Synalar is a hormonal treatment whose active ingredient is fluocinolone acetonide, which is a type of medicine known as a ...

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Synalar is a hormonal treatment whose active ingredient is fluocinolone acetonide, which is a type of medicine known as a topical corticosteroid (the hormone from the adrenal cortex). Synalar is used to reduce inflammation and relieve symptoms such as itching, pain, peeling, redness, and swelling.

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What is Synalar?

Synalar is an itching and seborrhea treatment medication classified as a Corticosteroid, which is indicated for inflammatory, allergic and pruritic diseases of the skin and mucosa, photodermatitis, psoriasis, atopic dermatitis, seborrheic; in severe cases, contact dermatitis, eczematous, lichen planus, pretibial myxedema, lipoid necrobiosis, erythroderma, neurodermatitis, nummular eczema, intertriginous psoriasis, nodular prurigo, discoid lupus erythematosus, chronic lichen simplex. Occlusive cure: apply topically on the lesions and cover them with a polyethylene sheet of slightly larger dimensions than those in the area to be treated. Fix the edges of the cover with an adhesive cloth to the adjacent skin, ensuring that the dressing is airtight. When psoriatic lesions appear on the hands, cover the hands with polyethylene gloves. The occlusive dressing must be kept for 24 hours, after which the treatment is removed and repeated.

How does it work?

Synalar is an immediate-acting topical cream with minimal mineralocorticoid effects, consisting of fluocinolone acetonide (synthetic fluorinated glucocorticoid derived from 16a-hydroxy-prednisolone) combined with neomycin, a bactericidal aminoglycoside antibiotic. It is classified in terms of potency, within class 3 (moderate potency), which allows long-term administration (6 weeks) with minimal adverse effects.

Effective levels of fluocinolone and neomycin are immediate, a useful feature when urgent therapeutic action is required. The Synalar topical synthetic steroid has been shown to have over 100 times the anti-inflammatory activity of hydrocortisone; Due to its mechanism of action in the anti-inflammatory, antiallergic and anaphylactic response, it increases the activation of genes that encode peptides such as lipocortin-1 and calpain / p11, both peptides have as their main target the enzyme phospholipase A2, responsible for the transformation of phospholipids of the arachidonic acid membrane, which acts as a substrate for two enzyme systems: cyclooxygenase and lipoxygenase.

What are the benefits of taking it?

Synalar contains two active ingredients: fluocinolone acetonide (glucocorticoid) that works against inflammation and ketocaine hydrochloride (local anesthetic) that reduces sensitivity in the area where it is applied.

Synalar belongs to a group of medicines called "anti-hemorrhoids" (against hemorrhoids) and is used:

  • in the local treatment of internal and external hemorrhoids
  • in inflammation and irritation of the skin in the anal area and near the anus (eczema and erythema)
  • in itching and burning in the anal area and near the anus
  • in lesions at the level of the anus with slow healing (anal fissures)
  • in the anal area before and after surgery (anorectal surgery).

How do I use it and its dosage?

This Ezcema and Psoriasis treatment medication is available in ointment, cream, and gel. Synalar cream is suitable for wet and oily skin areas, while the thicker and more oily consistency ointment format is suitable for areas with dry and flaky skin. Synalar gel is suitable for the scalp and other hairy areas of the skin.

Synalar cream, ointment, or gel should be applied sparingly and evenly to the affected area (s). Avoid contact with the eyes and wash your hands thoroughly after each application. Do not cover the treated area (s) with bandages or other dressings unless your doctor tells you otherwise (note that children's diapers can also function as occlusive bandages). Occlusive bandages can cause the active substance to be absorbed too intensely, increasing the possibility of side effects. For this reason, Synalar products should not be used on large areas of skin.

The administration may be carried out in:

  • Open cure: 2-3 times a day on the affected area and gently rubbing to its full disappearance.
  • Occlusive cure: 1 time a day, applying on the affected area, and covering it with a bandage with non-porous plastic. This type of treatment should not exceed 2 months.

Side effects & precautions

l Like all medicines, this medicine can cause side effects, although not all people suffer from them.

The occurrence of side effects is more likely with prolonged use or with excessive doses and with the application with occlusive bandages. The following sections details the known Synalar side effects and their frequency:

Rare side effects:

  • Skin atrophy
  • Telangiectasia (small, dilated blood vessels in the skin)
  • Stretch marks on the skin
  • Acne-like rashes
  • Perioral dermatitis (specific inflammation of the skin around the mouth)
  • Redness
  • Loss of skin coloration (hypopigmentation)
  • Contact dermatitis
  • Burning sensation

Very rare side effects

  • Adrenal suppression, which causes an alteration in the normal production of hormones by glands located next to the kidneys.

Side effects of unknown frequency:

  • Hypersensitivity, especially to lidocaine, with allergic reaction and anaphylactic reactions which could cause swelling under the skin, shortness of breath from narrowing of the bronchi, inflammation of the skin, involuntary contraction of the larynx, hives, itching, and shock
  • Dry skin
  • Itchiness
  • Skin maceration
  • Excessive hair growth (hypertrichosis)
  • Inflammation of hair follicles (folliculitis)
  • Secondary infection
  • Vesicles (miliaria)
  • Changes in stool color (black stool)

Synalar Precautions

Long-term use of topical corticosteroids can cause atrophy of the skin and subcutaneous tissue. When applied to the face, this can occur even in short-term treatments. The application of corticosteroids on large surfaces of the body can lead to a significant systemic absorption even if occlusive cure is not used. In children, the administration of topical corticosteroids should be limited to short periods of time and a minimum effective amount of the product. In the presence of an infection, appropriate therapy should be instituted. If there is no rapid improvement, treatment with SYNALAR Cream should be discontinued until controlled the infection. This preparation is not indicated for ophthalmic use.

Warnings

Athletes are informed that this medicine contains a component that may establish an analytical doping control result as positive.

Buying Synalar Cream online.

You can buy Synalar Cream Online online through one of the UK’s leading online pharmacies, Pharmacy Planet. It's easy and convenient. You will need to fill out a short assessment and the item will be delivered directly to your door. If you want to buy this skin inflammation treatment medication online, use Pharmacy Planet, a UK pharmacy you can trust.

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