Saxenda® is a weight loss medicine that contains the active substance liraglutide. It is similar to a naturally occurring hormone ...

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Saxenda® is a weight loss medicine that contains the active substance liraglutide. It is similar to a natural occurring hormone called glucagon-like peptide-1 (GLP-1) that is released from the intestine after a meal. Saxenda® works by acting on receptors in the brain that control your appetite, causing you to feel fuller and less hungry. This may help you eat less food and reduce your body weight.

Many studies have shown that patients using Saxenda lose significant amounts of weight over several weeks (usually around 10% body fat). ​

Usually, your treatment with Saxenda will start at a low dose which will be gradually increased over the first five weeks of treatment. 

Before beginning your treatment with Saxenda, please ensure you are familiar with how to administer the injections. Please watch this brief instructional video and review the patient information guide on the Saxenda website.

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What is Saxenda?

Saxenda is a daily injection indicated as an adjunct to a reduced-calorie diet, and increased physical activity, for weight management in adult patients

How does it work?

Saxenda contains the drug Liraglutide which is a medicine that falls into the Glucagon-like peptide 1 (GLP-1) agonist class of drugs.

GLP-1 is a naturally occurring hormone in the body that is released in response to food intake and acts as a physiological regulator of appetite. Saxenda is 97% similar to naturally occurring GLP-1.

Saxenda works in the hypothalamus, where it interacts with specific neurons involved in the regulation of appetite and food intake. Liraglutide sits on this receptor and causes changes to very important hormones involved in regulating body weight: insulin, leptin, and glucagon.

The effect of this medicine is thought to affect weight loss by the following mechanisms:

  • Reduces Leptin Resistance
  • Improves Insulin Sensitivity
  • Acts as a Glucagon Suppressant
  • Reduces Appetite
  • Increases Metabolism

Saxenda increases feelings of satiety feeling full) and decreases hunger. As a result of its mechanism of action, patients taking Saxenda feel satisfied and eat less food, leading to weight loss.

What are the benefits of taking it?

Liraglutide was originally developed to treat type II diabetes because it can help reduce insulin resistance but was soon found to have a dramatic effect on weight.

Many studies have shown that patients using Saxenda lose significant amounts of weight over several weeks (usually around 10% body fat). ​

In a clinical study of people taking Saxenda for 3 years:

  • 56% achieved significant weight loss at year 1, and
  • Approximately half of these patients maintained weight loss at 3 years when taking Saxenda added to a reduced-calorie meal plan and increased physical activity, compared with people not on the drug.

Reducing your waistline isn’t the only impact of weight loss. Taking off weight and keeping it off may help improve conditions such as high blood pressure and high cholesterol levels.

How do I use it and its dosage?

Always use this medicine exactly as your prescriber has told you. Check with your doctor, pharmacist, or nurse if you are not sure.

Before beginning your treatment with Saxenda

Side effects & precautions

Like all medicines, this Saxenda (Liraglutide) can cause side effects, although not everybody gets them.


Serious side effects

  • Some severe allergic reactions (anaphylaxis) have been reported rarely in patients using Saxenda. You should see your doctor straight away if you get symptoms such as breathing problems, swelling of face and throat and a fast heartbeat.

  • Cases of inflammation of the pancreas (pancreatitis) have been reported uncommonly in patients using Saxenda. Pancreatitis is a serious

Buying Saxenda online

You can buy Saxenda (Liraglutide) Injections online through one of the UK’s leading online pharmacies, Pharmacy Planet. It's easy and convenient. You will need to fill out a short assessment and the item will be delivered directly to your door. If you want to buy Saxenda Injections online, use Pharmacy Planet, a UK pharmacy you can trust.

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