DuoTrav is a clear solution eye drop. DuoTrav contains two active ingredients: travoprost (40 micrograms/ml) and timolol (5 mg/ml). It ...

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About Duotrav

DuoTrav is used to reduce intraocular pressure (the pressure inside the eye, short for IOP-IntraOcular Pressure). It is used in patients with open-angle glaucoma (a disease that causes the pressure inside the eye to rise due to the inability to drain fluid) and in patients with ocular hypertension (i.e., the pressure inside the eye above normal).DuoTrav contains two active ingredients: travoprost (40 micrograms/ml) and timolol (5 mg/ml). It is used in patients with open-angle glaucoma (a disease that causes the pressure inside the eye to rise due to the inability to drain fluid) and in patients with ocular hypertension (i.e., the pressure inside the eye above normal). The medicine can only be obtained with a prescription.

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What is Duotrav?

DuoTrav is used to reduce intraocular pressure (the pressure inside the eye, short for IOP-IntraOcular Pressure). It is used in patients with open-angle glaucoma (a disease that causes the pressure inside the eye to rise due to the inability to drain fluid) and in patients with ocular hypertension (i.e., the pressure inside the eye above normal). DuoTrav contains a combination of medications, a beta-blocker (timolol), and a prostaglandin analog (travoprost), and is used in patients who do not respond sufficiently to eye drops that contain only beta-blockers or only prostaglandin analogs.

How does it work?

Duotrav eye drop solution contains two active substances: Travoprost and Timolol Maleate. These two components lower the intraocular pressure through complementary mechanisms of action and the effect combined produces an additional reduction in IOP compared to each of the components separately.

Travoprost, an analogue of prostaglandin F2a, is a very complete agonist. selective having a high affinity for the PF receptor of prostaglandins and reduces intraocular pressure by increasing drainage of aqueous humor through the trabecular meshwork and uveoscleral route. The reduction of IOP in humans starts within approximately 2 hours after administration and the maximum effect is reached after 12 hours. You can keep a significant reduction in intraocular pressure with a single dose during periods longer than 24 hours.

Timolol is a non-selective adrenergic blocking agent that lacks intrinsic sympathomimetic activity, the direct depressant activity of the myocardium, or membrane-stabilizing activity. Human studies with tomography and fluorophotometry suggest that its predominant action is related to reduced aqueous humor formation and a slightly increased outflow.

What are the benefits of taking it?

DuoTrav is used to reduce intraocular pressure. It is used in adult patients who have "open-angle glaucoma" or "ocular hypertension" who do not respond sufficiently to eye drops containing beta-blockers or prostaglandin analogues (other drugs used for these conditions).

Intraocular pressure means that the pressure inside the eye is higher than normal. In open-angle glaucoma, the pressure increases because the eye does not drain enough fluid.

How do I use it?

The recommended dose is one drop in the affected eye (s) or eye (s), once-daily - morning or evening. Use it at the same time each day. DuoTrav should only be applied to both eyes if your doctor has recommended it.

  1. Immediately before using a bottle for the first time, open the wrapping bag, remove the bottle, and write the opening date in the space provided on the
  2. Stand before a mirror
  3. Wash your hands
  4. Unscrew the cap on the bottle
  5. Hold the bottle upside down between your fingers
  6. Tilt your head back. Gently separate the lower eyelid from the eye with a finger, until a bag forms, into which the drop should fall
  7. Bring the dropper tip close to the eye. The mirror may be helpful
  8. Do not touch the eye, eyelid, proximal areas, or other surfaces with the dropper, as the drops could become infected
  9. Gently squeeze the bottle so that one drop of DuoTrav falls each time. If a drop falls out of the eye, try again
  10. After using DuoTrav, press the edge of the eye, next to the nose, for 2 minutes. This helps prevent DuoTrav from passing to the rest of the body
  11. If DuoTrav is to be applied to both eyes, repeat the above steps on the other eye
  12. Close the bottle tightly immediately after using the product
  13. Use only one bottle at a time. Do not open the bag until you need to use the bottle

Its dosage

Use in adults, including elderly patients

The dose is one drop of DuoTrav into the conjunctival sac of the affected eye (s) once daily in the morning or evening. It must be administered every day at the same time.

If a dose is missed, treatment should be continued with the next dose as planned. The dose should not exceed one drop daily in the affected eye (s).

Special populations

Liver and kidney failure

No studies with DuoTrav or timolol 5 mg/ml eye drops have been performed in patients with hepatic or renal impairment.

Travoprost has been studied in patients with mild to severe hepatic impairment and in patients with mild to severe renal impairment (creatinine clearance as low as 14 ml/min). No dose adjustment was necessary for these patients.

Patients with hepatic or renal impairment are unlikely to require a dose adjustment with DuoTrav

Pediatric population

The safety and efficacy of DuoTrav in children and adolescents under 18 years of age have not been established. There is no available data.

Side effects & precautions

Like all medicines, this medicine can cause side effects, although not everybody gets them.

In general, unless the effects are severe, you can continue to use the eye drops. If these effects concern you, ask your doctor or pharmacist. Do not stop applying DuoTrav without consulting your doctor.

Very common side effects (may affect more than 1 in 10 people)

  • Effects on the eye
  • Redness of the

Common side effects (may affect up to 1 in 10 people)

  • Effects on the eye
  • Inflammation with damage to the surface of the eye, eye pain, blurred vision, abnormal vision, dry eye, itchy eyes, eye discomfort, signs and symptoms of eye irritation (eg burning, stitching).

Uncommon side effects (may affect up to 1 in 100 people)

  • Effects on the eye
  • Inflammation of the surface of the eye, inflammation of the eyelid, swelling of the conjunctiva, increased growth of the eyelashes, inflammation of the iris, inflammation of the eye, sensitivity to light, decreased vision, tired eyesight, eye allergy, swelling in the eye, increased tear production, redness of the eyelid, eyelid discoloration, darkening of the skin (around the eye).

Other effects

  • Allergic reaction to the active substance, dizziness, headache, increased or decreased blood pressure, shortness of breath, excessive hair growth, dripping in the back of the throat, inflammation and itchy skin, decreased heart rate

Rare side effects (may affect up to 1 in 1,000 people)

  • Effects on the eye
  • Thinning of the surface of the eye, inflammation of the eyelid glands, ruptured blood vessel in the eye, crusting of the eyelid, abnormal growth, and positioning of the eyelashes.

Other effects

  • Nervousness, irregular heart rate, hair loss, voice disorders, shortness of breath, cough, sore throat, hives, abnormal kidney blood test values, skin discoloration, thirst, tiredness, strange feeling inside the nose, colored urine, pain in hands and

Buying Duotrav online.

You can buy Duotrav eye drop online through one of the UK’s leading online pharmacies, Pharmacy Planet. It's easy and convenient. You will need to fill out a short assessment and the item will be delivered directly to your door. If you want to buy Duotrav eye drop solution online, use Pharmacy Planet, a UK pharmacy you can trust.

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