Zolmitriptan is a headache medicine that narrows the blood vessels around the brain. Zolmitriptan also reduces substances in the body ...
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About Zolmitriptan Tablets

Zolmitriptan is used to treat migraines. It helps to relieve headache, pain, and other migraine symptoms (including nausea, vomiting, sensitivity to light/sound). Prompt treatment helps you return to your normal routine and may decrease your need for other pain medications. Zolmitriptan belongs to a class of drugs known as triptans. It affects a certain natural substance (serotonin) that causes narrowing of blood vessels in the brain. It may also relieve pain by affecting certain nerves in the brain.

Zolmitriptan does not prevent future migraines or lessen how often you get migraine attacks.

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What is Zolmitriptan?

Zolmitriptan belongs to a group of medicines called "selective serotonin (5HT1) agonists" and works in your brain to relieve migraine symptoms. Zolmitriptan is used for the treatment of migraine. You should not take Zolmitriptan to prevent migraines from appearing.

How does it work?

Zolmitriptan has been shown to be a selective 5-HT1B/1D receptor agonist that mediates vascular contraction. Zolmitriptan has a high affinity for recombinant human 5-HT1B and 5-HT1D receptors, and a modest affinity for 5-HT1A receptors. Zolmitriptan has no significant affinity or pharmacological activity for other 5-HT receptor subtypes (5-HT2, 5-HT3, 5-HT4) or adrenergic, histamine, muscarinic, or dopaminergic receptors.

What are the benefits of taking it?

Migraines are a form of headache that is generally known as symptoms such as sensitivity to light and noise, nausea, and vomiting. A so-called aura sometimes occurs before a migraine attack. This includes disturbances in the field of view, such as seeing asterisks, flashes of light, and a wavy image. Zolmitriptan is not suitable for preventing a migraine attack but is used for the acute treatment of an initial or existing migraine attack.

How do I use it and its dosage?

Always take Zolmitriptan exactly as your doctor has told you. Ask your doctor or pharmacist if you have doubts.

The normal zolmitriptan dosage is 2.5 mg to be taken as soon as a migraine starts. If you take it later it will still work.

If a 2.5 mg dose is not strong enough to treat your symptoms, your doctor may advise you to take a higher dose of 5 mg the next time you have a migraine. You are more likely to experience side effects at the highest dose (5 mg).

If your symptoms go away but then come back within 24 hours, you can take a second dose. However, you must wait at least two hours after the first dose.

The tablets should be swallowed whole with water. You should not take more than 2 doses in a 24 hour period. The maximum daily dose of your medicine is 10 mg. If you have liver problems or are taking other medications, your doctor may decide that you need a lower dose. Zolmitriptan is not recommended in patients younger than 18 years or older than 65 years.

Side effects & precautions

Like all medicines, this headache medicine can cause side effects, although not everybody gets them. Stop taking Zolmitriptan and contact your doctor immediately if you notice any of the following zolmitriptan side effects:

Rare (may affect up to 1 in 1,000 people):

  • Allergic reactions such as hives, swelling of the face, lips, mouth, tongue, or throat, or difficulty breathing.

Very rare (may affect up to 1 in 10,000 people):

  • Myocardial infarction or chest pain.
  • Intestinal and spleen infarction that can cause stomach pain or bloody diarrhea.

Other possible side effects:

Common (may affect up to 1 in 10 people):

  • Abnormal sensations such as tingling or itching, skin sensation, heat sensation, increased sensitivity to touch, or noise.
  • Dizziness or headache
  • Drowsiness
  • Palpitations (awareness of your heartbeat)
  • Pain in the abdomen, nausea, vomiting, dry mouth, dysphagia (difficulty swallowing)
  • Muscle weakness and muscle pain
  • Weakness
  • Heaviness, tension, pain, or pressure in the throat, neck, arms, legs, or chest.

Uncommon (may affect up to 1 in 100 people):

  • Fast heartbeat
  • Increase in blood pressure
  • Need to urinate more frequently or increase in the amount of urine produced.
  • Very rare (may affect up to 1 in 10,000 people):
  • Urgent need to urinate.

Warnings and precautions

Zolmitriptan should be used only when a clear diagnosis of migraine has been established. Like other acute migraine treatments, before treating headaches in previously undiagnosed migraine patients, and in migraine patients with atypical symptoms, care should be taken to exclude other potentially serious neurological conditions. Zolmitriptan is not indicated for use in hemiplegic, basilar, or ophthalmoplegic migraine. Strokes and other cerebrovascular events have been reported in patients treated with 5HT1B/1D agonists. Keep in mind that people with migraines may be at risk for certain cerebrovascular events.

Zolmitriptan should not be administered to patients with symptomatic Wolff-Parkinson-White syndrome or to arrhythmias associated with other accessory pathways of cardiac conduction.

As with other 5HT1B / 1D agonists, very rarely coronary vasospasm, angina pectoris, and myocardial infarction have been reported. Zolmitriptan should not be administered to patients with risk factors for ischemic heart disease (eg, smoking, hypertension, hyperlipidemia, diabetes mellitus, genetic inheritance) without prior cardiovascular evaluation. Special consideration should be given to postmenopausal women and men over the age of 40 with these risk factors. However, these evaluations may not identify all patients with heart disease and, in very rare cases, serious cardiac events have occurred in patients without underlying cardiovascular disease.

Zolmitriptan interactions

Interaction studies have been conducted with caffeine, ergotamine, dihydroergotamine, paracetamol, metoclopramide, pizotifen, fluoxetine, rifampin, and propranolol and no clinically relevant differences in the pharmacokinetics of zolmitriptan or its active metabolite have been observed. Data from healthy people suggest that there are no pharmacokinetic or clinically significant interactions between zolmitriptan and ergotamine. However, the increased risk of coronary vasospasm is a theoretical possibility, and concomitant administration is contraindicated. It is advisable to wait at least 24 hours after taking preparations containing ergotamine before administering zolmitriptan. Furthermore, it is advised to wait at least 6 hours after taking zolmitriptan before administering a product containing ergotamine

Buying Zolmitriptan online.

You can buy Zolmitriptan online through one of the UK’s leading online pharmacies, Pharmacy Planet. It's easy and convenient. You will need to fill out a short assessment and the item will be delivered directly to your door. If you want to buy migraine treatment medication online, use Pharmacy Planet, a UK pharmacy you can trust.
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