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What are Perindopril Tablets?
Perindopril is a medicine produced in the form of tablets for the long term treatment of hypertension (high blood pressure). The drug is included in the class of angiotensin-converting enzyme (ACE) inhibitors.
Perindopril is also prescribed to reduce the risk of heart-related complications if one suffers from coronary artery disease. These complications include conditions like stroke or heart attack. Taking Perindopril also improves the chances of survival of a patient after heart surgery or a heart attack. The drugs work by relaxing and widening up blood vessels which result in reduced blood pressure. It prevents the release of some natural chemicals which not only improve the blood flow making it smoother but also tighten the blood vessels.
How Does Perindopril Work?
Perindopril works by improving the blood flow by preventing the production of some natural chemicals - helping the blood vessel to relax and widen up. This result in reduced blood pressure which makes it easier for your heart to pump blood around your body.
Perindopril is referred to as a nonsulfhydryl prodrug that pertains to the angiotensin-converting enzyme (ACE) inhibitor class of medications. The drug effectively reduces the symptoms of hypertension as it rapidly metabolizes in the liver actively.
Perindoprilat is a strong, aggressive inhibitor of ACE, which is the enzyme that converts angiotensin I (ATI) to angiotensin II (ATII). ATII maintain the blood pressure and is a significant part of the renin-angiotensin-aldosterone system (RAAS).
Perindopril is effective to treat medium to moderate level complications through hypertension, reducing the risk of congestive heart failure, and to limit and minimise the cardiovascular risk of patients with high blood or post-myocardial infarction and stable coronary disease.
What Are the Benefits of Taking Perindopril?
Intake of Perindopril decreases morbidity and mortality by minimizing the risk of the onset of stroke, renal failure, and diabetes.
Perindopril is also prescribed to the patients suffering from more advanced versions of the cardiovascular continuum as it helps to improve long-term prognosis in coronary artery disease.
Perindopril also helps to reduces cardiac remodeling following myocardial infarction and improves patient symptoms and prognosis in diastolic heart failure. Current trial evidence confirms the clinical benefits of perindopril throughout the cardiovascular continuum, thus slowing the progression of cardiovascular disease and improving patient prognosis.
- Control Blood Pressure
- Reduce Cardiac remodeling following myocardial infarction
- Improves symptoms and prognosis in diastolic heart failure
- Helps the Blood Vessels Relax and widen up
- Widens the Arteries and Veins
- Improves the blood flow of the body
How Do I Use Perindopril?
Perindopril comes as an oral tablet usually prescribed for long-term treatment. When prescribed by the doctor it is better to complete the course as discontinuing in the middle of the course may lead to high blood pressure that can further result in a sudden stroke or cardiac arrest. Only use this medication in compliance with doctor’s prescription and do not alter your dosage on the basis of personal observations. If you feel you need to change the dosage, consult your doctor first.
The drug may not work as effectively as it should if the drugs are not taken on the suggested schedule by the doctor. In case of overdose, the drug may cause various side effects including imbalances in blood pressure, and high potassium levels. Perindopril can be taken with or without food and the tablet can be cut into half if needed.
Perindopril Dosage
Adults who are 18–64 years are usually prescribed to take 4 mg taken once per day. The quantity can vary as per the severity of the condition and symptoms. A typical dosage may lie between 4–8 mg taken once per day or split into two divided doses.
This drug hasn’t been studied in children. It shouldn’t be used in people younger than 18 years.
Perindopril Precautions and Side Effects
Side Effects
Side Effects of the medication can be mild to strong varying as per the quantity of overdose. Symptoms that may arise in severe cases include dizziness, weakness, headaches, upset stomach, stomach pain, diarrhoea, cough, back pain.
Warnings
It should be used with caution by patients with a medical history of angioedema, high blood levels of potassium, kidney disease or dialysis, salt restrictive diet, liver disease or any related allergy.
High-Risk Groups
High-risk groups for the drug includes children and teenagers - basically, anyone below the age of 18 is at high risk of side effects. In addition to that are pregnant females must refrain from the usage of the drug unless prescribed by the doctor.
Perindopril Indications
Perindopril is indicated for the treatment of
- High Blood Pressure
- Congestive Heart Failure
- Hypertensive Symptoms
- Chronic Hypertension
- Other Coronary and Heart Diseases and Conditions.
How Do I Buy Perindopril Online?
Perindopril can be ordered online in the UK with convenience from [this website] after filling out a prescription form. Do not take excessive dose of the medication and always use it according to your doctor’s prescription to prevent any bodily harm and severe side effects.
