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Tolterodine XL/Detrusitol XL

Tolterodine XL and Detrusitol XL contains a drug that belongs to a group of medicines called antimuscarinics. Tolterodine is used to treat symptoms of overactive bladder syndrome. If you have overactive bladder syndrome, you may notice that you are not able to control your urine voluntarily, you feel a sudden and urgent need to urinate without warning and/or you increase the number of times you urinate during the day. Both Detrusitol XL and Tolterodine XL is a modified release formulation meaning that it releases the drug in controlled fashion and may not require administration as frequently as other Tolterodine formulations.

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Tolterodine XL/Detrusitol XL
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Please note that whilst you are able to request the medicine strength and size required,
we will only be able to send on approval from our in house pharmacist.

Starts at £32.00
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Price Comparison

Select your preferred options and see the best price

PackPrice (£)
Tolterodine XL (Generic)2mg28 Capsules32.00
Tolterodine XL (Generic)2mg56 Capsules57.00
Tolterodine XL (Generic)2mg84 Capsules82.00
Tolterodine XL (Generic)4mg28 Capsules34.00
Tolterodine XL (Generic)4mg56 Capsules59.00
Tolterodine XL (Generic)4mg84 Capsules84.00
Detrusitol XL4mg28 Capsules51.00
Detrusitol XL4mg56 Capsules94.00
Detrusitol XL4mg84 Capsules127.00

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Tolterodine XL (Detrusitol XL) Tablets for Incontinence and Urgency Symptoms

Tolterodine XL (sold under the brand name Detrusitol XL) is a bladder relaxant medicine used to treat overactive bladder symptoms, including urinary urgency, frequent urination and urge incontinence. As a modified-release (extended-release) tablet, Tolterodine XL releases medicine gradually throughout the day for stable bladder control. Most people use Tolterodine XL (Detrusitol XL) tablets when they prefer a once-daily OAB treatment that supports better bladder control and fewer disruptions from urinary symptoms.

You can order Tolterodine XL tablets online from Pharmacy Planet after a short consultation reviewed by one of our UK prescribers. If you need consistent OAB therapy for urgency, frequency or incontinence, Tolterodine XL tablets are worth considering.

What Are Tolterodine XL Tablets?

Tolterodine XL tablets are antimuscarinic medicines designed to treat overactive bladder and related urinary disorders. They are intended to reduce urinary urgency, frequent urination and involuntary leakage. The extended-release formulation means you usually take the tablet once a day for smoother symptom control.

Common uses for Tolterodine XL include treating urinary urgency, frequent daytime urination, and urge urinary incontinence, where leakage occurs before reaching the toilet. It is also taken to manage everyday overactive bladder symptoms with the convenience of a once-daily dose.

How Do Tolterodine XL Tablets Work?

Tolterodine works by blocking muscarinic receptors in the bladder muscle. This reduces involuntary bladder contractions and allows the bladder to store more urine comfortably. Because of this, urgency and frequent trips to the bathroom tend to become less frequent. The extended-release nature of Tolterodine XL maintains this effect steadily over 24 hours for consistent bladder relaxation and control.

How to Use Tolterodine XL Tablets

Take Tolterodine XL tablets exactly as directed by our UK prescriber. Swallow each tablet whole with water. Do not crush or chew.

Useful Tips for Best Results:

  • Take Tolterodine XL at the same time each day.
  • Swallow the tablet whole with a full glass of water.
  • Keep a regular daily schedule to help build consistent bladder control.
  • If you have side effects or doubts, speak to your prescriber.

The typical dose for adults is 4 mg once daily. For patients with kidney or liver issues, or if side effects occur, the dose may be reduced to 2 mg once daily. If you miss a dose, take it as soon as you remember, unless it's almost time for the next dose. Do not take two doses together.

Who Can Use Tolterodine XL Tablets?

Tolterodine XL may be suitable for:

  • Adults experiencing overactive bladder symptoms like urgency, frequent urination or urge incontinence.
  • People who prefer a once-daily bladder relaxant for an easier routine.

Tolterodine XL is not suitable for:

  • Anyone allergic to Tolterodine or any tablet ingredients.
  • People with untreated narrow-angle glaucoma or significant urinary retention/obstruction.
  • Individuals with severe ulcerative colitis, toxic megacolon or serious gastrointestinal disorders.
  • Those with serious liver or kidney disease (unless managed carefully).

Possible Side Effects of Tolterodine XL Tablets

Many people do not have serious problems, but like all medicines, Tolterodine XL can cause side effects in some people.

Common Side Effects:

  • Dry mouth
  • Headache

Other Possible Side Effects Include:

  • Dry or blurred vision, dizziness or drowsiness, constipation or digestive discomfort, difficulty urinating or reduced bladder emptying, occasional palpitations or faster heartbeat (in people prone to heart issues)

If you notice serious symptoms — for example, severe vision changes, urinary retention, chest pain, swelling, or allergic reactions — stop taking the medicine and contact your UK prescriber immediately.

Consultation and Prescription Process at Pharmacy Planet

Here's how you can request and receive your treatment at Pharmacy Planet:

  1. Complete the online consultation and share details about your urinary symptoms and general health.
  2. A UK prescriber reviews your information to decide whether Tolterodine XL tablets are right for you.
  3. If approved, your Tolterodine XL tablets are delivered discreetly to your door.
Tolterodine XL (Detrusitol XL) Tablets

Tolterodine XL is an extended-release bladder relaxant that treats overactive bladder symptoms including urinary urgency, frequent urination, and urge incontinence. It releases medicine gradually throughout the day for stable, once-daily bladder control.

Antimuscarinic extended-release medicines for overactive bladder. Reduce urinary urgency, frequent urination, and involuntary leakage. Once-daily dosing provides smoother symptom control compared to standard-release tablets.

Tolterodine blocks muscarinic receptors in the bladder muscle, reducing involuntary contractions and allowing the bladder to store more urine comfortably. The extended-release formulation maintains this effect steadily over 24 hours for consistent bladder relaxation and control.

Swallow whole with a full glass of water — do not crush or chew. Take at the same time each day. Typical dose: 4mg once daily (may be reduced to 2mg for kidney/liver issues). If a dose is missed, take it as soon as you remember unless close to next dose — never take two together.

May be suitable for:

  • Adults with OAB symptoms (urgency, frequent urination, urge incontinence) who prefer once-daily treatment.

Not suitable for:

  • Those allergic to Tolterodine, with untreated narrow-angle glaucoma, significant urinary retention/obstruction, severe ulcerative colitis, toxic megacolon, serious GI disorders, or serious liver/kidney disease.

Common: Dry mouth, headache

Other: Dry/blurred vision, dizziness/drowsiness, constipation/digestive discomfort, difficulty urinating, occasional palpitations or faster heartbeat

Stop taking and contact your prescriber immediately for severe vision changes, urinary retention, chest pain, swelling, or allergic reactions.

Tolterodine XL reduces sudden urinary urgency, cuts bathroom frequency, improves bladder control, and lowers the risk of accidental leakage — all with the convenience of once-daily dosing and steady extended relief for a more comfortable daily routine.

Here's how you can request and receive your treatment at Pharmacy Planet:

  1. Complete the online consultation and share details about your urinary symptoms and general health.
  2. A UK prescriber reviews your information to decide whether Tolterodine XL tablets are right for you.
  3. If approved, your Tolterodine XL tablets are delivered discreetly to your door.
Frequently Asked Questions

Tolterodine XL is used to treat overactive bladder symptoms like urgency, frequent urination and urge incontinence.

Some people find the XL version gentler because it releases medicine gradually over many hours.

Yes, you can take it with or without food. Remember to swallow the tablet whole with water.

Yes, but our prescriber may recommend a lower dose for elderly people, especially if kidney or liver function is reduced.

Yes. In case Tolterodine XL tablets do not suit you, other antimuscarinic medicines or different OAB treatments may be considered. Talk to your prescriber if Tolterodine XL does not fit your needs.

Yes, but only under prescriber guidance because the dosing and release pattern are different.

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Review By

GURDEV SEHMI

Last Updated On : Mar 13 2026

BSc Pharm, MRPharmS, Independent Prescriber, Superintendent Pharmacist, Clinical Lead

GPhC Number: 2050925

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Authored By

GURDEV SEHMI

Last Reviewed On : Mar 23 2026

BSc Pharm, MRPharmS, Independent Prescriber, Superintendent Pharmacist, Clinical Lead

GPhC Number: 2050925