Trusopt (Dorzolamide) eye drop solution is a medicine used for the treatment of open-angle glaucoma and ocular hypertension. Its mechanism ...

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About Trusopt

Trusopt (Dorzolamide) eye drop solution is a medicine used for the treatment of open-angle glaucoma and ocular hypertension. Its mechanism of action is the inhibition of carbonic anhydrase. The main active ingredient in Trusopt, Dorzolamide, irreversibly inhibits carbonic anhydrase at the level of the ciliary processes of the eye, which decreases the secretion of aqueous humor, probably by decreasing the formation of bicarbonate ions with the subsequent reduction of sodium and fluid transport. Your doctor will determine the appropriate dosage and duration of treatment. In the case of using it alone, the dose is 1 drop in the affected eye (s), in the morning, in the afternoon, and at night.

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What is Trusopt?

Trusopt (Dorzolamide) eye drop solution is a medicine used for the treatment of open-angle glaucoma and ocular hypertension. Its mechanism of action is the inhibition of carbonic anhydrase. It is used in the form of eye drops that are instilled directly on the conjunctiva of the eye. It can be used in association with other medications and there are presentations in which it is mixed with timolol, which is another drug that is also used in ocular hypertension but works through a different mechanism.

How does it work?

The main active ingredient in Trusopt, Dorzolamide, irreversibly inhibits carbonic anhydrase at the level of the ciliary processes of the eye, which decreases the secretion of aqueous humor, probably by decreasing the formation of bicarbonate ions with the subsequent reduction of sodium and fluid transport. It acts specifically against carbonic anhydrase II, an enzyme that is found in high concentrations in erythrocytes. When applied topically, it reaches the systemic circulation in significant proportions, accumulates in red blood cells after long-term therapy, and as a result of its irreversible binding to carbonic anhydrase II, has a long half-life (3.5 to 4 months). It is metabolized in the liver, where an active metabolite is formed, and excreted in the urine.

What are the benefits of taking it?

Trusopt contains dorzolamide which belongs to a group of medicines called "carbonic anhydrase inhibitors". Dorzolamide Eye drop uses include being indicated to lower high pressure in the eye and to treat glaucoma. This medication can be used alone or in combination with other medications that lower pressure in the eye (called beta-blockers)

How do I use it?

Do not use the container if the plastic safety strap around the neck of the container is missing or broken. When you open the container for the first time, tear off the plastic safety strip.

Every time you use Trusopt:

  1. Wash your hands.
  2. Open the container. Take special care to avoid the tip of the dropper container touching your eye, the skin around the eye, or your fingers.
  3. Tilt your head back and hold the bottle upside down over your eye.
  4. Pull the lower eyelid down and look up. Gently hold and squeeze the container on the flattened sides and drop one drop into the space between the lower eyelid and the eye.
  5. Press the end of your eye, next to the nose, or close your eyelids for about 2 minutes. This helps prevent the medicine from reaching the rest of the body.
  6. Repeat steps 3 through 5 with the other eye, if directed by your doctor.
  7. Replace the cap and close the container tightly.

Its dosage

Your doctor will determine the appropriate dosage and duration of treatment. In the case of using it alone, the dose is 1 drop in the affected eye (s), in the morning, in the afternoon, and at night. If your doctor has recommended the use of Trusopt with 1 drop of beta-blocker ophthalmic to decrease eye pressure, the dose is 1 drop of Trusopt in the affected eye (s) in the morning and at night. If you use Trusopt and another product in eye drops, you should allow at least 10 minutes to pass between them. Do not touch the eye or the surrounding parts with the tip of the dropper. To avoid possible contamination, prevent the dropper tip from touching any surface.

Side effects & precautions

Like all medicines, this medicine can cause side effects, although not everybody gets them.

If you develop allergic reactions such as hives, swelling of the face, lips, tongue and / or throat that can cause difficulty in breathing or swallowing, stop using this medicine and consult your doctor immediately.

Very common side effects: (may affect more than 1 in 10 people)

  • Burning and stinging of the eyes.

Common side effects: (may affect up to 1 in 10 people)

  • Corneal disease with eye pain and blurred vision (superficial dotted keratitis), itchy discharge from the eyes (conjunctivitis), irritation/inflammation of the eyelid, blurred vision, headache, nausea, bitter taste, and fatigue.

Uncommon side effects: (may affect up to 1 in 100 people)

  • Inflammation of the iris.

Rare side effects: (may affect up to 1 in 1,000 people)

  • Tingling or numbness of the hands or feet, transient myopia that remits when therapy ceases, development of fluid under the retina (choroidal detachment, after filtering surgery), eye pain, crusting of the eyelid, low pressure in the eye, inflammation of the cornea (with symptoms of visual disturbances), eye irritation including redness, kidney stones, dizziness, nosebleed, sore throat, dry mouth, localized skin rash (contact dermatitis), severe skin reactions, reactions allergic-type such as skin rash, hives, itching, in rare cases swelling of the lips, eyes and mouth, shortness of breath, and more rarely difficulty breathing.

Frequency not known: (cannot be estimated from the available data)

  • Shortness of breath, foreign body sensation in the eye (sensation of having something in the eye), and a pounding heartbeat that may be rapid or irregular (palpitations).

Buying Trusopt online.

You can buy Trusopt Dorzolamide Eye drop solution online through one of the UK’s leading online pharmacies, Pharmacy Planet. It's easy and convenient. You will need to fill out a short assessment and the item will be delivered directly to your door. If you want to buy Trusopt Dorzolamide Eye drops online, use Pharmacy Planet, a UK pharmacy you can trust.

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