Sevikar

Sevikar HCT contains three active substances called olmesartan medoxomil, amlodipine (as amlodipine besylate), and hydrochlorothiazide. All three substances help control high blood pressure.

Olmesartan medoxomil belongs to a group of medicines called 'angiotensin II receptor antagonists', which lower blood pressure by relaxing the blood vessels.

Amlodipine belongs to a group of medicines called "calcium channel blockers". Amlodipine also lowers blood pressure by relaxing the blood vessels.

Hydrochlorothiazide belongs to a group of medicines called thiazide diuretics. It lowers blood pressure contributing to the elimination of excess fluids, increasing the production of urine by the kidneys.

Sevikar HCT is a combination of an angiotensin II receptor antagonist, olmesartan medoxomil, a calcium channel blocker, amlodipine besylate, and a thiazide diuretic, hydrochlorothiazide. The combination of these components has an additive antihypertensive effect, lowering blood pressure to a greater degree than each component separately.

Sevikar HCT is used to treat high blood pressure:

• in adult patients whose blood pressure is not adequately controlled with the combination of olmesartan medoxomil and amlodipine, taken as a fixed-dose combination, or
• in patients who are already taking a fixed-dose combination of olmesartan medoxomil and hydrochlorothiazide, together with tablets containing only amlodipine, or a fixed-dose combination of olmesartan medoxomil and amlodipine, together with tablets containing only hydrochlorothiazide.

Always use the Sevikar medication exactly as your doctor or pharmacist has told you. If in doubt, consult your doctor or pharmacist again.

The recommended dose of Sevikar HCT is one tablet per day. The tablets can be taken with or without food. Take the tablets with a little liquid (such as a glass of water). The tablet should not be chewed. Do not take the tablets with grapefruit juice. If possible, take your daily dose at the same time each day, for example at breakfast time.

If you take more Sevikar HCT than you should

If you take more tablets than you should take, you will probably experience a drop in blood pressure, accompanied by symptoms such as dizziness, and a slow or fast heartbeat.

If you take more tablets than you should take, or if a child accidentally swallows a tablet, contact your doctor immediately or go to the nearest emergency room.

Like all medicines, these high blood pressure tablets can cause side effects, although not everybody gets them. If these occur, they are often mild and do not require stopping treatment.

The following two side effects can be serious, even if they affect only a small group of people:

During treatment with Sevikar HCT, allergic reactions can occur with inflammation of the face, mouth, and/or larynx (vocal cords), along with itching and skin rash. If this happens to you, stop taking Sevikar HCT and contact your doctor immediately.

Sevikar HCT can produce a pronounced drop in blood pressure in susceptible patients. This can cause severe light-headedness or light-headedness. If this happens to you, stop taking Sevikar HCT, see your doctor immediately and lie flat.

Sevikar HCT is a combination of three active substances. The following information firstly describes the side effects reported so far with the Sevikar HCT combination (in addition to those already mentioned) and secondly the known side effects of each of the active substances separately, or when two of the substances are taken together.

To give you an idea of ​​the number of patients that may have adverse effects, they have been classified as frequent, infrequent, rare, and very rare.

These are other side effects known so far with Sevikar HCT:

If these effects occur, they are often mild and you do not need to stop treatment.

Frequent sevikar side effects (may affect up to 1 in 10 people)

• Upper respiratory tract infection, sore throat, and nose, urinary tract infection, dizziness, headache, perception of heartbeat, low blood pressure, nausea, diarrhea, constipation, cramps, joint swelling, feeling of urgency urination, weakness, ankle swelling, tiredness, abnormal laboratory test values.

Infrequent sevikar side effects (may affect up to 1 in 100 people)

• Dizziness upon rising, vertigo, rapid heartbeat, fainting, redness, and warm feeling on the face, cough, dry mouth, muscle weakness, inability to have or maintain an erection.

These are the known adverse effects for each of the active substances separately or when two of the substances are taken together:

They can be side effects due to Sevikar HCT, even if they have not been seen so far with Sevikar HCT.

Very frequent sevikar side effects (may affect more than 1 in 10 people)

• Edema (fluid retention).

Frequent sevikar side effects (may affect up to 1 in 10 people)

• Bronchitis, stomach, and intestinal infection, vomiting, increased blood sugar, urine sugar, confusion, drowsiness, visual disturbances (including double vision and blurred vision), runny or stuffy nose, sore throat, shortness of breath, cough, abdominal pain, heartburn, upset stomach, flatulence, joint or bone pain, back pain, bone pain, blood in urine, flu-like symptoms, chest pain, pain.

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