Facebook Pixel
New Patients – Get 10% Off Your First Consultation with Code: NEW10 at Checkout
Epiduo is indicated for the treatment of acne. Epiduo gel contains two active ingredients, adapalene, and benzoyl peroxide, which work together but in different ways. Adapalene belongs to a group of substances known as retinoids and specifically acts on the skin processes that cause acne. The other active ingredient, benzoyl peroxide, acts as an antibacterial and exerts a calming and exfoliating action on the outermost layer of the skin. Apply a thin layer of gel evenly to acne-affected areas once daily before bed, avoiding eyes, lips, and nostrils. The skin must be clean and dry before application. You should wash your hands carefully after using Epiduo.
Consult
Select
Checkout
01
Select

the items you wish
to order

02
Order reviewed

by our qualified
prescriber

03
Delivered

to your door step

Your Selection

Please use the options provided to make your final selection.

prodName
Epiduo Gel
£32
Total
Consult
Select
Checkout
Please make a selection

Please note that whilst you are able to request the medicine strength and size required,
we will only be able to send on approval from our in house pharmacist.

Starts at £32.00
Price Comparison

Select your preferred options and see the best price

PackPrice (£)
--45g x 132.00
--45g x 260.00

It looks like you missed filling in questions from the last consultation.Click Here to submit your response.

  • No hidden fees

  • Secure checkout

  • UK Regulated online pharmacy

  • Trusted by over 100,000+ customers

Epiduo 0.1 / 2.5 % 45g Gel for Acne Treatment

Epiduo Gel is widely trusted for soothing breakouts and reveal clearer, smoother-looking skin. It combines adapalene and benzoyl peroxide, making it a powerful acne treatment that targets blocked pores, inflammation, and acne bacteria all at once. Many people choose to buy Epiduo gel when they want an effective pimple treatment that fits easily into their daily skincare routine.

As it treats both comedonal acne and inflamed breakouts, Epiduo gel is often recommended for people who experience blackheads, whiteheads, persistent pimples, or repeated congestion. If you want to purchase an acne medication that works on multiple causes of breakouts, Epiduo gel is a reliable and clinically proven option to consider.

What Is Epiduo Gel?

Epiduo gel is a topical acne treatment that contains two active ingredients, which are adapalene 0.1%, a retinoid that supports skin renewal, and benzoyl peroxide 2.5%, an antibacterial ingredient that keeps pores clear. Together, they prevent new spots, reduce inflammation, and improve overall skin texture.

Epiduo gel is suitable for mild to moderate acne and is often chosen when over-the-counter acne creams are not strong enough. As it targets both pore blockage and acne bacteria, it can be used as a long-term solution for managing breakouts and improving skin clarity.

Epiduo gel is an acne gel that is said to deliver steady and noticeable results with consistent use. If you struggle with recurring breakouts or comedonal acne, Epiduo gel may be a helpful addition to your routine.

How Does Epiduo Gel Work?

Epiduo gel works through a two-way approach to acne treatment:

1. Adapalene Supports Skin Renewal

This ingredient regulates skin cell turnover, preventing dead skin from clogging the pores. Over time, this reduces the formation of blackheads and whiteheads.

2. Benzoyl Peroxide Targets Acne Bacteria

This ingredient reduces the number of acne-causing bacteria on the skin and calms inflamed spots. It also keeps pores free from excess oil and prevents bacterial resistance.

Together, adapalene and benzoyl peroxide create a complete acne solution that treats both the visible spots and the underlying causes. Many people begin to notice smoother skin within a few weeks, although the full benefits continue to develop over several months.

Mild irritation is normal during the early stages as the skin adjusts.

How to Use Epiduo Gel?

To use Epiduo gel correctly, apply a thin, even layer of the gel to clean, dry skin once daily, usually at night. A pea-sized amount is usually enough for the entire face.

Helpful Tips for the Best Results:

  • Begin slowly if you have sensitive skin.
  • Moisturise daily to reduce dryness.
  • Avoid strong exfoliants and harsh scrubs.
  • Always apply sunscreen in the morning.
  • Do not use other retinoids at the same time.

Most people begin noticing improvements after 4 to 8 weeks, with clearer results appearing as treatment continues. Epiduo gel works best as part of a simple and consistent skincare routine.

Who Can Use Epiduo Gel?

Epiduo gel may be suitable for adults and teenagers with:

  • Mild to moderate acne.
  • Blackheads and whiteheads.
  • Red, inflamed spots.
  • Comedonal acne.
  • Oily or congested skin.

Epiduo gel may not be suitable for individuals who:

  • Have very sensitive or eczema-prone skin.
  • Have a known allergy to retinoids or benzoyl peroxide.
  • Are using other topical acne medication.
  • Are pregnant or trying to conceive.

Do not use Epiduo gel if you are pregnant, planning pregnancy, or breastfeeding, unless specifically advised by a clinician.

If you are unsure whether Epiduo gel is right for you, you can complete a quick online consultation with Pharmacy Planet. A prescriber will check your suitability before you order.

Possible Side Effects of Epiduo Gel

Epiduo gel is well tolerated by most people, but some may experience:

Common Side Effects:

  • Dryness
  • Redness
  • Mild stinging
  • Flaking or peeling

These effects are common in the early stages and usually improve as the skin adjusts. Moisturising regularly and using a gentle cleanser can make the process more comfortable.

If irritation becomes persistent, reduce the frequency of application and speak to a prescriber for advice.

Why Do People Choose to Buy Epiduo Gel?

Epiduo gel is a popular choice because it:

  • Combines two effective acne ingredients.
  • Helps prevent clogged pores.
  • Reduces inflamed spots.
  • Supports long-term acne control.
  • Improves skin texture.
  • Works for both teenage and adult acne.
  • Fits easily into a simple skincare routine.

If you want to purchase an anti-acne gel that targets multiple causes of breakouts, Epiduo gel is clinically proven to be effective for mild to moderate acne.

Consultation and Prescription Process at Pharmacy Planet

Here is how the order and approval process works at Pharmacy Planet:

  1. Complete the quick online consultation.
  2. A UK prescriber reviews your answers.
  3. If suitable, your prescription is approved.
  4. Your treatment is delivered discreetly to your door.
Epiduo 0.1 / 2.5 % 45g Gel

Epiduo Gel is widely trusted for soothing breakouts and reveal clearer, smoother-looking skin. It combines adapalene and benzoyl peroxide, making it a powerful acne treatment that targets blocked pores, inflammation, and acne bacteria all at once. Many people choose to buy Epiduo gel when they want an effective pimple treatment that fits easily into their daily skincare routine.

As it treats both comedonal acne and inflamed breakouts, Epiduo gel is often recommended for people who experience blackheads, whiteheads, persistent pimples, or repeated congestion. If you want to purchase an acne medication that works on multiple causes of breakouts, Epiduo gel is a reliable and clinically proven option to consider.

Epiduo gel is a topical acne treatment that contains two active ingredients, which are adapalene 0.1%, a retinoid that supports skin renewal, and benzoyl peroxide 2.5%, an antibacterial ingredient that keeps pores clear. Together, they prevent new spots, reduce inflammation, and improve overall skin texture.

Epiduo gel is suitable for mild to moderate acne and is often chosen when over-the-counter acne creams are not strong enough. As it targets both pore blockage and acne bacteria, it can be used as a long-term solution for managing breakouts and improving skin clarity.

Epiduo gel is an acne gel that is said to deliver steady and noticeable results with consistent use. If you struggle with recurring breakouts or comedonal acne, Epiduo gel may be a helpful addition to your routine.

Epiduo gel works through a two-way approach to acne treatment:

1. Adapalene Supports Skin Renewal

This ingredient regulates skin cell turnover, preventing dead skin from clogging the pores. Over time, this reduces the formation of blackheads and whiteheads.

2. Benzoyl Peroxide Targets Acne Bacteria

This ingredient reduces the number of acne-causing bacteria on the skin and calms inflamed spots. It also keeps pores free from excess oil and prevents bacterial resistance.

Together, adapalene and benzoyl peroxide create a complete acne solution that treats both the visible spots and the underlying causes. Many people begin to notice smoother skin within a few weeks, although the full benefits continue to develop over several months.

Mild irritation is normal during the early stages as the skin adjusts.

To use Epiduo gel correctly, apply a thin, even layer of the gel to clean, dry skin once daily, usually at night. A pea-sized amount is usually enough for the entire face.

Helpful Tips for the Best Results:

  • Begin slowly if you have sensitive skin.
  • Moisturise daily to reduce dryness.
  • Avoid strong exfoliants and harsh scrubs.
  • Always apply sunscreen in the morning.
  • Do not use other retinoids at the same time.

Most people begin noticing improvements after 4 to 8 weeks, with clearer results appearing as treatment continues. Epiduo gel works best as part of a simple and consistent skincare routine.

Epiduo gel may be suitable for adults and teenagers with:

  • Mild to moderate acne.
  • Blackheads and whiteheads.
  • Red, inflamed spots.
  • Comedonal acne.
  • Oily or congested skin.

Epiduo gel may not be suitable for individuals who:

  • Have very sensitive or eczema-prone skin.
  • Have a known allergy to retinoids or benzoyl peroxide.
  • Are using other topical acne medication.
  • Are pregnant or trying to conceive.

Do not use Epiduo gel if you are pregnant, planning pregnancy, or breastfeeding, unless specifically advised by a clinician.

If you are unsure whether Epiduo gel is right for you, you can complete a quick online consultation with Pharmacy Planet. A prescriber will check your suitability before you order.

Epiduo gel is well tolerated by most people, but some may experience:

Common Side Effects:

  • Dryness
  • Redness
  • Mild stinging
  • Flaking or peeling

These effects are common in the early stages and usually improve as the skin adjusts. Moisturising regularly and using a gentle cleanser can make the process more comfortable.

If irritation becomes persistent, reduce the frequency of application and speak to a prescriber for advice.

Epiduo gel is a popular choice because it:

  • Combines two effective acne ingredients.
  • Helps prevent clogged pores.
  • Reduces inflamed spots.
  • Supports long-term acne control.
  • Improves skin texture.
  • Works for both teenage and adult acne.
  • Fits easily into a simple skincare routine.

If you want to purchase an anti-acne gel that targets multiple causes of breakouts, Epiduo gel is clinically proven to be effective for mild to moderate acne.

Here is how the order and approval process works at Pharmacy Planet:

  1. Complete the quick online consultation.
  2. A UK prescriber reviews your answers.
  3. If suitable, your prescription is approved.
  4. Your treatment is delivered discreetly to your door.
Frequently Asked Questions

Most people start noticing improvements after 4 to 8 weeks. Full results continue to build with ongoing use.

Yes, moisturiser is highly recommended as it reduces dryness and irritation.

Yes, you can apply makeup once the gel has absorbed. Choose non-comedogenic products.

Avoid exfoliating acids, scrubs, or other retinoids unless advised. These can irritate the skin.

Epiduo gel is designed for acne treatment, not rosacea care. If you have rosacea-like symptoms, seek a different treatment recommendation.

Yes, as long as the skin is clean and unbroken, Epiduo gel can be used on other acne-prone areas.

Reduce application frequency and use a gentle moisturiser. The skin usually adapts with time.

How it works
Start Consultation
Complete our online
clinical consultation

Answer a few questions on your health and your fitness goals.

Setup Coaching
Clinical
assessment

Our clinicians will review your clinical questionnaire to make sure treatment is right for you.

Ongoing Support
Welcome
aboard!

Once approved, you will access our wealth of experience and resources curated by our team and begin your clinical journey.

Start your journey with us

What our patients are saying

Need Help?

question mark
Do you have a question about weight loss treatment?

Start your weight loss journey heading in the right direction. Our team are here to help. Whether you’re unsure about which medicine is right for you or need help navigating the world of weight loss drugs, our team are on hand to help you make the right decision. We can put you in touch with one of our experienced weight loss clinicians so you can be sure you’re making the best decision with the most accurate information.

To get in touch, contact our Customer Service team on 0800 978 8956 or email [email protected].

Meet the team
Pharmacist Image

Authored on : January 6 2026

HARMINDER ‘HARMY’ KAUR

BSc(hons) Pharmacy

GPhC Number: 2061107

Pharmacist Image

Reviewed on : January 6 2026

GURDEV SEHMI

BSc Pharm, MRPharmS, Independent Prescriber, Superintendent Pharmacist, Clinical Lead

2050925