Eprosartan Tablets

Eprosartan tablets are a prescription medicine used to treat high blood pressure, also known as hypertension, in adults. Managing blood pressure effectively is one of the most important steps a person can take to protect their heart and reduce the risk of serious complications such as stroke, heart attack, and kidney disease.

Eprosartan belongs to a class of medicines called angiotensin receptor blockers (ARBs), which work by relaxing and widening blood vessels so that the heart does not have to work as hard to pump blood around the body. Pharmacy Planet supports patients in accessing regulated, clinically appropriate care through our online consultation service, where a registered prescriber will assess whether eprosartan is suitable for you as an individual.

Eprosartan tablets are an antihypertensive medication licensed in the United Kingdom for the treatment of essential hypertension in adults. Essential hypertension means high blood pressure that does not have a single identifiable cause. The medicine is available in three strengths: 300 mg, 400 mg, and 600 mg.

Eprosartan belongs to a group of medicines known as angiotensin receptor blockers, often abbreviated to ARBs. This group also includes medicines such as losartan, valsartan, and irbesartan. ARBs are a well-established class of antihypertensive medication and are recommended in national guidelines including those published by the National Institute for Health and Care Excellence (NICE) and the British National Formulary (BNF).

High blood pressure rarely causes noticeable symptoms, which is why it is sometimes called a silent condition. Left untreated over time, persistently raised blood pressure puts strain on the heart, arteries, brain, and kidneys. Effective blood pressure control with a medicine such as eprosartan, alongside appropriate lifestyle changes, can significantly reduce these long-term risks.

Eprosartan works by selectively blocking angiotensin II type 1 (AT1) receptors. To understand what this means for your blood pressure, it helps to know a little about how your body regulates blood vessel tension.

The renin-angiotensin-aldosterone system (RAAS) is a hormonal pathway that plays a central role in blood pressure regulation. Within this system, a hormone called angiotensin II acts on AT1 receptors found in blood vessel walls and the adrenal glands. When angiotensin II binds to these receptors, it causes blood vessels to narrow (vasoconstriction) and prompts the body to retain sodium and water, both of which raise blood pressure.

Eprosartan attaches to AT1 receptors and blocks angiotensin II from binding to them. This prevents the vasoconstrictive effect, allowing blood vessels to relax and widen. The result is a reduction in peripheral vascular resistance and a corresponding fall in blood pressure. Unlike ACE inhibitors, another class of antihypertensive medication, ARBs such as eprosartan do not cause a build-up of bradykinin. This means the dry, persistent cough that is a common side effect of ACE inhibitors is much less likely to occur with eprosartan.

For patients who cannot tolerate ACE inhibitors due to cough or other reasons, an ARB such as eprosartan may be a clinically appropriate alternative, subject to prescriber assessment.

Always take eprosartan exactly as your prescriber has directed. Read the Patient Information Leaflet supplied with your medicine before you start taking it and refer to it if you have any questions.

Eprosartan tablets are taken orally. You can take them with or without food. Swallow the tablet whole with a glass of water. Do not crush, chew, or split the tablets.

Try to take eprosartan at the same time each day. This helps to maintain a consistent level of the medicine in your body and supports effective blood pressure control. If you forget a dose, take it as soon as you remember unless it is nearly time for your next dose. In that case, skip the missed dose and continue with your usual schedule. Do not take a double dose to make up for a forgotten one.

Do not stop taking eprosartan suddenly without speaking to your prescriber first. Stopping an antihypertensive medication abruptly can cause your blood pressure to rise again. Your prescriber will advise you on how to manage any changes to your treatment.

Eprosartan tablets are available from Pharmacy Planet in three strengths following a valid prescription: 300 mg, 400 mg, and 600 mg.

Eprosartan 600 mg

The usual starting dose of eprosartan for most adults is 600 mg once daily. Clinical studies referenced in the Summary of Product Characteristics (SmPC) indicate that 600 mg once daily provides the most consistent antihypertensive effect for the majority of patients.

Eprosartan 300 mg and 400 mg

Some patients may be initiated on or titrated to a lower dose. The 300 mg and 400 mg strengths allow prescribers to tailor the dose to an individual patient's response and tolerability. The maximum recommended daily dose is 800 mg. If blood pressure remains inadequately controlled on eprosartan alone, a prescriber may consider combining it with another antihypertensive agent, such as a thiazide diuretic. The decision on dose and any combination therapy rests entirely with the prescribing clinician based on an assessment of your individual circumstances.

Eprosartan is not currently licensed for use in children and adolescents under 18 years of age.

Like all medicines, eprosartan can cause side effects, although not everyone will experience them. The following information is based on the current UK SmPC for eprosartan. For a complete list of side effects, always refer to the Patient Information Leaflet supplied with your medicine.

Common Side Effects

These may affect up to 1 in 10 people:

• Dizziness
• Headache
• Fatigue
• Rhinitis (runny or blocked nose)
• Upper respiratory tract infections

Uncommon Side Effects

These may affect up to 1 in 100 people:

• Abdominal pain
• Diarrhoea
• Nausea
• Joint pain (arthralgia)
• Back pain
• Skin rash

Serious Side Effects — Seek Immediate Medical Attention

Stop taking eprosartan and seek emergency medical help immediately if you experience any of the following:

• Swelling of the face, lips, tongue, throat, hands, feet, or ankles (angioedema). This is a rare but serious allergic reaction.
• A sudden significant fall in blood pressure (hypotension), which may cause fainting - particularly in patients who are dehydrated or who take diuretics.
• Raised potassium levels (hyperkalaemia), which may cause muscle weakness or heart rhythm disturbances.
• Significant changes in kidney function.

If you experience any side effects not listed here, or if a listed side effect becomes severe or troublesome, contact your prescriber or pharmacist for advice.

Eprosartan May Be Suitable For Adults Who:

• Have been diagnosed with essential hypertension
• Cannot tolerate ACE inhibitors, for example due to a persistent cough
• Require blood pressure control as part of a wider cardiovascular therapy plan, as directed by their prescriber

Eprosartan Is Contraindicated In Patients Who:

• Are pregnant or planning to become pregnant. ARBs, including eprosartan, are contraindicated during pregnancy due to the risk of serious harm to the unborn baby. If you become pregnant while taking this medicine, contact your prescriber immediately.
• Are breastfeeding
• Have severe liver impairment
• Have a known hypersensitivity (allergy) to eprosartan or to any of the excipients listed in the SmPC
• Are taking aliskiren-containing medicines and have diabetes mellitus or renal impairment (eGFR below 60 mL/min/1.73 m2)

Use With Caution In Patients Who Have:

• Kidney impairment - regular monitoring of renal function and serum potassium is recommended
• Low blood volume or sodium levels (hypovolaemia or hyponatraemia)
• A history of angioedema
• Aortic or mitral stenosis
• Hypertrophic obstructive cardiomyopathy

Eprosartan may interact with other medicines. Tell your prescriber or pharmacist about all medicines you are currently taking, including over-the-counter products and herbal remedies. Particularly important interactions to report include:

• Potassium-sparing diuretics, potassium supplements, or potassium-containing salt substitutes, combination may raise blood potassium levels
• Non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen or naproxen, may reduce the blood pressure lowering effect of eprosartan and increase the risk of kidney problems
• Lithium, ARBs can increase lithium blood levels, which may cause toxicity
• Other antihypertensive medicines, additive blood pressure lowering effects should be monitored
• Dual blockade of the RAAS (for example, combining an ARB with an ACE inhibitor or aliskiren) is generally not recommended due to an increased risk of kidney failure, low blood pressure, and raised potassium levels

At Pharmacy Planet, our priority is your safety and clinical wellbeing. The consultation is the primary and essential step in this process. Requesting a consultation is not the same as receiving a prescription, and any prescription will only be issued if a registered prescriber independently determines that eprosartan is clinically appropriate for you specifically.

To begin, you will complete a detailed online health questionnaire. This gathers information about your medical history, current medicines, relevant measurements such as blood pressure readings, and other clinical factors that a prescriber needs in order to make a safe and informed decision.

A registered prescriber will then review your responses. They may ask follow-up questions or request additional information. If they determine that eprosartan is clinically appropriate for you, they will issue a prescription. If they do not consider it appropriate, they will let you know and may suggest that you seek further advice from your GP or another healthcare professional.

If a prescription is issued, your medicine is dispensed by our GPhC-registered pharmacy and dispatched in secure, discreet packaging. All prescribers working with Pharmacy Planet are registered with the General Medical Council (GMC) or Nursing and Midwifery Council (NMC) as appropriate.

• Store eprosartan tablets below 25 degrees Celsius in a dry place, away from direct sunlight and heat. Keep the tablets in their original packaging until you need to take them.
• Keep all medicines out of the sight and reach of children.
• Do not use eprosartan after the expiry date printed on the packaging. If your medicine has expired or you no longer need it, do not dispose of it in household waste or down the sink. Return unused or expired medicines to your local pharmacy for safe disposal.

The table below compares ARB tablets and Rasilez (aliskiren), the only direct renin inhibitor licensed for hypertension in the UK. All act on the renin-angiotensin-aldosterone system (RAAS) and are taken once daily as tablets.

Important: This comparison is for general information only and does not replace medical advice. A prescriber will decide which treatment is suitable for you following an online consultation.

Pharmacy Planet is a GPhC-registered online pharmacy committed to providing safe, regulated access to prescription medicines for patients across the United Kingdom. Our service is built around clinical governance, patient safety, and transparent, informative healthcare.

Our online consultation pathway is designed to replicate the clinical rigour of a face-to-face appointment. Every prescription is reviewed and issued by a registered clinician. Our dispensing team are qualified pharmacists and pharmacy technicians with access to full patient consultation records.

We offer a confidential, accessible service for patients who may find it difficult to attend a GP surgery in person, or who wish to supplement their existing NHS care with a convenient, regulated alternative. All consultations and dispensing take place within the framework of UK medicines law and GPhC guidance.

References

1. National Institute for Health and Care Excellence. Hypertension in adults: diagnosis and management. NICE guideline NG136. https://www.nice.org.uk/guidance/ng136. Accessed May 2026.
2. Joint Formulary Committee. British National Formulary (BNF). Eprosartan. https://bnf.nice.org.uk. Accessed May 2026.
3. Electronic Medicines Compendium. Tevaten 600 mg Film-coated Tablets — Summary of Product Characteristics. https://www.medicines.org.uk/emc. Accessed May 2026.
4. MHRA. Angiotensin-II receptor antagonists (sartans): risk of angioedema. Drug Safety Update, April 2017. https://www.gov.uk/drug-safety-update. Accessed May 2026.
5. NHS. High blood pressure (hypertension). https://www.nhs.uk/conditions/high-blood-pressure-hypertension. Accessed May 2026.