Duac gel contains two active ingredients: clindamycin and benzoyl peroxide. Duac gel belongs to the group of medicines known as ...
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About Duac Gel

Duac is a medication that is used to treat mild or moderate acne, spots, and pimples. These conditions appear on your skin because of an overproduction of a chemical called sebum, clogging pores and allowing oil to build up, creating blackheads. If these blackheads become infected with bacteria they will develop into acne. This will usually present itself on the face; however it can appear on other parts of the body, particularly the neck and upper back. Duac Gel targets these pimples directly and aids in the prevention of new impurities.

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What is Duac Once Daily Gel?

The Duac gel Superdrug contains two active ingredients: clindamycin and benzoyl peroxide. Duac gel belongs to the group of medicines known as anti-acne preparations.

Duac gel is indicated for the treatment of mild to moderate acne vulgaris.

  • Clindamycin is an antibiotic that prevents the bacteria involved in acne from reproducing.
  • Benzoyl peroxide works by reducing comedones (blackheads and whiteheads) and it also kills the bacteria involved in acne.

When these active ingredients are used together in Duac gel, they help to:

  • fight acne-causing bacteria
  • treat blackheads, whiteheads, and pimples
  • reduce the number of red and inflamed acne pimples.

Duac gel is indicated in adults and adolescents 12 years and older

How does it work?

The active ingredient in this acne medication is Clindamycin, a lincosamide antibiotic with bacteriostatic action against Gram-positive aerobes and a wide range of anaerobic bacteria. Lincosamides, such as clindamycin, binds to the 23S subunit of the bacterial ribosome and inhibit the early stages of protein synthesis. The action of clindamycin is predominantly bacteriostatic, although high concentrations may be slightly bactericidal against sensitive strains.

Although clindamycin phosphate is inactive in vitro, rapid hydrolysis in vivo converts this component into active antibacterial clindamycin. Clindamycin activity has been clinically demonstrated in comedones of acne patients at levels sufficient to be active against most strains of Propionibacterium acnes. Clindamycin in-vitro inhibits all Propionibacterium acnes cultures tested (MIC 0.4 mcg / ml). Free fatty acids on the skin surface decreased from approximately 14% to 2% after the application of clindamycin.

Benzoyl peroxide is a mild keratolytic that works against comedones at all stages of its development. It is an oxidizing agent with bactericidal activity against Propionibacterium acnes, the organism involved in acne vulgaris. In addition, it is sebostatic, counteracting the excessive production of sebum associated with acne.

Duac gel has a combination of moderate and antibacterial keratolytic properties, which is particularly active against mild to moderate inflammatory acne vulgaris lesions.

The prevalence of acquired resistance can vary geographically and overtime in the selected species. It is useful to know the local information on resistance, particularly when treating serious infections.

The inclusion of benzoyl peroxide reduces the potential for the emergence of clindamycin resistant organisms.

The presentation of both active ingredients in a product is more appropriate and ensures compliance with the treatment by the patient.

What are the benefits of taking it?

This Rosacea treatment medication is prescribed to treat mild and moderate cases of acne (also known as pimples). Pimples appear when the sebaceous glands produce too much sebum, leaving the skin oily. When sebum clogs the pores, comedones form. If the acne-causing bacteria infects comedones, they become inflamed and turn into pimples. Acne appears mostly on the face, but can also affect the neck and shoulders. Duac Acne Acne Gel reduces pimples and comedones and prevents the appearance of new impurities.

How do I use it and its dosage?

Always use this medicine exactly as your doctor or pharmacist has told you. If in doubt, consult your doctor or pharmacist again.

  • Use Duac gel once a day in the evening.
  • It can take between 2 and 5 weeks before observing the effect of Duac gel.
  • Do not use Duac gel for more than 12 weeks in a row. Your doctor will indicate the duration of treatment.

How to apply Duac gel

  1. Remove any makeup remnants.
  2. Wash the affected skin area well. Rinse with lukewarm water and pat dry gently.
  3. Apply a thin layer of gel to the entire affected skin area using your fingertips.
  4. Apply the product on all acne-prone skin areas, not just on the pimples. If the gel is not easily absorbed, you are using too much product.
  5. For the face, use the amount of gel that comes out of the tube and reaches from the tip of the finger to the first joint (the first crease of the finger). That is, the fingertip.
  6. For the face and back, use two and a half fingertips in total.
  7. If you have very dry skin, or your skin is peeling, use an oil-free cream, use Duac gel less often, or stop applying the treatment for a short period of time to allow the skin to heal. adapt to treatment. This medication may not work properly if it is not applied every day.
  8. Wash your hands after applying the gel.
  9. Once the product has dried, you can use non-greasy makeup if you wish.

Side effects & precautions

Like all medicines, this duo acne cream can cause side effects, although not everybody gets them.

If you notice any of the serious side effects listed below, stop using Duac gel and contact your doctor immediately, could you need urgent medical attention:

  • signs of an allergic reaction (such as swelling of the face, eyes, lips, or tongue, hives, difficulty breathing, collapse)
  • prolonged or severe diarrhea, or abdominal cramps
  • severe stinging, peeling, or itching.

If you notice any Duac once-daily gel side effects, try using the gel less often, or stop using it for a day or two and then start the treatment again.

Very common side effects (affect at least 1 in 10 people)

  • Redness, peeling, dryness.
  • These side effects are generally mild.

Frequent side effects (affect less than 1 in 10 people)


At the application site:

  • Stinging, pain, sensitivity to sunlight.

Uncommon side effects (affect less than 1 in 100 people)

  • Tickling (paresthesia), worsening acne, redness, itchy skin, rash (dermatitis, erythematous rash).

Other adverse effects

A small number of people have had other side effects, but the exact frequency of these is unknown:

Allergic reactions.

  • Inflammation of the intestine, diarrhea, including bloody diarrhea, stomach pain.

At the application site:

  • Skin reactions, skin discoloration.
  • Itchy, inflammatory rash (hives).

Buying Duac Once Daily Gel online.

You can buy Duac Once Daily Gel online through one of the UK’s leading online pharmacies, Pharmacy Planet. It's easy and convenient. You will need to fill out a short assessment and the item will be delivered directly to your door. If you want to buy this antibacterial gel online, use Pharmacy Planet, a UK pharmacy you can trust.
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