Ovestin Cream
Ovestin belongs to a group of medications called hormone replacement therapy (HRT). Contains the female hormone estriol (estrogen). Ovestin is used in postmenopausal women who have had their last menstrual period naturally for at least 12 months. It is used to relieve menopausal symptoms in the vagina, such as dryness or irritation. In medical terms, this is known as "vaginal atrophy." This is caused by a drop in estrogen levels in your body. This happens naturally after menopause. If the ovaries are surgically removed (ovariectomy) before menopause, the decrease in estrogen production occurs very abruptly. Estrogen deficiency during menopause can cause the vaginal wall to become thin and dry (vaginal dryness). Therefore, sexual intercourse can be painful and vaginal irritation and infections can occur. Estrogen deficiency can also lead to symptoms like urinary incontinence and recurrent cystitis. Ovestin works by replacing the estrogen that is normally produced in the ovaries. It is inserted into your vagina, so the hormone is released where it is needed. This can alleviate vaginal discomfort.
the items you wish
to order
by our qualified
prescriber
to your door step
Please use the options provided to make your final selection.

Select your preferred options and see the best price
| Pack | Price (£) | ||
|---|---|---|---|
| - | - | 15g x 1 Tube | 26.00 |
| - | - | 15g x 2 Tubes | 41.00 |
It looks like you missed filling in questions from the last consultation.Click Here to submit your response.
What is Ovestin?
Ovestin is a hormonal preparation that contains the active ingredient estradiol, a natural form of the main female sex hormone, estrogen. Ovestin alleviates menopausal symptoms in menopausal or postmenopausal women by bringing hormone levels back to normal. This is what is known as hormone replacement therapy (HRT). Ovestin is only sold by prescription.
How does it work?
Ovestin 1mg contains the natural female hormone estriol. Unlike other estrogens, estriol is a short-acting estrogen. It replaces the lack of estrogenic production. In the case of vaginal atrophy, vaginally applied estriol induces normalization of the urogenital epithelium and helps restore normal microflora and the physiological pH of the vagina. Treatment of Vaginal Estrogen Deficiency Symptoms: Vaginally applied estrogen relieves symptoms of vaginal atrophy due to estrogen deficiency in postmenopausal women.
What are the benefits of taking it?
Ovestin estriol 1mg vaginal cream is used to relieve vaginal menopausal symptoms such as vaginal dryness, irritation or itching, pain during sexual intercourse, and increased sensitivity to vaginal or urinary tract infections. Loss of estrogen in the body due to menopause can lead to thinning of the vaginal walls, which in turn can lead to discomfort. The active ingredient estriol improves the condition of the vaginal tissues, providing short-term relief from these uncomfortable symptoms.
How do I use it and its dosage?
Always use this medicine exactly as your doctor or pharmacist has told you. If in doubt, consult your doctor or pharmacist again.
Never exceed the dose prescribed by your doctor.
The recommended dose for vaginal discomfort is a daily application during the first weeks (maximum 4 weeks) and then the dose is gradually decreased until, for example, an application twice a week.
To improve wound healing in postmenopausal women undergoing vaginal surgery, the usual dose is 1 daily application for 2 weeks before surgery and then 1 application twice a week for 2 weeks after surgery.
To help evaluate vaginal smears from postmenopausal women, the usual dose is 1 application daily each day of the week before the test.
Your doctor may interrupt the treatment every 2-3 months for a period of 4 weeks to assess whether it is necessary to continue.
Instructions for the correct administration of the preparation
Use the applicator to apply the cream to the vagina. It is advisable to do it before bed.
One application (applicator filled to the mark) contains 1g of Ovestin cream, which in turn contains 1mg of estriol.
- Uncap the tube, invert the cap, and use the sharp tip to open the tube seal.
- Screw the applicator onto the tube. Make sure the plunger is fully inserted into the cylinder.
- Slowly squeeze the tube so that enough cream penetrates the applicator to fill it up to the mark.
- Unscrew the applicator and recap the tube.
- To apply the cream, lie down and insert the end of the applicator deep into the vagina
- Slowly push in the plunger until the applicator is empty.
- After use, pull the plunger out of the cylinder past the resistance point and wash it together with the applicator in warm soapy water, rinsing well afterward. Do not use detergents. Rinse well afterward.
- The applicator can be re-engaged by fully inserting the plunger into the cylinder past the point of resistance.
Discard the applicator once the tube is empty.
The maximum dose (1 application per day) should not be used for more than 2-3 weeks.
Your doctor will try to prescribe the lowest dose to treat your symptoms for the shortest time necessary. If you feel that the effect of Ovestin is too strong or too weak, tell your doctor.
If you use more Ovestin than you should
In case of overdose or accidental ingestion, immediately consult your doctor or pharmacist or call the Toxicology Information Service, telephone 91 562 04 20, indicating the medicine and the amount ingested.
If someone ingests some cream they should consult a doctor. Symptoms that may appear are nausea and vomiting; Vaginal bleeding may also occur in women and girls after a few days.
Side effects & precautions
Like all medicines, this urogenital atrophy natural remedy can cause side effects, although not everybody gets them.
Compared to women not using hormone replacement therapy, the following diseases have been reported more frequently in women using hormone replacement therapy circulating in the blood.
These risks affect less vaginally administered treatments like Ovestin:
- breast cancer
- ovarian cancer
- blood clots in the veins of the legs or lungs (venous thromboembolism)
- stroke
- probable memory loss if hormone replacement therapy is started after age 65.
Depending on the dose and sensitivity of the patient, Ovestin may infrequently cause side effects such as:
- swelling and increased tenderness in the breasts.
- slight vaginal bleeding
- increased vaginal discharge
- sickness
- fluid retention in tissues, usually marked by swollen ankles or feet
- local irritation or itching
The following side effects associated with other hormone replacement therapies have been reported.
- gallbladder diseases
- various skin disorders
- pigmentation of the skin, especially of the face or neck, known as "pregnancy spots" (chloasma)
- painful and reddish nodules on the skin (erythema nodosum)
- skin rash with target-shaped lesions or reddish papules (erythema multiforme).
Buying Ovestin online
You can buy Ovestin online through one of the UK’s leading online pharmacies, Pharmacy Planet. It's easy and convenient. You will need to fill out a short assessment and the item will be delivered directly to your door. If you want to buy this vulvar atrophy and atrophic urethritis treatment medication online, use Pharmacy Planet, a UK pharmacy you can trust.
Ovestin cream vs Ovestin tablets
If you are using Ovestin for vaginal dryness, then it is better to use Ovestin cream rather than tablets, as it helps to lower the plasma levels of oestrogen. It also seems to be more effective in controlling site-specific symptoms.
Who cannot use Ovestin cream?
You should not use Ovestin cream if you are planning a pregnancy, are pregnant, or are breastfeeding. Also, avoid using it if you have:
- An allergy to any of the ingredients present in the medication
- Porphyria
- Liver problems
- A history of heart attack, chest pain, or angina
- Current or past breast or sex organ cancer
- Vaginal bleeding
Ovestin is a hormonal preparation that contains the active ingredient estradiol, a natural form of the main female sex hormone, estrogen. Ovestin alleviates menopausal symptoms in menopausal or postmenopausal women by bringing hormone levels back to normal. This is what is known as hormone replacement therapy (HRT). Ovestin is only sold by prescription.
Ovestin 1mg contains the natural female hormone estriol. Unlike other estrogens, estriol is a short-acting estrogen. It replaces the lack of estrogenic production. In the case of vaginal atrophy, vaginally applied estriol induces normalization of the urogenital epithelium and helps restore normal microflora and the physiological pH of the vagina. Treatment of Vaginal Estrogen Deficiency Symptoms: Vaginally applied estrogen relieves symptoms of vaginal atrophy due to estrogen deficiency in postmenopausal women.
Ovestin estriol 1mg vaginal cream is used to relieve vaginal menopausal symptoms such as vaginal dryness, irritation or itching, pain during sexual intercourse, and increased sensitivity to vaginal or urinary tract infections. Loss of estrogen in the body due to menopause can lead to thinning of the vaginal walls, which in turn can lead to discomfort. The active ingredient estriol improves the condition of the vaginal tissues, providing short-term relief from these uncomfortable symptoms.
Always use this medicine exactly as your doctor or pharmacist has told you. If in doubt, consult your doctor or pharmacist again.
Never exceed the dose prescribed by your doctor.
The recommended dose for vaginal discomfort is a daily application during the first weeks (maximum 4 weeks) and then the dose is gradually decreased until, for example, an application twice a week.
To improve wound healing in postmenopausal women undergoing vaginal surgery, the usual dose is 1 daily application for 2 weeks before surgery and then 1 application twice a week for 2 weeks after surgery.
To help evaluate vaginal smears from postmenopausal women, the usual dose is 1 application daily each day of the week before the test.
Your doctor may interrupt the treatment every 2-3 months for a period of 4 weeks to assess whether it is necessary to continue.
Instructions for the correct administration of the preparation
Use the applicator to apply the cream to the vagina. It is advisable to do it before bed.
One application (applicator filled to the mark) contains 1g of Ovestin cream, which in turn contains 1mg of estriol.
- Uncap the tube, invert the cap, and use the sharp tip to open the tube seal.
- Screw the applicator onto the tube. Make sure the plunger is fully inserted into the cylinder.
- Slowly squeeze the tube so that enough cream penetrates the applicator to fill it up to the mark.
- Unscrew the applicator and recap the tube.
- To apply the cream, lie down and insert the end of the applicator deep into the vagina
- Slowly push in the plunger until the applicator is empty.
- After use, pull the plunger out of the cylinder past the resistance point and wash it together with the applicator in warm soapy water, rinsing well afterward. Do not use detergents. Rinse well afterward.
- The applicator can be re-engaged by fully inserting the plunger into the cylinder past the point of resistance.
Discard the applicator once the tube is empty.
The maximum dose (1 application per day) should not be used for more than 2-3 weeks.
Your doctor will try to prescribe the lowest dose to treat your symptoms for the shortest time necessary. If you feel that the effect of Ovestin is too strong or too weak, tell your doctor.
If you use more Ovestin than you should
In case of overdose or accidental ingestion, immediately consult your doctor or pharmacist or call the Toxicology Information Service, telephone 91 562 04 20, indicating the medicine and the amount ingested.
If someone ingests some cream they should consult a doctor. Symptoms that may appear are nausea and vomiting; Vaginal bleeding may also occur in women and girls after a few days.
Like all medicines, this urogenital atrophy natural remedy can cause side effects, although not everybody gets them.
Compared to women not using hormone replacement therapy, the following diseases have been reported more frequently in women using hormone replacement therapy circulating in the blood.
These risks affect less vaginally administered treatments like Ovestin:
- breast cancer
- ovarian cancer
- blood clots in the veins of the legs or lungs (venous thromboembolism)
- stroke
- probable memory loss if hormone replacement therapy is started after age 65.
Depending on the dose and sensitivity of the patient, Ovestin may infrequently cause side effects such as:
- swelling and increased tenderness in the breasts.
- slight vaginal bleeding
- increased vaginal discharge
- sickness
- fluid retention in tissues, usually marked by swollen ankles or feet
- local irritation or itching
The following side effects associated with other hormone replacement therapies have been reported.
- gallbladder diseases
- various skin disorders
- pigmentation of the skin, especially of the face or neck, known as "pregnancy spots" (chloasma)
- painful and reddish nodules on the skin (erythema nodosum)
- skin rash with target-shaped lesions or reddish papules (erythema multiforme).
You can buy Ovestin online through one of the UK’s leading online pharmacies, Pharmacy Planet. It's easy and convenient. You will need to fill out a short assessment and the item will be delivered directly to your door. If you want to buy this vulvar atrophy and atrophic urethritis treatment medication online, use Pharmacy Planet, a UK pharmacy you can trust.
If you are using Ovestin for vaginal dryness, then it is better to use Ovestin cream rather than tablets, as it helps to lower the plasma levels of oestrogen. It also seems to be more effective in controlling site-specific symptoms.
You should not use Ovestin cream if you are planning a pregnancy, are pregnant, or are breastfeeding. Also, avoid using it if you have:
- An allergy to any of the ingredients present in the medication
- Porphyria
- Liver problems
- A history of heart attack, chest pain, or angina
- Current or past breast or sex organ cancer
- Vaginal bleeding
Ovestin has been rebranded as Estriol Cream, manufactured by Aspen. This cream is applied inside the vagina or around the genital area to treat symptoms associated with the perimenopausal or menopausal period.
Ovestin cream helps relieve bladder issues in women going through menopause. It treats urogenital atrophy, which can cause incontinence, urinary urgency, and recurrent urinary tract infections.
Most users are tolerant of Ovestin cream, and it has not been linked with the risk of breast cancer. Still, it is better to consult your healthcare provider if you have a family history of breast cancer.
If you require a prescription to purchase Ovestin cream, you can complete the online consultation form available on our website. Your order will be approved if the medication is deemed suitable for you.
Estriol can be found in some topical face creams, which may help promote collagen production and add moisture to the skin, thereby reducing signs of ageing, such as fine lines and wrinkles.
If you think Ovestin is not suitable for you, you can consider the following alternatives used for vaginal dryness and irritation:
- Vagifem (estradiol) pessaries
- Estring (estradiol) ring
- Imvaggis (estriol) pessaries
- Blissel (estriol) gel

clinical consultation
Answer a few questions on your health and your fitness goals.

assessment
Our clinicians will review your clinical questionnaire to make sure treatment is right for you.

aboard!
Once approved, you will access our wealth of experience and resources curated by our team and begin your clinical journey.
Start your journey with us
Need Help?

Start your weight loss journey heading in the right direction. Our team are here to help. Whether you’re unsure about which medicine is right for you or need help navigating the world of weight loss drugs, our team are on hand to help you make the right decision. We can put you in touch with one of our experienced weight loss clinicians so you can be sure you’re making the best decision with the most accurate information.
To get in touch, contact our Customer Service team on 0800 978 8956 or email [email protected].
References:

Authored By
HARMINDER ‘HARMY’ KAUR
BSc(hons) Pharmacy
GPhC Number: 2061107

Reviewed By
GURDEV SEHMI
BSc Pharm, MRPharmS, Independent Prescriber, Superintendent Pharmacist, Clinical Lead
GPhC Number: 2050925














