Starlix

Starlix is ​​a medicine that lowers blood sugar (glycemia) and is taken by mouth (these medicines are also known as oral antidiabetics). It is used in people with Type 2 diabetes. (This type of diabetes is also called non-insulin-dependent diabetes mellitus). Insulin is a substance produced in an organ in the body called the pancreas that helps lower blood sugar levels, especially after meals. In Type 2 diabetes patients, the body cannot make insulin quickly enough after meals. Starlix stimulates the pancreas to make insulin more quickly. This helps control blood glucose after meals. Your doctor will prescribe Starlix together with another oral diabetic containing metformin.

Insulin is a substance produced in the body by the pancreas that helps lower blood sugar levels, especially after meals. If you have Type 2 diabetes, your body cannot make insulin fast enough after meals. Starlix stimulates the pancreas to make insulin more quickly, which helps keep blood sugar levels under control after meals. Starlix tablets begin to act soon after ingestion and are quickly eliminated from the body.

The active substance in Starlix, nateglinide, belongs to a group of medicines called oral antidiabetics. Starlix is ​​used to treat adult patients with Type 2 diabetes. Starlix tablet uses include being indicated to help control blood sugar levels. If despite a maximum tolerated dose of metformin it is not adequately controlled, your doctor will prescribe Starlix together with metformin.

Always take this medicine exactly as your doctor, pharmacist or nurse has told you. If in doubt, ask your doctor, pharmacist, or nurse again.

The starting Starlix tablet dose is ​​60 mg three times a day, administered before the three main meals. Your doctor can regularly check the amount of Starlix you are taking and can adjust the dose according to your needs. The maximum recommended dose is 180 mg three times a day, administered before the three main meals.

Take Starlix before meals. Its effect may be delayed if taken during or after meals.

Take Starlix before the three main meals, usually:

• 1 dose before breakfast
• 1 dose before a meal
• 1 dose before dinner

It is best to take it exactly before the main meal, but you can do it up to 30 minutes before.

Do not take it if you are not going to have a main meal. If you miss a meal, skip this dose of Starlix and wait until the next meal.

Swallow the tablets whole with a glass of water.

Even if you are taking medications for your diabetes, it is important that you follow the instructions recommended by your doctor regarding diet and/or exercise.

Like all medicines, this medicine can cause side effects, although not everybody gets them.

The adverse effects caused by Starlix are usually mild or moderate.

Common (may affect up to 1 in 10 patients):

These consist of symptoms of low blood sugar (hypoglycemia), usually mild. These comprise:

• sweat
• dizziness
• tremor
• weakness
• hungry
• feeling that your heart is beating fast
• fatigue
• feeling dizzy (nausea)

These symptoms may also be due to lack of food or too high doses of the antidiabetics you are taking. If you have symptoms of low blood sugar, eat or drink something that contains sugar.

Other adverse effects may include:

Common (may affect up to 1 in 10 people):

• abdominal pain, indigestion, diarrhea, nausea

Uncommon (may affect up to 1 in 100 patients):

• vomiting

Rare (may affect up to 1 in 1,000 patients):

• mild abnormalities of liver function tests, allergic reactions (hypersensitivity), such as rash and itching

Very rare (may affect up to 1 in 10,000 patients):

• a skin rash that manifests with blisters that affect the lips, eyes, and / or mouth, sometimes accompanied by headache, fever, and / or diarrhea

Warnings and precautions

Talk to your doctor, pharmacist, or nurse before taking Starlix.

Diabetes patients may develop symptoms associated with a drop in blood sugar (also called hypoglycemia). Oral antidiabetics, including Starlix, can also cause symptoms of hypoglycemia.

If you have low blood sugar, you may experience sweating, shaking (tremors), anxiety, difficulty concentrating, confusion, weakness, or fainting.

If this happens to you eat or drink something that contains sugar, and consult your doctor.

Some people are more likely to have symptoms of low blood sugar than others. Be careful:

• if you are over 65 years old.
• if you are malnourished.
• if you have another medical problem that may cause low blood sugar (eg reduced activity of the pituitary or adrenal gland).
• If any of these cases may apply to you, carefully monitor your blood sugar levels.

Watch carefully for signs of low blood sugar, especially:

• if you have performed more intense physical exercise than usual,
• if you have drunk alcohol.

Consult your doctor before taking Starlix.

• if you know you have liver problems.
• if you have a severe kidney problem.
• if you have problems with drug metabolism.
• if you are going to have an operation.
• if you have recently had a fever, accident or infection.
• You may need to adjust your treatment.

Children and adolescents

Starlix is ​​not recommended in children and adolescents (under 18 years of age) as its effect on this age group has not been studied.

Elderly people

People over 65 can take Starlix. These patients must take special care to avoid a drop in blood sugar.

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