Saflutan (Tafluprost) is indicated for the reduction of elevated intraocular pressure in patients with open-angle glaucoma and ocular hypertension. The ...

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About Saflutan

Saflutan eye drops solution contains tafluprost, which belongs to a group of medicines called prostaglandin analogs. Saflutan reduces eye pressure. It is used when the pressure inside the eye is too high. Tafluprost acid, metabolite biologically active tafluprost, is a highly potent and selective FP receptor agonist human prostanoid. The recommended dose is 1 drop of Saflutan in one or both eyes, once a day, at night. Do not instill more drops or use it more frequently than directed by your doctor as this can make Saflutan less effective.

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What is Saflutan?

Saflutan eye drops solution contains tafluprost, which belongs to a group of medicines called prostaglandin analogs. Saflutan reduces eye pressure. It is used when the pressure inside the eye is too high.

How does it work?

The main active ingredient, Tafluprost is a fluorinated analogue of prostaglandin F2α. Tafluprost acid, metabolite biologically active tafluprost, is a highly potent and selective FP receptor agonist human prostanoid. Tafluprost acid has a 12-fold higher affinity for the FP receptor than from latanoprost. Pharmacodynamic studies in monkeys indicate that tafluprost reduces the intraocular pressure by increasing uveoscleral outflow from the aqueous humor.

What are the benefits of taking it?

Saflutan is used to treat a type of glaucoma called open-angle, and also a condition is known as eye hypertension in adults. Both disorders are linked to increased pressure inside the eye and can eventually affect vision.

How do I use it and its dosage?

Always use this medicine exactly as your doctor or pharmacist has told you. If in doubt, consult your doctor or pharmacist again. The recommended dose is 1 drop of Saflutan in one or both eyes, once a day, at night. Do not instill more drops or use it more frequently than directed by your doctor as this can make Saflutan less effective.

Only use Saflutan in both eyes if your doctor tells you to.

For use as eye drops only. Do not ingest them in any other way.

Instructions for use:

When starting a new bag:

Do not use the single-dose containers if the bag is open. Open the bag along the dotted line. Write the date you opened the bag, in the space reserved for the date, on the bag.

  1. Wash your hands.
  2. Remove the packaging strip from the bag.
  3. Tear off a single-dose container from the strip
  4. Put the remaining strip back in the bag and fold the edge to close the bag.
  5. Make sure the solution is at the bottom of the single-dose container.
  6. To open the package, unscrew the tab.
  7. Tilt your head back.
  8. Place the tip of the container close to the eye.
  9. Pull the lower eyelid down and look up.
  10. Gently squeeze the container and drop a drop into the space between the lower eyelid and the eye.
  11. Close the eye for a moment and press your finger into the inner corner of the eye for about a minute. This helps prevent the drop from draining into the tear duct.
  12. Blot excess solution from the skin around the eye.

If a drop does not fall into the eye, try again.

Side effects & precautions

Like all medicines, this medicine can cause side effects, although not everybody gets them. Most of the side effects are not serious. The following section includes the known eye drops side effects and their frequency.

Frequent side effects

The following effects can affect up to 1 in 10 people:

Effects on the nervous system:

  • headache

Effects on the eyes:

  • itchy eyes
  • eye irritation
  • eye pain
  • red eyes
  • changes in length, thickness, and number of tabs
  • dry eyes
  • A feeling of having a foreign body in the eye
  • eyelash color change
  • redness of the eyelids
  • small areas of inflammation at points on the surface of the eye
  • light sensitivity
  • crying eyes
  • blurry vision
  • decreased visual ability to see details
  • iris color change (maybe permanent)

Uncommon side effects

The following effects can affect up to 1 in 100 people:

Effects on the eyes:

  • change in skin color around the eyes
  • swelling of the eyelids
  • tired eyes
  • swelling of the superficial membranes of the eye
  • crying eyes
  • inflammation of the eyelids
  • signs of inflammation inside the eye
  • eye discomfort
  • pigmentation of the superficial membranes of the eye
  • follicles on the superficial membranes of the eye
  • allergic inflammation
  • abnormal sensation in the eye

Effects on skin and tissues under the skin:

  • unusual growth of hair on the eyelids

Frequency not known: cannot be estimated from the available data

Effects on the eyes:

  • inflammation of the iris/uvea (central layer of the eye)
  • Hollow eyes
  • macular edema/cystoid macular edema (inflammation of the retina within the eye leading to worsening of vision).

Interactions

No interactions are anticipated in humans because systemic concentrations of tafluprost are extremely low after ophthalmic administration. Therefore, no studies have been conducted specific interaction between tafluprost and other drugs. In clinical trials, tafluprost was used concomitantly with timolol, not having been observed signs of interaction.

Warning and precautions

Before initiating treatment, patients should be informed of the possibility of growth of eyelashes, darkening of the skin of the eyelids, and increased pigmentation of the iris. Some of these changes can be permanent and can cause differences in the appearance of the eyes when it comes to only one of them.

The change in iris pigmentation occurs slowly and may not be evident for several months. The change in eye color has been observed predominantly in patients with different colors in the iris, for example, blue-brown, gray-brown, yellow-brown, and green-brown. The risk of heterochromia between the eyes in unilateral cases.

There is a possibility of hair growing in areas where tafluprost comes in contact with the surface of the skin repeatedly. There is no experience with tafluprost in neovascular, angle-closure, narrow-angle or congenital. There is only limited experience with tafluprost in aphakic patients and in pigmentary glaucoma or pseudoexfoliative.

Caution is recommended when using tafluprost in aphakic patients, in pseudophakic patients with tear of the posterior lens capsule or lens in the anterior chamber, or in patients with Proven risk factors for cystoid macular edema, iritis or uveitis.

Buying Saflutan online.

You can buy the Saflutan Eye Drop solution online through one of the UK’s leading online pharmacies, Pharmacy Planet. It's easy and convenient. You will need to fill out a short assessment and the item will be delivered directly to your door. If you want to buy these eye drops online, use Pharmacy Planet, a UK pharmacy you can trust.

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