Doxazosin is a drug indicated for the treatment of high blood pressure (hypertension) and benign prostatic hyperplasia (BPH). Doxazosin can be used in patients with BPH, whether they are hypertensive or normotensive. While changes in blood pressure in normotensive patients with BPH are clinically insignificant, patients who meet both conditions, HBP and BPH, can be effectively treated.
Doxazosin uses include being indicated in the treatment of hypertension and can be used as initial therapy to control blood pressure in most patients. In patients who are not adequately controlled with a single antihypertensive drug, doxazosin can be used alone or in combination with a thiazide diuretic, a beta-blocker, a calcium antagonist, or an angiotensin-converting enzyme (ACE) inhibitor
Always use this medicine exactly as your doctor has told you. If in doubt, ask your doctor or pharmacist.
This treatment has been indicated by your doctor specifically for you and your process. The dose will be established by the doctor depending on the needs of each patient. Depending on the individual response, the doctor may modify the doxazosin dosage. Faithfully follow your doctor's instructions regarding dosage and how to use it. Doxazosin can be administered both in the morning and at night.
Arterial hypertension
Doxazosin is administered orally. The usual dose is 2-4 mg once a day. It is recommended to start treatment with the administration of 1 mg once a day, for 1 or 2 weeks. Depending on the response of each patient, the dose can be increased to 2 mg, 4 mg, 8 mg or 16 mg daily as a maximum dose, at intervals of 1 or 2 weeks between them, until the desired reduction in the patient's blood pressure is achieved.
Doxazosin can be taken with other medications that your doctor has prescribed for the treatment of high blood pressure.
Benign prostatic hyperplasia
Doxazosin is administered orally. The usual dose is 2-4 mg once a day. It is recommended to start treatment with the administration of 1 mg once a day. Depending on the response of each patient, the dose can be increased to 2 mg, 4 mg or 8 mg daily as the maximum dose
Like all medicines, these blood pressure tablets can have side effects, although not everyone gets them.
The doxazosin side effects are mainly due to the pharmacological properties of the preparation. Most side effects are transient or will be tolerated throughout continued treatment.
Common (<1%): tiredness/nausea, fatigue, headache, chest pain, drowsiness, vertigo, postural vertigo, dizziness, edema, palpitations, muscle cramps, constipation, dyspepsia, respiratory distress, nasal congestion, delayed ejaculation, apathy, frequent need to urinate, increased urination, problems with accommodation.
Uncommon: general/facial edema, syncope, facial flushing, fever/chills, paleness, postural hypotension, arrhythmia, peripheral ischemia, angina pectoris, tachycardia, myocardial infarction, tremors, muscle weakness, anorexia, increased appetite, alopecia, epistaxis, bronchospasm, cough, pharyngitis, thirst, hypokalemia, gout, muscle aches, swelling/joint pain, muscle weakness, nightmares, memory loss, emotional instability, incontinence, urinary disorders, dysuria, abnormal eye flow, photophobia, tinnitus, disorders of the sense of taste.
Rare: may affect up to 1 in 1,000: cerebrovascular disorders, depression, agitation, paresthesia, laryngeal edema, rash, itching, purpura, stomach pain, diarrhea, vomiting, jaundice, increased liver enzymes, hypoglycemia, blurred vision, impotence, priapism, dysgeusia, drop in body temperature in elderly patients.
Very rare: persistent and painful erection of the penis. Consult a doctor urgently.
Single cases: Increased BUN and creatinine, decreased erythrocytes, leukocytes, and thrombocytes, postural hypotension, and, in rare cases, syncope at the start of treatment, especially at too high doses, but may also occur if therapy is resumed after discontinuation during a short space of time.
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