Mirabegron/Betmiga

Betmiga contains the active ingredient mirabegron. It is a medicine that relaxes the smooth muscle of the bladder (called a beta 3 adrenergic receptor agonist), which reduces the symptoms associated with overactive bladder.

The active ingredient in Betmiga, mirabegron, is a beta-3 adrenergic receptor agonist. It works by binding to beta-3 receptors found in the muscle cells of the bladder and activating them. Experimental studies have shown that once activated, the receptors beta-3s cause the bladder muscles to relax. It is estimated that this increases the bladder capacity and alters the way it contracts, which in turn results in a less number of contractions and therefore a decrease in involuntary urination.

Betmiga / Mirabegron is used to treat symptoms of overactive bladder in adults who:

• suddenly need to empty their bladder (called an emergency)
• they have to empty their bladder more often than normal (called an increase in urinary frequency)
• are unable to control themselves when their bladder is full (called urge incontinence)

Always use this medicine exactly as your doctor has told you. If in doubt, consult your doctor or pharmacist again.

The recommended dose is one 50 mg tablet orally once daily. If you have kidney or liver problems, your doctor may need to reduce the dose to one tablet of the whole. Do not crush or chew the tablet. Betmiga can be taken with or without food.

If you take more Betmiga than you should

If you take more tablets than prescribed, or if someone accidentally takes your tablets, immediately seek advice from your doctor, pharmacist, or hospital.

Overdose symptoms may include a pounding heartbeat, increased pulse rate, and increased blood pressure.

If you forget to take Betmiga

If you forget to take your medicine, take the missed dose as soon as you remember. If there are less than 6 hours left for the next scheduled dose, skip the dose and continue taking the medicine at the usual time.

Do not take a double dose to make up for a forgotten dose. If you miss several doses, consult your doctor and follow his recommendations.

Like all medicines, this medicine can cause side effects, although not everybody gets them.

More serious side effects may include an irregular heartbeat (atrial fibrillation). This is a rare side effect (may affect 1 in 100 people), but if this side effect appears, immediately stop taking the medicine and seek urgent medical advice. Check with your doctor if the headache appears, especially suddenly, migraine-like (palpitations) They can be signs of very high blood pressure. Other adverse effects include:

Common side effects (may affect up to 1 in 10 people)

• Increased heart rate (tachycardia)
• Infection of the structures that carry urine (urinary tract infections)
• nausea
• constipation
• Headache
• Diarrhea
• dizziness

Uncommon side effects (may affect up to 1 in 100 people)

• Bladder infection (cystitis)
• Feeling of the heartbeat (palpitations)
• Vaginal infection
• Indigestion (dyspepsia)
• stomach infection (gastritis)
• swelling of the joints
• Itching of the vulva or vagina (vulvovaginal itching)
• Increased blood pressure
• Increased liver enzymes (GGT, AST, and ALT)
• Itching, rash, or hives (hives, rash, macular rash, papular rash, itching)

Rare side effects (may affect up to 1 in 1,000 people)

• Swelling of the eyelids (eyelid edema)
• Swelling of the lips (lipedema)
• Swelling of the innermost layers of the skin caused by fluid accumulation, which can affect any part of the body including the face, tongue or throat and which can cause difficulty breathing (angioedema)
• Small purple spots on the skin (purple)
• Inflammation of small blood vessels that mainly affects the skin (leukocytoclastic vasculitis)
• Inability to completely empty the bladder (urinary retention)

Very rare side effects (may affect up to 1 in 10,000 people)

• Hypertensive crisis

Side effects of unknown frequency (frequency cannot be estimated from the available data)

• insomnia
• confusion

Betmiga may increase the chance that you will not be able to empty your bladder if you have a bladder outlet obstruction or if you are taking other medications to treat an overactive bladder. Tell your doctor immediately if you cannot empty your bladder.

Warnings

Talk to your doctor or pharmacist before taking Betmiga:

• if you have trouble emptying your bladder or have a weak stream of urine or if you take other medicines to treat an overactive bladder such as anticholinergic medicines.
• if you have kidney or liver problems. Your doctor may need to reduce the dose. Or it may tell you not to take Betmiga, especially if you are taking other medications such as itraconazole, ketoconazole (fungal infections), ritonavir (HIV / AIDS), or clarithromycin (bacterial infections). Tell your doctor about the medications you take.
• if you have a known abnormality on the ECG such as QT prolongation or are taking any medicine known to cause such abnormality such as quinidine, sotalol, procainamide, ibutilide, flecainide, dofetilide, and amiodarone.

You can buy Betmiga Tablets and Mirabegron Tablets online through one of the UK’s leading online pharmacies, Pharmacy Planet. It's easy and convenient. You will need to fill out a short assessment and the item will be delivered directly to your door. If you want to buy these Genito-Urinary Tablets online, use Pharmacy Planet, a UK pharmacy you can trust.