Facebook Pixel
New Patients – Get 10% Off Your First Consultation with Code: NEW10 at Checkout

Nexium/Esomeprazole Tablets

Nexium tablets are used to treat conditions caused by gastric reflux, which is when the acidic content of the stomach returns to the esophagus (throat), because the sphincter (muscle at the junction of the esophagus and stomach) that normally acts as a valve in passing and prevents the return flow of stomach contents, does not work properly or is damaged. Gastroesophageal reflux disease (GERD), as this condition is known, causes symptoms such as heartburn and dyspepsia (indigestion and abdominal pain), and can damage the esophagus causing inflammation (esophagitis). Nexium tablets are also used to treat and prevent peptic ulcers in the stomach (gastric ulcers or damage to the stomach lining) and the duodenum (duodenal ulcers or damage to the lining of the upper intestine); and gastric ulcers caused by the use of non-steroidal anti-inflammatory drugs (NSAIDs); Also as a combination therapy to treat gastric ulcers caused by infection of the stomach with Helicobacter pylori bacteria, along with the use of antibiotics. Nexium tablets are also used to treat symptoms of acid-related dyspepsia that can be caused by eating foods high in fat or acids, or Zollinger-Ellison syndrome in which increased levels of gastrin hormone causes excessive production of gastric acid.
Consult
Select
Checkout
01
Select

the items you wish
to order

02
Order reviewed

by our qualified
prescriber

03
Delivered

to your door step

Your Selection

Please use the options provided to make your final selection.

prodName
Nexium/Esomeprazole Tablets
£14
Total
Consult
Select
Checkout
Please make a selection

Please note that whilst you are able to request the medicine strength and size required,
we will only be able to send on approval from our in house pharmacist.

Starts at £14.00
Price Comparison

Select your preferred options and see the best price

PackPrice (£)
Nexium20mg28 Tablets36.00
Nexium20mg56 Tablets58.00
Nexium40mg28 Tablets38.00
Nexium40mg56 Tablets62.00
Esomeprazole (Generic)20mg28 Tablets14.00
Esomeprazole (Generic)20mg56 Tablets16.00
Esomeprazole (Generic)40mg28 Tablets14.00
Esomeprazole (Generic)40mg56 Tablets17.00

It looks like you missed filling in questions from the last consultation.Click Here to submit your response.

  • No hidden fees

  • Secure checkout

  • UK Regulated online pharmacy

  • Trusted by over 100,000+ customers

Nexium Esomeprazole Tablets for Acid Reflux Relief

Nexium Esomeprazole tablets are used to reduce excess stomach acid and provide effective acid reflux relief, easing symptoms linked to gastro-oesophageal reflux disease, indigestion, and ongoing heartburn. Esomeprazole starts reducing acid from the first dose, but symptom relief is often noticeable after 2-3 days, with maximum benefit after several days (and sometimes weeks), depending on the condition. Many people buy Esomeprazole tablets when they need a reliable treatment that supports healing in the oesophagus and stomach while offering long-lasting comfort.

Esomeprazole is often chosen by people who experience frequent reflux or persistent discomfort despite over-the-counter remedies. As a PPI medication, it reduces acid production at its source, preventing irritation that can lead to inflammation or ulcer formation. You can order Esomeprazole tablets from Pharmacy Planet after completing a short online consultation reviewed by a UK prescriber.

For individuals seeking dependable symptom control, fewer flare-ups, and ongoing support for digestive health, Esomeprazole is a strong option to consider.

What are Nexium Esomeprazole Tablets?

Nexium contains the active ingredient Esomeprazole, a proton pump inhibitor used to reduce the amount of acid produced in the stomach. By targeting the proton pumps responsible for acid release, Esomeprazole tablets provide effective stomach acid reduction, supporting the healing of sensitive tissue and reducing inflammation.

People commonly buy Esomeprazole tablets to manage reflux symptoms, treat stomach and duodenal ulcers, or support recovery from conditions related to excess acid. Esomeprazole tablets may also be used with antibiotics when treating Helicobacter pylori infections, reducing the risk of ulcers returning.

Common Uses Include:

  • Persistent acid reflux and heartburn requiring structured heartburn treatment.
  • Acid-related indigestion.
  • Reflux oesophagitis caused by acid irritation.
  • Stomach or duodenal ulcers.
  • Ulcers linked to NSAID use.

Esomeprazole tablets are also prescribed for Zollinger-Ellison syndrome, a rare condition that causes excessive acid production.

How Do Esomeprazole Tablets Work?

Esomeprazole tablets work by blocking the enzyme responsible for releasing acid into the stomach. This enzyme, known as the proton pump, is located in the parietal cells of the stomach lining. When Esomeprazole tablets inhibit this pump, acid secretion decreases, supporting gastro-oesophageal reflux therapy and reducing irritation.

By lowering acid levels, Esomeprazole tablets can ease burning sensations, indigestion, and upper abdominal discomfort. Reduced acidity also allows damaged tissue in the oesophagus and stomach to heal more effectively. Because Esomeprazole tablets stop acid production rather than neutralising existing acid, they offer long-lasting and consistent gastric acid control.

Esomeprazole tablets usually start working within 2 to 3 hours, although the greatest benefit appears after several days of continuous use.

How to Use Esomeprazole Tablets?

Esomeprazole tablets are generally taken once daily. Swallow the tablet whole with water, ideally one hour before a meal. Avoid crushing or chewing the tablet.

Useful Tips for Best Results:

  • Take Esomeprazole tablets at the same time each day.
  • Complete the full course recommended by your prescriber.
  • Avoid other acid-reducing medicines unless advised.
  • Allow several days for steady symptom improvement.

Your prescriber may adjust your dosage depending on your condition, especially when treating ulcers or Zollinger-Ellison syndrome.

Who Can Use Esomeprazole Tablets?

Esomeprazole tablets may be suitable for:

  • Adults experiencing frequent reflux or heartburn.
  • Adults diagnosed with GERD or reflux oesophagitis.
  • People with stomach or duodenal ulcers.
  • Patients who need a prescription reflux medicine.
  • Individuals undergoing Helicobacter pylori eradication treatment.

Esomeprazole tablets are not suitable for:

  • Anyone allergic to Esomeprazole or similar medicines.
  • People with severe liver problems unless monitored.
  • Those with low magnesium levels unless corrected.
  • Individuals needing immediate relief, as Nexium's effects develop gradually.

If unsure, complete the Pharmacy Planet consultation for prescriber guidance.

Possible Side Effects of Esomeprazole Tablets

Esomeprazole tablets are generally well tolerated, although side effects can occur.

Common Side Effects:

  • Headache
  • Stomach pain
  • Diarrhoea or constipation
  • Gas or bloating
  • Nausea or vomiting

Less Common Side Effects:

  • Dizziness
  • Sleep disturbance
  • Dry mouth
  • Skin rash
  • Changes in liver function tests

Rare Side Effects:

  • Low sodium levels
  • Mood or behavioural changes
  • Vision changes
  • Joint or muscle pain
  • Fungal infections in the oesophagus

Very Rare Side Effects:

  • Severe allergic reactions
  • Severe skin reactions
  • Liver inflammation
  • Kidney problems

Seek medical help urgently if you experience swelling, breathing difficulty, severe rash, or yellowing of the skin or eyes.

Can Esomeprazole Tablets Be Used with Other Treatments?

Esomeprazole tablets can be used alongside certain medical treatments under supervision. It is commonly paired with antibiotics to treat Helicobacter pylori infection and may be used with NSAID therapy to protect the stomach lining.

However, interactions can occur. Always tell your prescriber about any medicines you are taking before you buy Esomeprazole tablets online. Tell your prescriber if you take clopidogrel; esomeprazole is usually avoided with it.

Consultation and Prescription Process at Pharmacy Planet

Here is how the consultation and prescription process works at Pharmacy Planet:

  1. Complete the online consultation and tell us about your symptoms and general health.
  2. A prescriber reviews your information to confirm whether Esomeprazole tablets are suitable.
  3. If approved, your Esomeprazole tablets are delivered discreetly to your door.
Nexium Esomeprazole Tablets

Nexium Esomeprazole tablets are used to reduce excess stomach acid and provide effective acid reflux relief, easing symptoms linked to gastro-oesophageal reflux disease, indigestion, and ongoing heartburn. Esomeprazole starts reducing acid from the first dose, but symptom relief is often noticeable after 2-3 days, with maximum benefit after several days (and sometimes weeks), depending on the condition. Many people buy Esomeprazole tablets when they need a reliable treatment that supports healing in the oesophagus and stomach while offering long-lasting comfort.

Esomeprazole is often chosen by people who experience frequent reflux or persistent discomfort despite over-the-counter remedies. As a PPI medication, it reduces acid production at its source, preventing irritation that can lead to inflammation or ulcer formation. You can order Esomeprazole tablets from Pharmacy Planet after completing a short online consultation reviewed by a UK prescriber.

For individuals seeking dependable symptom control, fewer flare-ups, and ongoing support for digestive health, Esomeprazole is a strong option to consider.

Nexium contains the active ingredient Esomeprazole, a proton pump inhibitor used to reduce the amount of acid produced in the stomach. By targeting the proton pumps responsible for acid release, Esomeprazole tablets provide effective stomach acid reduction, supporting the healing of sensitive tissue and reducing inflammation.

People commonly buy Esomeprazole tablets to manage reflux symptoms, treat stomach and duodenal ulcers, or support recovery from conditions related to excess acid. Esomeprazole tablets may also be used with antibiotics when treating Helicobacter pylori infections, reducing the risk of ulcers returning.

Common Uses Include:

  • Persistent acid reflux and heartburn requiring structured heartburn treatment.
  • Acid-related indigestion.
  • Reflux oesophagitis caused by acid irritation.
  • Stomach or duodenal ulcers.
  • Ulcers linked to NSAID use.

Esomeprazole tablets are also prescribed for Zollinger-Ellison syndrome, a rare condition that causes excessive acid production.

Esomeprazole tablets work by blocking the enzyme responsible for releasing acid into the stomach. This enzyme, known as the proton pump, is located in the parietal cells of the stomach lining. When Esomeprazole tablets inhibit this pump, acid secretion decreases, supporting gastro-oesophageal reflux therapy and reducing irritation.

By lowering acid levels, Esomeprazole tablets can ease burning sensations, indigestion, and upper abdominal discomfort. Reduced acidity also allows damaged tissue in the oesophagus and stomach to heal more effectively. Because Esomeprazole tablets stop acid production rather than neutralising existing acid, they offer long-lasting and consistent gastric acid control.

Esomeprazole tablets usually start working within 2 to 3 hours, although the greatest benefit appears after several days of continuous use.

Esomeprazole tablets are generally taken once daily. Swallow the tablet whole with water, ideally one hour before a meal. Avoid crushing or chewing the tablet.

Useful Tips for Best Results:

  • Take Esomeprazole tablets at the same time each day.
  • Complete the full course recommended by your prescriber.
  • Avoid other acid-reducing medicines unless advised.
  • Allow several days for steady symptom improvement.

Your prescriber may adjust your dosage depending on your condition, especially when treating ulcers or Zollinger-Ellison syndrome.

Esomeprazole tablets may be suitable for:

  • Adults experiencing frequent reflux or heartburn.
  • Adults diagnosed with GERD or reflux oesophagitis.
  • People with stomach or duodenal ulcers.
  • Patients who need a prescription reflux medicine.
  • Individuals undergoing Helicobacter pylori eradication treatment.

Esomeprazole tablets are not suitable for:

  • Anyone allergic to Esomeprazole or similar medicines.
  • People with severe liver problems unless monitored.
  • Those with low magnesium levels unless corrected.
  • Individuals needing immediate relief, as Nexium's effects develop gradually.

If unsure, complete the Pharmacy Planet consultation for prescriber guidance.

Esomeprazole tablets are generally well tolerated, although side effects can occur.

Common Side Effects:

  • Headache
  • Stomach pain
  • Diarrhoea or constipation
  • Gas or bloating
  • Nausea or vomiting

Less Common Side Effects:

  • Dizziness
  • Sleep disturbance
  • Dry mouth
  • Skin rash
  • Changes in liver function tests

Rare Side Effects:

  • Low sodium levels
  • Mood or behavioural changes
  • Vision changes
  • Joint or muscle pain
  • Fungal infections in the oesophagus

Very Rare Side Effects:

  • Severe allergic reactions
  • Severe skin reactions
  • Liver inflammation
  • Kidney problems

Seek medical help urgently if you experience swelling, breathing difficulty, severe rash, or yellowing of the skin or eyes.

Esomeprazole tablets can be used alongside certain medical treatments under supervision. It is commonly paired with antibiotics to treat Helicobacter pylori infection and may be used with NSAID therapy to protect the stomach lining.

However, interactions can occur. Always tell your prescriber about any medicines you are taking before you buy Esomeprazole tablets online. Tell your prescriber if you take clopidogrel; esomeprazole is usually avoided with it.

Here is how the consultation and prescription process works at Pharmacy Planet:

  1. Complete the online consultation and tell us about your symptoms and general health.
  2. A prescriber reviews your information to confirm whether Esomeprazole tablets are suitable.
  3. If approved, your Esomeprazole tablets are delivered discreetly to your door.
Frequently Asked Questions

Early relief usually appears within a few hours, with full benefits after several days.

Yes, Esomeprazole tablets can be used long-term under prescriber supervision.

You can, but you should not take them at the exact same time. Leave a gap of at least 1 to 2 hours to avoid affecting how Esomeprazole tablets work.

Alcohol can worsen reflux. Limit intake if it irritates your symptoms.

Yes, Esomeprazole tablets are often used to prevent or treat NSAID-related ulcers.

Yes, Esomeprazole tablets are frequently used as part of triple therapy.

Take it when you remember unless it is close to your next dose. Do not double the dose.

How it works
Start Consultation
Complete our online
clinical consultation

Answer a few questions on your health and your fitness goals.

Setup Coaching
Clinical
assessment

Our clinicians will review your clinical questionnaire to make sure treatment is right for you.

Ongoing Support
Welcome
aboard!

Once approved, you will access our wealth of experience and resources curated by our team and begin your clinical journey.

Start your journey with us

What our patients are saying

Need Help?

question mark
Do you have a question about weight loss treatment?

Start your weight loss journey heading in the right direction. Our team are here to help. Whether you’re unsure about which medicine is right for you or need help navigating the world of weight loss drugs, our team are on hand to help you make the right decision. We can put you in touch with one of our experienced weight loss clinicians so you can be sure you’re making the best decision with the most accurate information.

To get in touch, contact our Customer Service team on 0800 978 8956 or email [email protected].

Meet the team
Pharmacist Image

Authored on : April 8 2026

HARMINDER ‘HARMY’ KAUR

BSc(hons) Pharmacy

GPhC Number: 2061107

Pharmacist Image

Reviewed on : April 8 2026

GURDEV SEHMI

BSc Pharm, MRPharmS, Independent Prescriber, Superintendent Pharmacist, Clinical Lead

2050925