fill out a short assessment and the item will be delivered directly to your door. If you want to buy diabetes medication online, use Pharmacy Planet, a UK pharmacy you can trust.
Eucreas is used to treat adult patients with type 2 diabetes. This type of diabetes is also known as non-insulin-dependent diabetes mellitus. Type 2 diabetes occurs if the body does not make enough insulin or if the insulin produced does not work properly. It can also appear if the body produces too much glucagon. Insulin and glucagon are produced in the pancreas. Insulin helps reduce blood sugar levels, especially after meals. Glucagon promotes sugar production by the liver and causes blood sugar levels to rise.
Eucreas combines two antidiabetic drugs with complementary mechanisms of action to improve glycemic control in patients with type 2 diabetes: vildagliptin, a member of the group of pancreatic islet enhancers, and metformin hydrochloride, a member of the biguanide group.
Vildagliptin, a member of the pancreatic islet enhancers group, is a potent and selective inhibitor of dipeptidyl peptidase 4 (DPP-4). Metformin works mainly by decreasing endogenous hepatic glucose production.
Eucreas uses includes being indicated in the treatment of type 2 diabetes mellitus:
- Eucreas is indicated for the treatment of adult patients who are unable to achieve sufficient glycemic control with the maximum tolerated dose of metformin as oral monotherapy or who are already being treated with the combination of vildagliptin and metformin in individual tablets.
- Eucreas is indicated in combination with a sulfonylurea (i.e. triple combination therapy) as an adjunct to diet and exercise in inadequately controlled adult patients with metformin and a sulfonylurea.
- Eucreas is indicated in triple combination therapy with insulin as an adjunct to diet and exercise to improve glycemic control in adult patients in whom a stable dose of insulin and metformin alone does not provide adequate glycemic control.
The dose of Eucreas that each person should take varies depending on their state. Your doctor will tell you exactly how much Eucreas to take.
Always use this medicine exactly as your doctor has told you. If in doubt, consult your doctor or pharmacist again.
The recommended eucreas tablets dosage is one 50 mg/850 mg or 50 mg/1000 mg film-coated tablet twice daily.
If you have reduced kidney function, your doctor may prescribe a lower dose. Your doctor may also prescribe a lower dose if you are taking a known diabetes medicine such as a sulfonylurea.
Your doctor may prescribe this medication alone or together with certain medications that lower your blood sugar level.
How to use Eucreas
Swallow the tablets whole with a glass of water. Take one tablet in the morning and one in the evening with or after meals. Taking the tablet after meals will decrease the risk of digestive discomfort.
Follow your doctor's dietary advice. In particular, if you follow a diet for weight control in diabetics, continue the diet while taking Eucreas.
Like all medicines, this diabetes treatment medication can cause side effects, although not everybody gets them.
You should stop taking Eucreas and see your doctor immediately if you experience any of the following side effects:
Lactic acidosis (very rare: may affect up to 1 user in 10,000):
- Eucreas can cause a very rare, but very serious side effect, called lactic acidosis. If this happens to you, you should stop taking Eucreas and contact a doctor or the nearest hospital immediately, as lactic acidosis can lead to a coma.
- Angioedema (rare: may affect up to 1 in 1,000 people): symptoms including a swollen face, tongue or throat, difficulty swallowing, difficulty breathing, a sudden onset of a rash or hives, which may be indicative of a reaction called "angioedema" .
- Liver disease (hepatitis) (rare): Symptoms including yellowing of the skin and eyes, nausea, loss of appetite, or dark discoloration of the urine, which may be indicative of liver disease (hepatitis).
- Inflammation of the pancreas (pancreatitis) (frequency not known): Symptoms including severe and persistent pain in the abdomen (stomach area), which can reach your back, as well as nausea and vomiting.
Other adverse effects
Some patients have experienced the following side effects while taking Eucreas:
- Very common (may affect more than 1 in 10 people): nausea, vomiting, diarrhea, pain in the stomach area (abdominal pain), loss of appetite.
- Common (may affect up to 1 in 10 people): dizziness, headache, uncontrolled tremor, metallic taste, decreased blood glucose.
- Uncommon (may affect up to 1 in 100 people): swollen joint pain, fatigue, constipation, swollen hands, ankles, or feet (edema).
- Very rare (may affect up to 1 in 10,000 people): sore throat, nasal congestion, and fever; signs of having a high level of lactic acid in the blood (known as lactic acidosis) such as drowsiness or dizziness, vomiting, and severe nausea, abdominal pain, irregular heartbeat, or deep, fast breathing; redness of the skin, itching; decreased vitamin B12 levels (paleness, tiredness, mental symptoms such as confusion or memory disturbances).
Some patients have experienced the following side effects while taking Eucreas and a sulfonylurea:
- Common: dizziness, tremor, weakness, low blood glucose levels, excessive sweating.
Some patients have had the following side effects while taking Eucreas and insulin:
- Common: headache, chills, nausea (malaise), low blood glucose levels, heartburn.
- Uncommon: diarrhea, flatulence.
Since the marketing of this product, the following side effects have also been reported:
- Frequency not known (cannot be estimated from the available data): an itchy rash, inflammation of the pancreas, localized peeling of the skin or blisters, muscle pain.
You can buy eucreas tablets online through one of the UK’s leading online pharmacies, Pharmacy Planet. It's easy and convenient. You will need to fill out a short assessment and the item will be delivered directly to your door. If you want to buy diabetes medication online, use Pharmacy Planet, a UK pharmacy you can trust.
Eucreas can help control blood sugar levels through the two active ingredients present within the medicine – vildagliptin and metformin. Metformin is responsible for reducing the amount of glucose produced by the liver and increasing insulin sensitivity. Vildagliptin can enhance insulin production within the body in response to food consumption. This dual-action mechanism makes Eucreas effective at stabilising blood glucose levels and helps prevent sugar spikes after eating meals.
To make the most of Eucreas for diabetes, you should use it in accordance with your healthcare professional’s directions. The usual instructions for Eucreas are to take it once or twice daily with meals; however, this can depend on the severity of your condition, your blood sugar levels, and any additional needs you may have as part of your treatment plan.
Yes, Eucreas can be used with other diabetes medicines, like insulin or additional oral diabetes medications, so long as this is prescribed as a treatment plan by your healthcare professional. A combination of diabetes medicines may help to improve blood sugar control if you feel like your current medicine cannot do this alone. However, you should keep a close eye on your blood glucose levels and monitor any changes in case hypoglycaemia occurs. Always discuss any issues, possible changes to treatment and questions with your healthcare professional so they can determine what works best for you.
Some potential side effects of Eucreas are gastrointestinal issues, such as sickness, diarrhoea, or stomach upset. These symptoms may occur when first starting the medication but often improve as your body adjusts. Some individuals have also reported experiencing headaches and a metallic taste in the mouth. A more serious side effect could be hypoglycaemia, especially if Eucreas is used in combination with other medicines. Monitor your blood sugar levels and report any side effects to your healthcare provider.
Alcohol can affect blood sugar levels. When using Eucreas while consuming alcohol, you may be more susceptible to hypoglycaemic episodes. Avoid drinking excessively and monitor your blood sugar levels closely to detect any irregularities.
If you have kidney problems, you should exercise caution when using or considering the use of Eucreas. Vildagliptin and metformin can both have adverse effects on the kidneys, particularly in individuals with a history of kidney issues. Your healthcare professional should assess your kidney function before prescribing this medicine and may recommend alternative therapies if necessary.

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Authored By
HARMINDER ‘HARMY’ KAUR
BSc(hons) Pharmacy
GPhC Number: 2061107

Reviewed By
GURDEV SEHMI
BSc Pharm, MRPharmS, Independent Prescriber, Superintendent Pharmacist, Clinical Lead
GPhC Number: 2050925














