Azopt/Brinzolamide

Azopt ophthalmic is used in the treatment of elevated pressure in the eye in patients with open-angle glaucoma or ocular hypertension. The main active ingredient, brinzolamide is a carbonic anhydrase inhibitor. It works by reducing the production of fluids in the eye, thus helping to reduce intraocular pressure. Azopt is administered in the form of a solution for ophthalmic use, instilling in the eye as an eye drop.

It works by inhibiting carbonic anhydrase, which decreases the production of aqueous humor by ciliary processes. The disturbed balance between the production and reabsorption of aqueous humor is​ the main factor involved in ocular hypertension and glaucoma, a disease that can lead to permanent vision loss if left untreated.

After its administration in the form of eye drops, the fundamental action is local. Although it passes into the blood, its plasma concentration is very low and practically undetectable. Oral administration is theoretically feasible but is not used due to irregular absorption and a greater number of side effects.

Azopt (Brinzolamide) can be used as a single agent or in association with other drugs such as timolol, which also reduces ocular hypertension, but through a different mechanism of action.

Azopt is used to reduce intraocular pressure. It is indicated in patients with ocular hypertension (when the pressure in the eye is higher than normal) or open-angle glaucoma (a disease in which the eye pressure rises due to reduced drainage from the eye). Azopt is used as a complementary therapy to beta-blockers or prostaglandin analogues (other medicines used in these cases) or as monotherapy in patients who can take or have not responded to beta-blockers.

Always use this medicine exactly as your doctor or pharmacist has told you. If in doubt, consult your doctor or pharmacist again.

Only use AZOPT in your eye (s). Do not swallow or inject.

1. Take the AZOPT bottle and stand in front of a mirror
2. Wash your hands
3. Shake the bottle and unscrew the cap. After removing the cap, the seal ring should be removed if it is loose before using this medicine.
4. Hold the bottle upside down between your thumb and middle finger
5. Tilt your head back. Gently separate the eyelid from the eye with a finger, until a bag forms, into which the drop should fall.
6. Bring the tip of the bottle close to the eye. Can help with the mirror
7. Do not touch the eye, eyelid, proximal areas or other surfaces with the dropper, as the drops could become contaminated
8. Gently press the base of the bottle so that one drop of AZOPT falls each time.
9. Do not squeeze the bottle: it is designed so that gentle pressure on the base is sufficient.
10. After using AZOPT, press the edge of the eye, next to the nose with your finger for at least 1 minute. This helps prevent AZOPT from passing to the rest of the body.
11. If drops are applied to both eyes, repeat all of the above steps with the other eye
12. Screw the cap tightly on the bottle immediately after using the product.
13. Finish the bottle you are using before opening the next one.

If a drop falls out of the eye, try again.

If you are using another eye drop, wait at least 5 minutes between applying AZOPT and the other drops. Ophthalmic ointments should be administered last.

The dosage of Azopt is one drop in the affected eye or eyes twice a day. Some patients may have a better response by administering one drop three times a day. It is necessary to shake the suspension before use.

The use of Azopt is not recommended in patients with liver disease, given the lack of information on the safety and efficacy of the medicine in this category of patients. It should also not be administered to patients with severe renal impairment. Adequate experience in the pediatric use of Azopt has not been collected.

Like all medicines, this medicine can cause side effects, although not everybody gets them.

The following side effects have been observed with AZOPT

Frequent side effects (may affect up to 1 in 10 people).

• Effects in the eye (blurred vision, irritation in the eye, pain in the eye, discharge from the eye, itchy eye, dry eye, abnormal sensation in the eye, redness of the eye).
• Bad taste.

Uncommon side effects (may affect up to 1 in 100 people).

• Effects in the eye: sensitivity to light, inflammation or infection of the conjunctiva, eye swelling, itching, redness or swelling of the eyelid, deposits in the eye, glare, burning sensation, lump on the surface of the eye, increased pigmentation eye, tired eyesight, crusting on the eyelid, increased tear production.
• Decreased or decreased heart function
• Fast or irregular heartbeat
• Decreased heart rate
• Shortness of breath, shortness of breath
• pain
• Movement problems
• Decreased sexual behavior
• Male sexual problems
• Cold symptoms
• Chest congestion
• Sinus infection
• Sore throat
• Abnormal or decreased perception of stimuli in the mouth
• Inflammation of the lining of the esophagus
• Abdominal pain
• Nausea
• Vomiting
• Stomach pain
• Muscle pain and muscle spasms
• Back pain
• Nosebleeds

Rare side effects (may affect up to 1 in 1,000 people).

• Effects in the eye: swelling of the cornea, double or reduced vision, abnormal vision, flashes of light in the field of vision, decreased eye sensitivity, swelling around the eye, increased pressure in the eye, damage to the optic nerve.
• Other effects: memory loss, drowsiness, chest pain, upper respiratory tract congestion, sinus congestion, nasal congestion, dry nose, ringing in the ears, hair loss, general itching, feeling restless, irritability, irregular heart rate, general weakness, difficulty sleeping, wheezing, itchy rash.

You can buy Azopt online through one of the UK’s leading online pharmacies, Pharmacy Planet. It's easy and convenient. You will need to fill out a short assessment and the item will be delivered directly to your door. If you want to buy Azopt online, use Pharmacy Planet, a UK pharmacy you can trust.