The active ingredient in this Ezcema and psoriasis medication, Chlobetasone butyrate, is a corticosteroid whose anti-inflammatory action is moderately strong; thus, it is classified in Group 3 of the European Community list of corticosteroids for cutaneous use. It has a very wide margin of safety. Under conditions that predispose to maximum percutaneous absorption, Chlobetasone butyrate has a minimal effect on the hypothalamic-pituitary-adrenal cortical axis.
Clinical pharmacology studies carried out in animals and man have revealed the particularly high therapeutic index of this drug; In addition to good anti-inflammatory activity, a very low incidence of local and systemic side effects is observed, compared to other corticosteroids.
Follow these instructions unless your doctor has given you different directions. Remember to take your medicine. Your doctor will indicate the duration of your treatment with Trimovate cream. The usual dose is an application of a small amount of Trimovate cream on the affected area up to four times a day until there are an improvement and the application frequency. After washing your hands, apply the correct amount of cream to the affected areas of the skin until its disappearance. Unless used for treating hands, wash them again after applying the cream. Anyone who helps apply the cream should do the same or use disposable plastic gloves.
If in doubt, consult a doctor or pharmacist.
Using when pregnant
The application of topical steroids in pregnant animals can cause abnormalities in fetal development.
The relevance of these findings in humans has not been proven, however, topical steroids should not be used in pregnancy. Eg in large quantities or for long periods.
Like all medicines, Trimovate side effects can occur. At the application site, local allergic reactions such as redness, itching, rash, hives, local burning of the skin, and allergic contact dermatitis, which may resemble symptoms of the skin condition being treated.
When large areas of the body are treated with Trimoovate cream, there may be a deletion transient adrenal. Local atrophic changes, changes in color, amount of hair, and exacerbation of the symptoms. If any other adverse reaction not described above is observed, consult your doctor or pharmacist.
Warnings and precautions
Long-term continued topical corticosteroid therapy in children and infants should be avoided whenever possible, as adrenal suppression may occur even without occlusion. In infants, the diaper can act as an occlusive dressing and increase absorption.
If this antibacterial medication is applied to the eyelids, special care should be taken so that the preparation does not penetrate the eyes, as it could cause glaucoma.
As with all corticosteroids, prolonged application to the face is not recommended.
Appropriate antimicrobial therapy should be used each time inflammatory lesions that have become infected are treated. Any extension of infection requires the withdrawal of topical corticosteroid therapy and systemic administration of antimicrobial agents.
Precautions
In infants and children, long-term treatment with topical corticosteroids should be avoided whenever possible, since adrenal suppression can occur even without occlusion.
In infants, the diaper can act as an occlusive patch and increase absorption. As with all corticosteroids, its application for prolonged periods on the face is not recommended.
If applied to the eyelids, care must be taken that the preparation does not enter the eyes, as glaucoma may occur. Whenever an inflammatory lesion has become infected, appropriate antimicrobial therapy should be indicated.
Any extension of infection requires discontinuation of topical steroid therapy and systemic antimicrobial therapy should be instituted. The bacterial infection is stimulated by heat, and humidity conditions induced by the occlusive bandage, so the skin should be cleaned before applying a new bandage.
