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Once-Daily Oral GLP-1 Treatment for Weight Management
Foundayo is the brand name for orforglipron, a once-daily oral GLP-1 medicine developed by Eli Lilly and authorised in the UK for weight management in eligible adults.
Unlike injectable GLP-1 treatments, Foundayo is supplied as a once-daily tablet. It can be taken with or without food and is used alongside a reduced-calorie diet and increased physical activity.
Your suitability for treatment will be assessed by a qualified UK clinician before any medicine is prescribed.
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Foundayo is the brand name for orforglipron, a once-daily GLP-1 tablet developed by Lilly.
The standout difference is simple: it is swallowed rather than injected. It can be taken at any time of day, with or without food, and there are no special water restrictions. For people who are not keen on needles, that may make a daily tablet worth discussing with a clinician.
Foundayo has been authorised and is now in the UK on Pharmacy Planet for weight loss and long-term weight management in eligible adults. It has also been authorised to improve blood sugar control in adults with type 2 diabetes when it is not controlled well enough.
It is a prescription-only medicine and is intended to be used alongside a reduced-calorie diet and increased physical activity. In other words, the tablet can offer support, but it does not have to do the whole job alone, and neither do you.
For weight management, Foundayo is authorised for adults who have:
A weight-related condition could include high blood pressure, abnormal cholesterol levels, obstructive sleep apnoea or cardiovascular disease.
BMI is only the starting point. A Pharmacy Planet clinician will also consider your medical history, current medicines, previous weight loss treatments and any side effects you have experienced. This helps them recommend an option that fits you as a person, rather than simply matching you to a number.
Good to know: Meeting the eligibility criteria does not guarantee a prescription. Treatment is only supplied when a qualified prescriber decides it is safe and appropriate for you.
Foundayo prices at Pharmacy Planet start from £60 using the discount code NEW30 at checkout for a one-month supply, with the price increasing depending on the strength you have been prescribed.
Our current Foundayo prices are:
| Foundayo strength | Price | Supply |
|---|---|---|
| 0.8 mg | £90 (£60 Using Discount Code NEW30) | 30 tablets |
| 2.5 mg | £109 (£79 Using Discount Code NEW30) | 30 tablets |
| 5.5 mg | £119 (£89 Using Discount Code NEW30) | 30 tablets |
| 9 mg | £139 (£109 Using Discount Code NEW30) | 30 tablets |
| 14.5 mg | £159 (£129 Using Discount Code NEW30) | 30 tablets |
| 17.2 mg | £169 (£139 Using Discount Code NEW30) | 30 tablets |
At Pharmacy Planet, we want to keep weight loss treatment as affordable as possible, without cutting corners when it comes to your care. That’s why we keep our prices consistently low across the board and we do bundle packs to make your weight loss journey as smooth as possible, and even provide discounts and price match guarantees to bring that cost down even lower. Every order is reviewed by a qualified UK prescriber, so while keeping the price down is important to us, making sure your treatment remains safe and suitable always comes first.
After all, your weight loss journey might be a long-term one, but that doesn’t mean your treatment needs to cost the earth.
Foundayo copies the effects of GLP-1, a hormone your body naturally releases after you eat. GLP-1 is involved in appetite, digestion and blood sugar control.
By acting on the same receptors, Foundayo may help you feel fuller for longer, reduce hunger and make cravings easier to manage. For some people, this can make smaller portions and everyday food choices feel a little less demanding.
It is not a fat-burning tablet or a quick fix. Its role is to make sustainable changes more manageable while you work towards your longer-term health goals.
Foundayo was studied in ATTAIN-1, a Phase 3 trial involving 3,127 adults living with obesity, or overweight alongside a weight-related health condition. The participants did not have type 2 diabetes.
After 72 weeks, people taking the highest studied dose lost an average of 12.4% of their starting body weight, compared with 0.9% among people taking a placebo. Everyone in the study also received support with diet and physical activity.
These figures are study averages, not a personal forecast. Some people lost more, others lost less, and results can be affected by the dose reached, how long treatment continues, side effects and lifestyle changes.
Foundayo is available in six strengths: 0.8 mg, 2.5 mg, 5.5 mg, 9 mg, 14.5 mg and 17.2 mg.
Treatment starts at 0.8 mg once a day. After at least 30 days, the dose is usually increased to 2.5 mg and then to 5.5 mg. If needed, it may later be increased through 9 mg, 14.5 mg and 17.2 mg, with at least 30 days at each dose.
| Stage of treatment | Usual daily dose |
|---|---|
| First 30 days | 0.8 mg |
| Next 30 days | 2.5 mg |
| Following 30 days | 5.5 mg |
| Later dose levels, if suitable | 9 mg, 14.5 mg or 17.2 mg |
| Maximum dose | 17.2 mg |
This does not mean everyone will follow exactly the same path or need the highest dose. Your clinician will consider how well the treatment is working and whether you are experiencing side effects before recommending another increase.
Moving up gradually is important because digestive side effects can be more noticeable when treatment begins or the dose changes. Giving your body time to adjust can make treatment easier to manage.
A higher dose is not automatically a better dose. The aim is to find a dose that supports your progress while remaining comfortable and appropriate for you.
Take Foundayo once a day, following the instructions provided by your prescriber.
You can take the tablet at any time of day, with or without food. Unlike some other oral GLP-1 medicines, you do not need to take it on an empty stomach or wait before eating and drinking.
Swallow the tablet whole. Do not split, crush or chew it, and never take more than one tablet in a day unless your prescriber has given you different instructions.
Choosing a time that fits naturally into your routine may make the tablet easier to remember. This could be with breakfast, during your lunch break or as part of your evening routine.
Keep it simple: There is no need to plan meals around Foundayo. The most important thing is to take it once daily and follow your prescribed dose.
If you forget to take Foundayo, take the missed dose as soon as you remember. Do not take two doses together or take an additional tablet to make up for the one you missed.
Since Foundayo can be taken with or without food, it does not matter whether you have already eaten when you remember your dose.
If you have missed seven or more doses in a row, speak to your prescriber before restarting. They may advise returning to a lower dose and building up gradually again. This can help reduce the chance of digestive side effects.
If you are ever unsure what to do, check the Patient Information Leaflet or contact your clinical team for advice.
No. The maximum Foundayo dose is 17.2 mg once daily, but not everyone will need or be suitable for this dose.
Your maintenance dose will depend on your response to treatment, your progress and any side effects you experience. Some people may remain on a lower dose if it is working well for them, while others may be advised to increase gradually.
Do not increase your dose yourself, even if your weight loss has slowed or you feel that the medicine is not working as strongly. Weight can change at different rates, and taking more than prescribed may increase the risk of side effects.
Your Pharmacy Planet clinician will help you decide whether remaining at your current dose or moving to the next level is the right step.
These treatments may appear in the same weight management conversation, but there are some useful differences in how they are taken.
| Treatment | Active ingredient | How it is taken |
|---|---|---|
| Foundayo | Orforglipron | Once-daily tablet, with or without food |
| Wegovy tablets | Semaglutide | Once-daily tablet, taken on an empty stomach |
| Wegovy injections | Semaglutide | Once-weekly injection |
| Mounjaro | Tirzepatide | Once-weekly injection |
Foundayo and Wegovy tablets are both taken once a day, but the routines are different. Foundayo can be taken with or without food, while Wegovy tablets need to be taken after an overnight fast, followed by a 30-minute wait before food, drink or other tablets. Wegovy injections and Mounjaro are taken once a week.
That does not make one option better for everyone. Some people prefer a daily tablet, while others would rather think about treatment once a week.
A Pharmacy Planet clinician can look at your health, preferences and previous treatment experience to decide which available option may suit you. Results from separate clinical trials should not be treated as a like-for-like comparison because the people, doses and methods used can differ.
Like all medicines, Foundayo can cause side effects. Stomach and digestive symptoms are the most common and may be more noticeable when you first start or move up to a higher dose.
Common side effects include:
These effects may settle as your body gets used to treatment. If they are persistent, difficult to manage or make it hard to eat and drink, contact your clinician rather than trying to push through them alone.
Some side effects can be serious. Get urgent medical help if you develop severe and persistent stomach pain, particularly if it spreads to your back, or signs of a serious allergic reaction such as swelling of your face or throat or difficulty breathing.
Always read the Patient Information Leaflet supplied with your medicine, as it contains the full list of side effects and advice on what to do. You can also report suspected side effects through the MHRA Yellow Card scheme.
Foundayo will not be suitable for everyone. You should not take it if you are allergic to orforglipron or any of the other ingredients in the tablet. It should not be used during pregnancy, and it should not be combined with another GLP-1 medicine unless a clinician has specifically told you to do so.
Your clinician will need to know if you have previously experienced pancreatitis, serious digestive problems, kidney or liver problems, gallbladder problems or diabetic eye disease. This does not always mean you cannot use treatment, but it helps your clinician make a safe decision.
Be open about your health and any previous reactions to weight loss medicines during your Pharmacy Planet consultation. The questions are there to protect you, not to judge you.
Foundayo may affect how some tablets are absorbed because it changes the speed at which food and medicine move through the stomach. It can also increase the risk of low blood sugar when taken with insulin or certain diabetes medicines.
Tell your clinician about everything you use, including prescription medicines, over-the-counter treatments, vitamins, herbal remedies and other weight management products.
Foundayo may make the oral contraceptive pill less effective. Current prescribing information advises people taking the pill to use a non-oral method of contraception or add a barrier method for 30 days after starting treatment and for 30 days after each dose increase.
Do not stop or change your contraception without speaking to a healthcare professional. Your clinician can help you find an option that feels practical and gives you the protection you need.
Foundayo should not be used during pregnancy. Tell your clinician if you are pregnant, think you may be pregnant, are planning a pregnancy, are breastfeeding or are having fertility treatment. If you become pregnant while taking Foundayo, stop taking it and contact your prescriber promptly for advice.
The MHRA authorised Foundayo in the UK on 10 August 2026 for weight management in eligible adults and for type 2 diabetes. However, authorisation does not mean it will appear on pharmacy shelves straight away.
Foundayo is not currently available through the NHS. NICE will need to assess it before deciding whether it should be recommended for routine NHS use.
You can now buy Foundayo online in the UK on Pharmacy Planet. Just fill in a clinical consultation and once your order has been approved from a qualified UK prescriber, you'll be able to start your weight loss journey with Foundayo. Our aim is to make the process clear and supportive, from checking whether treatment is right for you to helping you understand what comes next.
Please stay safe: Only obtain GLP-1 medicines from a registered pharmacy with a valid prescription. Products sold through unregulated websites or social media may be fake, unsafe or unsuitable for you.
Foundayo is the brand name for orforglipron, a once-daily GLP-1 tablet developed by Lilly.
The standout difference is simple: it is swallowed rather than injected. It can be taken at any time of day, with or without food, and there are no special water restrictions. For people who are not keen on needles, that may make a daily tablet worth discussing with a clinician.
Foundayo has been authorised and is now in the UK on Pharmacy Planet for weight loss and long-term weight management in eligible adults. It has also been authorised to improve blood sugar control in adults with type 2 diabetes when it is not controlled well enough.
It is a prescription-only medicine and is intended to be used alongside a reduced-calorie diet and increased physical activity. In other words, the tablet can offer support, but it does not have to do the whole job alone, and neither do you.
For weight management, Foundayo is authorised for adults who have:
A weight-related condition could include high blood pressure, abnormal cholesterol levels, obstructive sleep apnoea or cardiovascular disease.
BMI is only the starting point. A Pharmacy Planet clinician will also consider your medical history, current medicines, previous weight loss treatments and any side effects you have experienced. This helps them recommend an option that fits you as a person, rather than simply matching you to a number.
Good to know: Meeting the eligibility criteria does not guarantee a prescription. Treatment is only supplied when a qualified prescriber decides it is safe and appropriate for you.
Foundayo prices at Pharmacy Planet start from £90 for a one-month supply, with the price increasing depending on the strength you have been prescribed.
Our current Foundayo prices are:
| Foundayo strength | Price | Supply |
|---|---|---|
| 0.8 mg | £90 | 30 tablets |
| 2.5 mg | £109 | 30 tablets |
| 5.5 mg | £119 | 30 tablets |
| 9 mg | £139 | 30 tablets |
| 14.5 mg | £159 | 30 tablets |
| 17.2 mg | £169 | 30 tablets |
At Pharmacy Planet, we want to keep weight loss treatment as affordable as possible, without cutting corners when it comes to your care. That’s why we keep our prices consistently low across the board and we do bundle packs to make your weight loss journey as smooth as possible. Every order is reviewed by a qualified UK prescriber, so while keeping the price down is important to us, making sure your treatment remains safe and suitable always comes first.
After all, your weight loss journey might be a long-term one, but that doesn’t mean your treatment needs to cost the earth.
Foundayo copies the effects of GLP-1, a hormone your body naturally releases after you eat. GLP-1 is involved in appetite, digestion and blood sugar control.
By acting on the same receptors, Foundayo may help you feel fuller for longer, reduce hunger and make cravings easier to manage. For some people, this can make smaller portions and everyday food choices feel a little less demanding.
It is not a fat-burning tablet or a quick fix. Its role is to make sustainable changes more manageable while you work towards your longer-term health goals.
Foundayo was studied in ATTAIN-1, a Phase 3 trial involving 3,127 adults living with obesity, or overweight alongside a weight-related health condition. The participants did not have type 2 diabetes.
After 72 weeks, people taking the highest studied dose lost an average of 12.4% of their starting body weight, compared with 0.9% among people taking a placebo. Everyone in the study also received support with diet and physical activity.
These figures are study averages, not a personal forecast. Some people lost more, others lost less, and results can be affected by the dose reached, how long treatment continues, side effects and lifestyle changes.
Foundayo is available in six strengths: 0.8 mg, 2.5 mg, 5.5 mg, 9 mg, 14.5 mg and 17.2 mg.
Treatment starts at 0.8 mg once a day. After at least 30 days, the dose is usually increased to 2.5 mg and then to 5.5 mg. If needed, it may later be increased through 9 mg, 14.5 mg and 17.2 mg, with at least 30 days at each dose.
| Stage of treatment | Usual daily dose |
|---|---|
| First 30 days | 0.8 mg |
| Next 30 days | 2.5 mg |
| Following 30 days | 5.5 mg |
| Later dose levels, if suitable | 9 mg, 14.5 mg or 17.2 mg |
| Maximum dose | 17.2 mg |
This does not mean everyone will follow exactly the same path or need the highest dose. Your clinician will consider how well the treatment is working and whether you are experiencing side effects before recommending another increase.
Moving up gradually is important because digestive side effects can be more noticeable when treatment begins or the dose changes. Giving your body time to adjust can make treatment easier to manage.
A higher dose is not automatically a better dose. The aim is to find a dose that supports your progress while remaining comfortable and appropriate for you.
Take Foundayo once a day, following the instructions provided by your prescriber.
You can take the tablet at any time of day, with or without food. Unlike some other oral GLP-1 medicines, you do not need to take it on an empty stomach or wait before eating and drinking.
Swallow the tablet whole. Do not split, crush or chew it, and never take more than one tablet in a day unless your prescriber has given you different instructions.
Choosing a time that fits naturally into your routine may make the tablet easier to remember. This could be with breakfast, during your lunch break or as part of your evening routine.
Keep it simple: There is no need to plan meals around Foundayo. The most important thing is to take it once daily and follow your prescribed dose.
If you forget to take Foundayo, take the missed dose as soon as you remember. Do not take two doses together or take an additional tablet to make up for the one you missed.
Since Foundayo can be taken with or without food, it does not matter whether you have already eaten when you remember your dose.
If you have missed seven or more doses in a row, speak to your prescriber before restarting. They may advise returning to a lower dose and building up gradually again. This can help reduce the chance of digestive side effects.
If you are ever unsure what to do, check the Patient Information Leaflet or contact your clinical team for advice.
No. The maximum Foundayo dose is 17.2 mg once daily, but not everyone will need or be suitable for this dose.
Your maintenance dose will depend on your response to treatment, your progress and any side effects you experience. Some people may remain on a lower dose if it is working well for them, while others may be advised to increase gradually.
Do not increase your dose yourself, even if your weight loss has slowed or you feel that the medicine is not working as strongly. Weight can change at different rates, and taking more than prescribed may increase the risk of side effects.
Your Pharmacy Planet clinician will help you decide whether remaining at your current dose or moving to the next level is the right step.
These treatments may appear in the same weight management conversation, but there are some useful differences in how they are taken.
| Treatment | Active ingredient | How it is taken |
|---|---|---|
| Foundayo | Orforglipron | Once-daily tablet, with or without food |
| Wegovy tablets | Semaglutide | Once-daily tablet, taken on an empty stomach |
| Wegovy injections | Semaglutide | Once-weekly injection |
| Mounjaro | Tirzepatide | Once-weekly injection |
Foundayo and Wegovy tablets are both taken once a day, but the routines are different. Foundayo can be taken with or without food, while Wegovy tablets need to be taken after an overnight fast, followed by a 30-minute wait before food, drink or other tablets. Wegovy injections and Mounjaro are taken once a week.
That does not make one option better for everyone. Some people prefer a daily tablet, while others would rather think about treatment once a week.
A Pharmacy Planet clinician can look at your health, preferences and previous treatment experience to decide which available option may suit you. Results from separate clinical trials should not be treated as a like-for-like comparison because the people, doses and methods used can differ.
Like all medicines, Foundayo can cause side effects. Stomach and digestive symptoms are the most common and may be more noticeable when you first start or move up to a higher dose.
Common side effects include:
These effects may settle as your body gets used to treatment. If they are persistent, difficult to manage or make it hard to eat and drink, contact your clinician rather than trying to push through them alone.
Some side effects can be serious. Get urgent medical help if you develop severe and persistent stomach pain, particularly if it spreads to your back, or signs of a serious allergic reaction such as swelling of your face or throat or difficulty breathing.
Always read the Patient Information Leaflet supplied with your medicine, as it contains the full list of side effects and advice on what to do. You can also report suspected side effects through the MHRA Yellow Card scheme.
Foundayo will not be suitable for everyone. You should not take it if you are allergic to orforglipron or any of the other ingredients in the tablet. It should not be used during pregnancy, and it should not be combined with another GLP-1 medicine unless a clinician has specifically told you to do so.
Your clinician will need to know if you have previously experienced pancreatitis, serious digestive problems, kidney or liver problems, gallbladder problems or diabetic eye disease. This does not always mean you cannot use treatment, but it helps your clinician make a safe decision.
Be open about your health and any previous reactions to weight loss medicines during your Pharmacy Planet consultation. The questions are there to protect you, not to judge you.
Foundayo may affect how some tablets are absorbed because it changes the speed at which food and medicine move through the stomach. It can also increase the risk of low blood sugar when taken with insulin or certain diabetes medicines.
Tell your clinician about everything you use, including prescription medicines, over-the-counter treatments, vitamins, herbal remedies and other weight management products.
Foundayo may make the oral contraceptive pill less effective. Current prescribing information advises people taking the pill to use a non-oral method of contraception or add a barrier method for 30 days after starting treatment and for 30 days after each dose increase.
Do not stop or change your contraception without speaking to a healthcare professional. Your clinician can help you find an option that feels practical and gives you the protection you need.
Foundayo should not be used during pregnancy. Tell your clinician if you are pregnant, think you may be pregnant, are planning a pregnancy, are breastfeeding or are having fertility treatment. If you become pregnant while taking Foundayo, stop taking it and contact your prescriber promptly for advice.
The MHRA authorised Foundayo in the UK on 10 August 2026 for weight management in eligible adults and for type 2 diabetes. However, authorisation does not mean it will appear on pharmacy shelves straight away.
Foundayo is not currently available through the NHS. NICE will need to assess it before deciding whether it should be recommended for routine NHS use.
You can now buy Foundayo online in the UK on Pharmacy Planet. Just fill in a clinical consultation and once your order has been approved from a qualified UK prescriber, you'll be able to start your weight loss journey with Foundayo. Our aim is to make the process clear and supportive, from checking whether treatment is right for you to helping you understand what comes next.
Please stay safe: Only obtain GLP-1 medicines from a registered pharmacy with a valid prescription. Products sold through unregulated websites or social media may be fake, unsafe or unsuitable for you.
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* Results are not directly comparable because studies differed. Figures are approximate and treatment was combined with a calorie deficit and increased physical activity. Results vary depending on the individual.
You can now buy Foundayo online in the UK from Pharmacy Planet, with prices starting from just £60 using discount code NEW30. With all strengths available, we’re excited to help you start your weight loss journey or continue making progress with this brand new treatment.
At Pharmacy Planet, we believe getting the support you need shouldn’t mean worrying about the cost of your treatment. By keeping Foundayo affordable and supporting you along the way, you can focus on what really matters: making progress that works for you. More support, more affordable prices and one less thing to worry about. Sounds like a win to us!
No, Foundayo can be taken once a day, at any time, with or without food. There are also no special rules around how much water you need to drink when taking it.
The tablet should be swallowed whole rather than crushed, broken or chewed. Try to take it at around the same time each day, as this may make it easier to remember.
Always follow the instructions supplied with your medicine and any advice given by our prescribing team.
Foundayo works on GLP-1 receptors involved in appetite and feelings of fullness. This may help you feel less hungry, feel satisfied after smaller meals and experience fewer cravings.
“Food noise” is an informal term people sometimes use to describe frequent or distracting thoughts about eating. Although it is not a medical diagnosis, some patients may find these thoughts easier to manage when their appetite reduces.
Everyone responds differently, so changes in hunger and cravings will vary from person to person.
When you lose weight, some of that loss can come from lean tissue, including muscle—not only body fat. This can happen with any weight-loss approach and is not unique to Foundayo.
Eating a balanced diet with enough protein and including suitable strength-based activity may help you look after your muscle mass while losing weight. The right approach will depend on your health, mobility and nutritional needs.
Speak to your Pharmacy Planet clinician if you are losing weight very quickly, struggling to eat enough or beginning to feel unusually weak. They can review your progress and help you find an approach that feels safe and manageable.
It is possible to regain some weight after stopping a GLP-1 treatment. Your appetite may increase again when the medicine is no longer having an effect, which can make weight maintenance more challenging.
This does not mean you have failed. Weight management is rarely a straight line, and many people need ongoing support to maintain their progress.
Before stopping Foundayo, speak to your prescriber. They can help you consider your next steps and build a longer-term plan around food, activity and any continuing treatment needs.
Foundayo is intended to support long-term weight management rather than provide a quick fix. However, this does not mean everyone will take it for the same length of time.
Your treatment will need to be reviewed regularly to check that it is working, that any side effects remain manageable and that it is still suitable for you.
Your Pharmacy Planet clinician can support you through these reviews and help you decide whether continuing, changing or stopping treatment is the right next step.
Switching may be possible, but it must be planned with a qualified prescriber.
Your clinician will consider your current treatment and dose, when you took your last injection, your progress and any side effects before advising you what to do next.
Foundayo should not be taken alongside another GLP-1 medicine unless you have been specifically told to do so. Never overlap treatments or create your own switching schedule.
Answer a few questions on your health and your fitness goals.
Our clinicians will review your clinical questionnaire to make sure treatment is right for you.
Once approved, you will access our wealth of experience and resources curated by our team and begin your clinical weight loss journey.
Start your weight loss journey heading in the right direction. Our team are here to help. Whether you’re unsure about which medicine is right for you or need help navigating the world of weight loss drugs, our team are on hand to help you make the right decision. We can put you in touch with one of our experienced weight loss clinicians so you can be sure you’re making the best decision with the most accurate information.
To get in touch, contact our Customer Service team on 0800 978 8956 or email headoffice@pharmacyplanet.com.
MHRA – UK first in Europe to authorise orforglipron for weight management and type 2 diabetes
Electronic Medicines Compendium – Foundayo UK Patient Information Leaflet
MHRA – GLP-1 medicines for weight loss and diabetes: what you need to know
Eli Lilly – Foundayo clinical data and ATTAIN-1 body-composition analysis
Guy’s and St Thomas’ NHS Foundation Trust – Dietary advice for people taking weight-loss medicines
Review By
GURDEV SEHMI
Last Updated On : August 11 2026
BSc Pharm, MRPharmS, Independent Prescriber, Superintendent Pharmacist, Clinical Lead
GPhC Number: 2050925
Authored By
Ayesha Patel
Last Reviewed On : August 11 2026
MPharm (Hons), IPresc
GPhC Number: 2079407
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