Isoket (Isosorbide dinitrate) is an organic nitrate of medium-long duration that is used in the treatment and prevention of angina
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Isoket (Isosorbide dinitrate) is an organic nitrate of medium-long duration that is used in the treatment and prevention of angina pectoris. Isosorbide dinitrate produces a direct relaxation of the vascular smooth muscle fiber, which is independent of the presence or absence of endothelium. The normal recommended dose is Isoket 1 tablet every 3-4 hours, ingested whole, without chewing, with a sufficient amount of liquid. On the other hand, the rapid absorption of isosorbide dinitrate sublingually means that this medicine can also be used in emergency situations, such as in acute angina attacks.
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Isoket (Isosorbide dinitrate) is an organic nitrate of medium-long duration heart medication that is used in the treatment and prevention of angina pectoris.
People also ask
What is Isoket?
Isoket (Isosorbide dinitrate) is an organic nitrate of medium-long duration heart medication that is used in the treatment and prevention of angina pectoris. It has also been used in the treatment of congestive heart failure in particular associated with hydralazine (an arteriolar vasodilator) and in the treatment of esophageal spasms. Each Isoket retard tablet just contains a compound called isosorbide dinitrate.
How does it work?
Isosorbide dinitrate produces a direct relaxation of the vascular smooth muscle fiber, which is independent of the presence or absence of endothelium. At this level, it facilitates the formation of oxide nitric (NO) that directly stimulates the activity of the soluble guanylate cyclase enzyme and increases the intracellular concentration of cGMP. A cGMP-dependent kinase is like this stimulated with the consequent alteration of the phosphorylation of various muscle proteins smooth. Eventually, this leads to dephosphorylation of the myosin light chain and a decrease of contractility.
What are the benefits of taking it?
The main function of the Isoket retard tablets serves is to carry out an easy prolongation of the revascularization process, in addition to avoiding or mitigating coronary spasm. This drug has a component that helps both peripheral arteries and veins to circulate, reducing pressure or preload, in other words, In addition, to helping with cardiac work. Isoket helps with acute left ventricular failure, It improves circulation, it functions as a treatment with acute myocardial infarction and with Severe angina pectoris.
How do I use it and its dosage?
The individual response of each patient requires adjusting the dose to their particular needs and the severity of the condition to be treated. Therefore, in some cases
Side effects & precautions
After prolonged use for the treatment of chronic conditions, tolerance may develop in patients, reducing their effectiveness. Nitrate tolerance mechanisms have been thoroughly investigated in the past 30 years and several hypotheses have been proposed. The following isosorbide dinitrate side effects include:
Serious allergic reactions (skin rash, hives, itching, shortness of breath, chest tightness, swelling of the mouth, face, lips, or tongue); Fainting; fast or slow heartbeat; nausea; new or worsening chest pain; vomiting
Inadequate biotransformation of isosorbide dinitrate to its active ingredient "NO" (nitric oxide, or a species related to "NO")
Neurohormonal activation
Buying Isoket online.
You can buy Isoket retard tablets online through one of the UK’s leading online pharmacies, Pharmacy Planet. It's easy and convenient. You will need to fill out a short assessment and the item will be delivered directly to your door. If you want to buy these Isosorbide Dinitrate tablets Online, use Pharmacy Planet, a UK pharmacy you can trust.
