Sofradex/Dexamethasone + Framycetin + Gramicidin

Sofradex is a combined preparation for the current application in ophthalmology and otorhinolaryngology. The composition of the medicine includes two antibiotics and glucocorticosteroid, because the medicine has anti-inflammatory, bactericidal, and antiallergic action, eliminating pain, itching, and lacrimation. In ophthalmology, Sofradex is used to treat bacterial eye infections caused by microorganisms that are sensitive to the action of the medicine.

Sofradex ear/eye drops contain per ml: dexamethasone sodium metasulfobenzoate ester, which corresponds to 0.5 mg dexamethasone, 5 mg framycetin sulfate, and 0.05 mg gramicidin. Sofradex ear ointment contains per gram: 0.5 mg dexamethasone, 5 mg framycetin sulfate, and 0.05 mg gramicidin. The drops contain 5 mg/ml of phenyl ethyl alcohol as a preservative.

This Eye and Ear treatment medication work due to its main active ingredients, Framycetin sulfate is an antibiotic from the aminoglycoside group, it acts as a bactericide. It has a broad spectrum of antibacterial action, it is active against gram-positive microorganisms, including Staphylococcus aureus and gram-negative microorganisms, the most clinically significant (E. coli, Diz., Proteus, etc.). It is not effective for streptococci. It does not affect pathogenic fungi, viruses, anaerobic flora. The stability of microorganisms to the framycetin sulfate develops slowly. Gramicidin - has a bactericidal and bacteriostatic effect, widens the spectrum of Framicetin's antimicrobial action due to its activity against staphylococci, as it also has an anti-staphylococcal effect.

Dexamethasone - GCS, which has a pronounced anti-inflammatory, anti-allergic, and desensitizing effect. Dexamethasone suppresses inflammatory processes, inhibiting the release of inflammatory mediators, the migration of mast cells, and reducing the permeability of capillary tubes. When infused into the eyes they reduce pain, cremation, lacrimation, photophobia. When infused into the ears it reduces the symptoms of ear otitis externa (redness of the skin, pain, itching, burning in the external ear canal, feeling of the congested ear).

The main Sofradex uses happens due to the two antibiotics and a corticosteroid it contains and that is designed for use in diseases of the external ear canal. Framycetin sulfate is a broad-spectrum bactericidal antibiotic that belongs to the group of aminoglycosides; It is effective against staphylococci, protein strains, Escherichia coli and Streptococcus faecalis, among others. Most other streptococcal strains, as well as Pseudomonas aeruginosa, are resistant. Gramicidin is effective against gram-positive bacteria, including streptococci. Dexamethasone is a weak-acting corticosteroid on the skin that suppresses inflammatory symptoms.

This medication is for use in the eyes or ears only; it should not be taken orally. Wash your hands before using the drops. Follow these links for tips on using eye drops and using ear drops.

It is important to follow the instructions given by your doctor. If you use the eye drops, the usual dose is one or two drops in the affected eye up to six times a day. For use in the ears, the usual dose is two or three drops in the affected ear (s) three or four times a day.

You should not use these drops for more than seven days unless your doctor tells you to. Consult your doctor if after seven days of treatment with this medicine there is little or no improvement in your symptoms, or your symptoms worsen despite treatment.

These drops contain a preservative that helps keep the drops sterile while in use. However, the drops should be discarded four weeks after opening the bottle for the first time, because at this time they may have been contaminated with germs that could cause eye or ear infections. It may be helpful to write the opening date on the package. Dispose of carefully, preferably returning to your pharmacy.

In addition to the desired effect, this can cause drug side effects. The main Sofradex side effects are the following.

Rare (affects 1 to 10 in 100 people)

Stinging or burning sensation immediately after dripping. This quickly disappears again. Do you continue to suffer? Then consult your doctor.

Hypersensitivity to this drug. You will notice this from increased itching, redness, and swelling. Contact your doctor if your symptoms get worse. If you are hypersensitive, tell the pharmacist. The pharmacy team can then make sure that you do not get this medicine or similar antibiotics again.

Very rare (affects less than 1 in 100 people)

Fungal infection of the ear canal. This can occur after several weeks of use if it disturbs the normal balance between bacteria and fungi in the ears. You are less likely to notice this type of infection because the adrenal cortex hormone dexamethasone suppresses symptoms of the infection such as redness, swelling and itching. You may see a white deposit in the ear canal. Consult your doctor if your symptoms get worse.

When used for a long time: thinning of the eardrum, which can cause it to break. Therefore, do not use it longer than 7 days. Unless your doctor has told you to.

Ringing in the ears or spinning. This side effect can occur if the ear drops reach sensitive areas in the ear. Ultimately, this can lead to deafness or persistent ringing in the ears.

Therefore, stop using if you have these complaints and contact your doctor.

People with a hole or tube in the eardrum are more at risk. Discuss this with your doctor. Another drug may be more suitable for you. The risk is small for a middle ear infection. This is because the middle ear is often swollen. As a result, the ear drops do not reach sensitive areas.

You can buy Sofradex Eye/Ear drops online through one of the UK’s leading online pharmacies, Pharmacy Planet. It's easy and convenient. You will need to fill out a short assessment and the item will be delivered directly to your door. If you want to buy Sofradex online, use Pharmacy Planet, a UK pharmacy you can trust.