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Perindopril Tablets

Perindopril is a prescription medication used for high blood pressure (hypertension). It is an angiotensin-converting enzyme (ACE) inhibitor. It reduces the heart’s workload by widening blood vessels. Along with hypertension, Perindopril may be prescribed to treat heart failure or to protect blood vessels following a recent heart attack. Perindopril is available in 2 mg, 4 mg, and 8 mg strengths. These are oral tablets which must be swallowed with a glass of water. If you are looking to buy Perindopril tablets from Pharmacy Planet, then complete the online clinical questionnaire form, and the medication will be delivered to you once the order is approved by one of our prescribers.
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Perindopril Tablets
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Please note that whilst you are able to request the medicine strength and size required,
we will only be able to send on approval from our in house pharmacist.

Starts at £19.00
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Price Comparison

Select your preferred options and see the best price

PackPrice (£)
-2mg90 Tablets23.00
-2mg60 Tablets21.00
-2mg30 Tablets19.00
-4mg90 Tablets23.00
-4mg60 Tablets21.00
-4mg30 Tablets19.00
-8mg90 Tablets23.00
-8mg60 Tablets21.00
-8mg30 Tablets19.00

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What are Perindopril Tablets?

Perindopril is a medicine produced in the form of tablets for the long term treatment of hypertension (high blood pressure). The drug is included in the class of angiotensin-converting enzyme (ACE) inhibitors.

Perindopril is also prescribed to reduce the risk of heart-related complications if one suffers from coronary artery disease. These complications include conditions like stroke or heart attack. Taking Perindopril also improves the chances of survival of a patient after heart surgery or a heart attack. The drugs work by relaxing and widening up blood vessels which result in reduced blood pressure.  It prevents the release of some natural chemicals which not only improve the blood flow making it smoother but also tighten the blood vessels.

How Does Perindopril Work?

Perindopril works by improving the blood flow by preventing the production of some natural chemicals - helping the blood vessel to relax and widen up. This result in reduced blood pressure which makes it easier for your heart to pump blood around your body.

Perindopril is referred to as a nonsulfhydryl prodrug that pertains to the angiotensin-converting enzyme (ACE) inhibitor class of medications. The drug effectively reduces the symptoms of hypertension as it rapidly metabolizes in the liver actively. 

Perindoprilat is a strong, aggressive inhibitor of ACE, which is the enzyme that converts angiotensin I (ATI) to angiotensin II (ATII). ATII maintain the blood pressure and is a significant part of the renin-angiotensin-aldosterone system (RAAS).

Perindopril is effective to treat medium to moderate level complications through hypertension, reducing the risk of congestive heart failure, and to limit and minimise the cardiovascular risk of patients with high blood or post-myocardial infarction and stable coronary disease.

What Are the Benefits of Taking Perindopril?

Intake of Perindopril decreases morbidity and mortality by minimizing the risk of the onset of stroke, renal failure, and diabetes.

Perindopril is also prescribed to the patients suffering from more advanced versions of the cardiovascular continuum as it helps to improve long-term prognosis in coronary artery disease.

Perindopril also helps to reduces cardiac remodeling following myocardial infarction and improves patient symptoms and prognosis in diastolic heart failure. Current trial evidence confirms the clinical benefits of perindopril throughout the cardiovascular continuum, thus slowing the progression of cardiovascular disease and improving patient prognosis.

  • Control Blood Pressure
  • Reduce Cardiac remodeling following myocardial infarction
  • Improves symptoms and prognosis in diastolic heart failure
  • Helps the Blood Vessels Relax and widen up
  • Widens the Arteries and Veins
  • Improves the blood flow of the body

How Do I Use Perindopril?

Perindopril comes as an oral tablet usually prescribed for long-term treatment. When prescribed by the doctor it is better to complete the course as discontinuing in the middle of the course may lead to high blood pressure that can further result in a sudden stroke or cardiac arrest. Only use this medication in compliance with doctor’s prescription and do not alter your dosage on the basis of personal observations. If you feel you need to change the dosage, consult your doctor first.

The drug may not work as effectively as it should if the drugs are not taken on the suggested schedule by the doctor. In case of overdose, the drug may cause various side effects including imbalances in blood pressure, and high potassium levels. Perindopril can be taken with or without food and the tablet can be cut into half if needed.

Perindopril Dosage

Adults who are 18–64 years are usually prescribed to take 4 mg taken once per day. The quantity can vary as per the severity of the condition and symptoms. A typical dosage may lie between 4–8 mg taken once per day or split into two divided doses. This drug hasn’t been studied in children. It shouldn’t be used in people younger than 18 years.

Perindopril Precautions and Side Effects

Side Effects

Side Effects of the medication can be mild to strong varying as per the quantity of overdose. Symptoms that may arise in severe cases include dizziness, weakness, headaches, upset stomach, stomach pain, diarrhoea, cough, back pain.

Warnings

It should be used with caution by patients with a medical history of angioedema, high blood levels of potassium, kidney disease or dialysis, salt restrictive diet, liver disease or any related allergy.

High-Risk Groups

High-risk groups for the drug includes children and teenagers - basically, anyone below the age of 18 is at high risk of side effects. In addition to that are pregnant females must refrain from the usage of the drug unless prescribed by the doctor.

Perindopril Indications

Perindopril is indicated for the treatment of

  • High Blood Pressure
  • Congestive Heart Failure
  • Hypertensive Symptoms
  • Chronic Hypertension
  • Other Coronary and Heart Diseases and Conditions.

How Do I Buy Perindopril Online?

Perindopril can be ordered online in the UK with convenience from [this website] after filling out a prescription form. Do not take excessive dose of the medication and always use it according to your doctor’s prescription to prevent any bodily harm and severe side effects.

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Perindopril is a medicine produced in the form of tablets for the long term treatment of hypertension (high blood pressure). The drug is included in the class of angiotensin-converting enzyme (ACE) inhibitors.

Perindopril is also prescribed to reduce the risk of heart-related complications if one suffers from coronary artery disease. These complications include conditions like stroke or heart attack. Taking Perindopril also improves the chances of survival of a patient after heart surgery or a heart attack. The drugs work by relaxing and widening up blood vessels which result in reduced blood pressure.  It prevents the release of some natural chemicals which not only improve the blood flow making it smoother but also tighten the blood vessels.

Perindopril works by improving the blood flow by preventing the production of some natural chemicals - helping the blood vessel to relax and widen up. This result in reduced blood pressure which makes it easier for your heart to pump blood around your body.

Perindopril is referred to as a nonsulfhydryl prodrug that pertains to the angiotensin-converting enzyme (ACE) inhibitor class of medications. The drug effectively reduces the symptoms of hypertension as it rapidly metabolizes in the liver actively. 

Perindoprilat is a strong, aggressive inhibitor of ACE, which is the enzyme that converts angiotensin I (ATI) to angiotensin II (ATII). ATII maintain the blood pressure and is a significant part of the renin-angiotensin-aldosterone system (RAAS).

Perindopril is effective to treat medium to moderate level complications through hypertension, reducing the risk of congestive heart failure, and to limit and minimise the cardiovascular risk of patients with high blood or post-myocardial infarction and stable coronary disease.

Intake of Perindopril decreases morbidity and mortality by minimizing the risk of the onset of stroke, renal failure, and diabetes.

Perindopril is also prescribed to the patients suffering from more advanced versions of the cardiovascular continuum as it helps to improve long-term prognosis in coronary artery disease.

Perindopril also helps to reduces cardiac remodeling following myocardial infarction and improves patient symptoms and prognosis in diastolic heart failure. Current trial evidence confirms the clinical benefits of perindopril throughout the cardiovascular continuum, thus slowing the progression of cardiovascular disease and improving patient prognosis.

  • Control Blood Pressure
  • Reduce Cardiac remodeling following myocardial infarction
  • Improves symptoms and prognosis in diastolic heart failure
  • Helps the Blood Vessels Relax and widen up
  • Widens the Arteries and Veins
  • Improves the blood flow of the body

Perindopril comes as an oral tablet usually prescribed for long-term treatment. When prescribed by the doctor it is better to complete the course as discontinuing in the middle of the course may lead to high blood pressure that can further result in a sudden stroke or cardiac arrest. Only use this medication in compliance with doctor’s prescription and do not alter your dosage on the basis of personal observations. If you feel you need to change the dosage, consult your doctor first.

The drug may not work as effectively as it should if the drugs are not taken on the suggested schedule by the doctor. In case of overdose, the drug may cause various side effects including imbalances in blood pressure, and high potassium levels. Perindopril can be taken with or without food and the tablet can be cut into half if needed.

Adults who are 18–64 years are usually prescribed to take 4 mg taken once per day. The quantity can vary as per the severity of the condition and symptoms. A typical dosage may lie between 4–8 mg taken once per day or split into two divided doses. This drug hasn’t been studied in children. It shouldn’t be used in people younger than 18 years.

Side Effects

Side Effects of the medication can be mild to strong varying as per the quantity of overdose. Symptoms that may arise in severe cases include dizziness, weakness, headaches, upset stomach, stomach pain, diarrhoea, cough, back pain.

Warnings

It should be used with caution by patients with a medical history of angioedema, high blood levels of potassium, kidney disease or dialysis, salt restrictive diet, liver disease or any related allergy.

High-Risk Groups

High-risk groups for the drug includes children and teenagers - basically, anyone below the age of 18 is at high risk of side effects. In addition to that are pregnant females must refrain from the usage of the drug unless prescribed by the doctor.

Perindopril is indicated for the treatment of

  • High Blood Pressure
  • Congestive Heart Failure
  • Hypertensive Symptoms
  • Chronic Hypertension
  • Other Coronary and Heart Diseases and Conditions.

Perindopril can be ordered online in the UK with convenience from [this website] after filling out a prescription form. Do not take excessive dose of the medication and always use it according to your doctor’s prescription to prevent any bodily harm and severe side effects.

Frequently Asked Questions

Perindopril and Indapamide lower blood pressure more effectively when taken together. Dose adjustments are necessary for safe use, so it is important to use this combination as prescribed. If you experience any side effects such as dizziness, fainting, or headaches, then it is important that you contact your healthcare professional immediately.

No, Perindopril cannot be used as a blood-thinning agent, as it doesn’t have anticoagulant properties to prevent the formation of blood clots. If you are taking heparin while using Perindopril, then there is a possibility of drug interactions, which can increase the risk of high potassium levels in your blood. Speak with your healthcare provider to have a full understanding of the interaction of other medications with Perindopril.

In adults, the usual recommended starting dosage is 4 mg, which must be taken orally once daily. After two to three weeks, an 8 mg dose may be prescribed depending on the improvement in the condition. The maximum dose of Perindopril is 16 mg.

If you are taking Perindopril, then you must avoid foods that are rich in potassium, any salt substitutes containing potassium, and potassium supplements. This is because a high intake of potassium can result in hyperkalaemia (high potassium levels in the blood). Also, limit or avoid alcohol intake as it can increase the lowering effect of blood pressure caused by Perindopril.

Your first dose of Perindopril should usually be taken at night, as it can cause dizziness. Once you no longer feel dizzy, you can begin taking the medication in the morning. You must take the Perindopril tablet on an empty stomach, i.e. at least 30 to 60 minutes before breakfast.

Perindopril usually starts working within a few hours and may take up to four weeks to experience its maximum benefit. It can stay in your system for up to 17 hours, so taking it daily ensures a continuous effect. Hence, it is necessary to take the medicine regularly and not to stop the medication without the advice of your healthcare professional, as doing so may cause symptoms to return.

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Review By

HARMINDER ‘HARMY’ KAUR

Last Updated On : Mar 13 2026

BSc(hons) Pharmacy

GPhC Number: 2061107

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Authored By

GURDEV SEHMI

Last Reviewed On : Mar 23 2026

BSc Pharm, MRPharmS, Independent Prescriber, Superintendent Pharmacist, Clinical Lead

GPhC Number: 2050925