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Sofradex/Dexamethasone + Framycetin + Gramicidin

Sofradex eye and ear drops contain three active ingredients, dexamethasone, framycetin, and gramicidin. Dexamethasone belongs to a group of medicines known as corticosteroids that are used to reduce inflammation. Framycetin and gramicidin are antibiotics that are included in these drops to prevent infections with bacteria. Inflammation of the external part of the ear canal (otitis externa). Short-term treatment of eye inflammation is also required when a bacterial infection is prevented, for example, after eye surgery. Corticosteroids are hormones naturally produced by the adrenal glands that have many important functions, including controlling inflammatory responses. Dexamethasone is a synthetic corticosteroid that can be administered to the eyes or ears to decrease inflammation.

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Sofradex/Dexamethasone + Framycetin + Gramicidin
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Please note that whilst you are able to request the medicine strength and size required,
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Starts at £37.00
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Sofradex Ear/Eye Drops for Infection Treatment and Inflammation Relief

Eye and ear infections can quickly become painful, irritating, and difficult to ignore, especially when swelling and discharge are involved. In these situations, a treatment that tackles both the infection and the inflammation is often needed to bring proper relief.

Sofradex ear drops are commonly prescribed for this purpose, offering a combined approach that treats bacterial infection while calming irritation inside the ear canal.

What Are Sofradex Ear/Eye Drops Used For?

Sofradex is a prescription treatment used to manage infections and inflammation in the ear and sometimes the eye. It is commonly prescribed for ear infection treatment, especially outer ear infections (otitis externa), inflamed ear canals causing pain, itching, or swelling, conditions where bacterial infection and irritation occur together, and situations requiring both antibacterial ear drops and anti-inflammatory treatment. These otic drops are particularly useful when symptoms go beyond mild irritation.

How Sofradex Ear/Eye Drops Work

Sofradex works by combining antibiotics with a steroid to treat both infection and inflammation. It contains framycetin, an antibiotic that kills bacteria causing infection; gramicidin, which supports antibacterial action against a wider range of bacteria; and dexamethasone, a corticosteroid that reduces swelling, redness, and discomfort.

This combination makes Sofradex effective as both an ocular antibiotic (for eye use) and a steroid ear drop treatment for ear conditions.

How to Use Sofradex Ear/Eye Drops Safely

Sofradex should be used exactly as prescribed to ensure effective treatment.

For Ear Use: Wash your hands before use. Tilt your head to one side. Apply 2–3 drops into the affected ear. Keep your head tilted for a few minutes.

For Eye Use: Wash your hands before use. Tilt your head back and pull down the lower eyelid. Apply 1–2 drops into the eye.

General guidance: Use 3–4 times daily for ear conditions. Use up to 6 times daily for eye conditions if prescribed. Do not use for longer than 7 days unless advised. Avoid touching the dropper tip.

These are prescription ear medications, so correct use is important for recovery. The exact dosing schedule will depend on your prescription.

Who Can Use Sofradex Ear/Eye Drops?

Sofradex is suitable for adults and some older children when prescribed for infection and inflammation. It may be recommended if you have a bacterial ear infection, experience ear swelling, pain, or irritation, or need combined ear care with antibiotic and steroid treatment. A proper assessment is always required before starting treatment.

Sofradex is not suitable in certain conditions where steroid or antibiotic use may cause harm. You should not use it if you are allergic to dexamethasone, framycetin, or gramicidin, have a viral or fungal infection, have a damaged or perforated eardrum, have undiagnosed red eye or serious eye conditions, or wear contact lenses (for eye use). If you are unsure, suitability should always be checked before use.

Possible Side Effects of Sofradex Ear/Eye Drops

Like all medicines, Sofradex can cause side effects.

Common Side Effects:

  • Mild irritation or burning in the ear or eye
  • Itching or discomfort at the application site
  • Temporary blurred vision (eye use)

Serious Side Effects:

  • Allergic reactions such as swelling or rash
  • Hearing problems, particularly if used when the eardrum is perforated
  • Vision changes or increased eye pressure
  • Hormonal effects with prolonged use

If serious symptoms occur, medical attention is required. Take care if you use other optic drops or ear treatments, are using other steroid-containing treatments, or have underlying ear or eye conditions. Avoid prolonged use without review, and speak up if symptoms do not improve within a few days.

Why Do People Choose Sofradex Ear/Eye Drops?

Sofradex is often chosen because it treats both infection and inflammation in one treatment. People prefer this option because it combines antibacterial ear drops with a steroid, reduces swelling, pain, and irritation quickly, targets bacterial causes effectively, is widely used for ear infection treatment, and provides focused ear care in a single solution. This makes it a practical choice for more uncomfortable or persistent eye and ear conditions.

How Does the Ordering Process Work at Pharmacy Planet?

Getting Sofradex drop from Pharmacy Planet is simple and clinically reviewed.

  1. Complete an online consultation and provide details about your symptoms and health history.
  2. A UK-registered prescriber checks if this treatment is suitable.
  3. If approved, your treatment is delivered safely to your address.
Sofradex Ear/Eye Drops

Sofradex combines antibiotics with a steroid to treat bacterial ear and eye infections together with inflammation, calming irritation inside the ear canal or eye while clearing the underlying infection.

Used for ear infection treatment (especially outer ear infections/otitis externa), inflamed ear canals with pain/itching/swelling, and conditions needing combined antibacterial and anti-inflammatory treatment for the ear or eye.

Contains framycetin (antibiotic killing bacteria), gramicidin (broadens antibacterial action), and dexamethasone (corticosteroid reducing swelling/redness/discomfort) — effective as both an ocular antibiotic and steroid ear treatment.

Ear: 2–3 drops, head tilted for a few minutes, 3–4 times daily

Eye: 1–2 drops, up to 6 times daily if prescribed

Do not use longer than 7 days unless advised, and avoid touching the dropper tip.

Suitable for adults and some older children with bacterial ear infections, swelling/pain/irritation, or needing combined antibiotic and steroid ear care.

Not suitable for allergy to dexamethasone/framycetin/gramicidin, viral or fungal infection, damaged/perforated eardrum, undiagnosed red eye or serious eye conditions, or contact lens wearers (eye use).

Common: Mild irritation/burning in ear or eye, itching/discomfort at application site, temporary blurred vision (eye use)

Serious: Allergic reactions (swelling/rash), hearing problems (especially with perforated eardrum), vision changes/increased eye pressure, hormonal effects with prolonged use

Seek medical attention for serious symptoms. Avoid prolonged use without review.

Treats infection and inflammation together, reduces swelling/pain/irritation quickly, targets bacterial causes effectively, and provides focused ear care in a single solution.

Getting Sofradex drop from Pharmacy Planet is simple and clinically reviewed.

  1. Complete an online consultation and provide details about your symptoms and health history.
  2. A UK-registered prescriber checks if this treatment is suitable.
  3. If approved, your treatment is delivered safely to your address.
Frequently Asked Questions

Sofradex ear drops are used to treat outer ear infections. They reduce swelling, pain, and itching while the antibiotics clear the bacteria causing the infection.

Many people notice relief within a couple of days. Pain and irritation usually improve first, but you should continue using it for the full course.

Yes, it may be prescribed if the blockage or itching is caused by inflammation or infection. It is not suitable for wax build-up alone.

Yes, Sofradex can be used in the eye if prescribed. It is used for inflamed eyes where there is also a risk of bacterial infection.

It is both. It contains antibiotics (framycetin and gramicidin) to treat infection and a steroid (dexamethasone) to reduce inflammation.

No, Sofradex should not be used if you have a damaged eardrum. It can lead to serious complications, including hearing problems.

It is usually used for up to 7 days unless advised otherwise. Using it for longer without review can increase the risk of side effects.

If there is no improvement within a few days or symptoms get worse, you should seek further advice. You may need a different treatment.

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Review By

HARMINDER ‘HARMY’ KAUR

Last Updated On : Mar 13 2026

BSc(hons) Pharmacy

GPhC Number: 2061107

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Authored By

GURDEV SEHMI

Last Reviewed On : Mar 23 2026

BSc Pharm, MRPharmS, Independent Prescriber, Superintendent Pharmacist, Clinical Lead

GPhC Number: 2050925