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Seretide contains two active ingredients, salmeterol, and fluticasone propionate: Salmeterol is a long-lasting bronchodilator. Bronchodilators help keep the airways in the lungs open, making it easier for air to get in and out. The effects last at least 12 hours. Fluticasone propionate is a corticosteroid that decreases inflammation and irritation of the lungs. Your doctor has prescribed this medication to help prevent respiratory problems such as: Asthma. Chronic Obstructive Pulmonary Disease (COPD). Seretide Accuhaler, at a dose of 50/500 micrograms, reduces the number of exacerbations of COPD symptoms. You should use Seretide every day as your doctor has recommended. This will ensure that the medication works correctly to control your asthma or COPD. Seretide helps prevent shortness of breath and wheezing. However, Seretide should not be used to relieve a sudden attack of choking or wheezing. In such a case, you must use your fast-acting "rescue" medication, such as salbutamol. You should carry your fast-acting rescue medication with you at all times.
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PackPrice (£)
Seretide Accuhaler5001 Pack65.00
Seretide Accuhaler5002 Packs120.00
Seretide Accuhaler2501 Pack55.00
Seretide Accuhaler2502 Packs95.00
Seretide Accuhaler1001 Pack35.00
Seretide Accuhaler1002 Packs60.00
Seretide Evohaler502 Packs65.00
Seretide Evohaler1251 Pack55.00
Seretide Evohaler1252 Packs95.00
Seretide Evohaler501 Pack35.00
Seretide Evohaler2501 Pack80.00
Seretide Evohaler2502 Packs150.00

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Seretide is a prescription-only medicine (POM) that is used to treat asthma and chronic obstructive pulmonary disease, or COPD. This inhaler contains two ingredients: fluticasone propionate and salmeterol. Combined, these medicines help to reduce inflammation in the lungs and keep your airways dilated, allowing for a clearer passage for air to flow through. Seretide is a maintenance inhaler, meaning that it should be used daily to help prevent the frequency and severity of your asthma symptoms. Seretide is available in two formats: the Seretide Accuhaler, which is a dry powder formulation, and the Seretide Evohaler, which is a pressurised metered dose inhaler. This medication is suitable for individuals aged 4 and above, with dosages varying depending on your age and medical condition.

What is Seretide Accuhaler?

Seretide is an inhalation medication that dilates and protects the airways. Its active ingredients are salmeterol and fluticasone. Seretide reduces the sensitivity of the airways to stimuli and stops inflammation, in addition to facilitating breathing. Seretide is only sold by prescription.

How does Seretide Accuhaler work?

Seretide inhaler (CFC-free) contains fluticasone propionate, which is a corticosteroid and an anti-inflammatory medication that blocks the production of inflammatory chemicals released into the airways in response to the asthma trigger, such as allergens or airborne irritants. Inflammation is one of the underlying causes of asthma along with bronchospasm, which is constriction or narrowing of the bronchioles (small airways). The Seretide inhaler works directly on the walls of the airways to reduce inflammatory reactions in the airways, helping to prevent asthma symptoms caused by inflamed and inflamed airways such as wheezing, coughing, chest tightness and shortness of breath. It does not alleviate the bronchospasm that occurs during an asthma attack and you need a "soothing" medication to open your airways.

What are the benefits of using Seretide Accuhaler?

Seretide inhaler uses include being indicated as a treatment for respiratory diseases such as asthma and COPD (chronic obstructive pulmonary disease). The active substance salmeterol relaxes the muscles of the airways to facilitate breathing. The added fluticasone reduces the sensitivity of the airways to stimuli such as humidity, pets, or smoke, in addition to stopping the inflammation they cause. Seretide is used as a prevention, to prevent symptoms from appearing (chest tightness, cough, and shortness of breath); it is not effective in relieving acute respiratory crises.

How do I use Seretide Accuhaler and its dosage?

Using the accuhaler

  1. To open the Accuhaler, grasp the outer casing with one hand and place the thumb of the other hand in the space reserved for it. Push with your finger, away from you, as far as it will go. You will hear a click. This will open a small hole in the nozzle.
  2. Hold the device with the mouthpiece towards you. You can hold it with your right or left hand. Slide the lever away. You will hear a click. This will place the dose of medication in the mouthpiece.
  3. Every time the lever is pulled back, and alveolus opens and the powder is ready to be inhaled. Do not play with the lever because they open the alveoli and medicine is wasted.
  4. Keep the Accuhaler away from the mouth. Expel air as reasonably as possible. Do not breathe inside the Accuhaler.
  5. Place the mouthpiece on the lips; breath in progressively and intensely through the Accuhaler, not through the nose.
  6. Take the Accuhaler out of your mouth.
  7. Hold your breath for about 10 seconds or as long as possible.
  8. Expel air slowly.
  9. Then rinse your mouth with water and spit it out and/or brush your teeth. This can help you prevent mouth ulcers and hoarseness.
  10. To close the Accuhaler, slide the lever toward you as far as possible with your thumb. You will hear a click.

The lever will automatically return to its original position. The Accuhaler is now ready for reuse.

As with all inhalers, caregivers should ensure that children using Seretide Accuhaler correctly use the inhalation technique described above.

Using the inhaler

It is important to start breathing in as slowly as possible just before using your inhaler.

  1. It is recommended that you stand or sit upright while using the inhaler.
  2. Remove the mouthpiece guard. Check inside and outside that the nozzle is clean and that there are no foreign particles.
  3. Shake the inhaler 4 or 5 times to ensure the removal of any foreign particles and that the contents of the inhaler are mixed properly.
  4. Hold the inhaler upright with your thumb at the base of the inhaler, below the mouthpiece. Expel as much air as possible.
  5. Place the mouthpiece in the mouth between the teeth. Close your lips around the mouthpiece. Don't bite it.
  6. Take air through your mouth slowly and deeply. Right after you start to breathe in, press firmly on the top of the inhaler to release the medicine. Do this while continuing to breathe deeply and constantly.
  7. Hold your breath, remove the inhaler from your mouth by removing your finger from the top of the inhaler. Continue to hold your breath for a few seconds, as much as possible.
  8. Wait approximately half a minute between each application of the medicine and then repeat steps 3 to 7.

Then rinse your mouth with water and spit it out and / or brush your teeth. This will help you prevent ulcerations in your mouth and hoarseness.

After use, always replace the mouthpiece guard immediately to protect it from dust. When the mouthpiece guard is placed correctly it will click. If it does not click, turn the mouthpiece guard upside down and try again. Do not use excessive force.

Its dosage

Always use this medicine exactly as your doctor or pharmacist has told you. If in doubt, consult your doctor or pharmacist again.

Use Seretide every day, until your doctor tells you to stop. Do not take more than the recommended dose. If in doubt, ask your doctor or pharmacist.

Do not stop taking Seretide or reduce your dose without talking to your doctor first.

Seretide should be inhaled through the mouth into the lungs.

Adults and adolescents 12 years and older

Seretide 25/50 micrograms 2 applications twice a day

Seretide 25/125 micrograms 2 applications twice a day

Seretide 25/250 micrograms 2 applications twice a day

Children from 4 to 12 years old

Seretide 25/50 micrograms 2 applications twice a day

Seretide is not recommended for use in children younger than 4 years of age.

Your symptoms can become well controlled using Seretide twice a day. If so, your doctor may decide to decrease your dose to once a day. The dose may change to:

  • once at night if you have nighttime symptoms,
  • once in the morning if you have daytime symptoms.

What are the Side effects & precautions of Seretide Accuhaler?

Like all medicines, the Seretide Asthma Inhaler can cause side effects, although not everybody gets them. To reduce the occurrence of side effects, your doctor will prescribe the lowest dose of Seretide that controls your asthma or chronic obstructive pulmonary disease (COPD).

Allergic reactions: You may notice that your breathing suddenly worsens immediately after using Seretide. You may experience wheezing and coughing or shortness of breath. You may also notice itching, rash (hives), and swelling (usually of the face, lips, tongue, or throat). You may also suddenly feel like your heart is beating very fast, feel unconscious and dizzy (which can lead to collapse or loss of consciousness). If you experience any of these effects or appear suddenly after using Seretide, stop taking Seretide and contact your doctor immediately. Allergic reactions to Seretide are rare (affecting less than 1 in 100 people).

Pneumonia (infection of the lungs) in patients with COPD (frequent side effect)

Tell your doctor if you have any of the following symptoms while inhaling Seretide, they could be symptoms of a lung infection:

  • Fever or chills
  • Increased mucus production, change in mucus color
  • Increased cough or increased difficulty breathing

Other side effects are listed below:

Very common (may affect more than 1 in 10 people)

  • Headache, which usually improves with continued treatment.
  • An increase in the number of colds has been reported in patients with chronic obstructive pulmonary disease (COPD).

Common (may affect less than 1 in 10 people)

  • Candidiasis (itching, the appearance of creamy yellow ulcers) in the mouth and throat. Also sore tongue, hoarse voice, and sore throat. Rinsing your mouth with water and spitting it out and / or brushing your teeth immediately after each dose of medicine can help.
  • For the treatment of candidiasis, your doctor may prescribe antifungal medication (for the treatment of yeast infections).
  • Pain, inflammation in the joints, and muscle pain.
  • Muscle cramps.

The following side effects have been reported in patients with Chronic Obstructive Pulmonary Disease (COPD):

  • Cardinals and fractures.
  • Inflammation of the breasts (a feeling of tightness or congestion in the nose, cheeks, and behind the eyes, sometimes with throbbing pain).
  • Decreased blood potassium levels (you may feel irregular heartbeats, muscle weakness, cramps).

Uncommon (may affect less than 1 in 100 people)

  • Increased blood sugar (glucose) levels (hyperglycemia). If you have diabetes, it will be
  • It is necessary to control your blood sugar levels more frequently and adjust your usual diabetic treatment if necessary.
  • Cataracts (clouding of the lens of the eye).
  • Very fast heart rate (tachycardia).
  • Feeling tremors and fast or irregular heart rhythm (palpitations). These side effects are usually harmless and decrease with continued treatment.
  • Chest pain.
  • Feeling of concern (occurs mainly in children).
  • Sleep disorders.
  • Acne
  • Allergic rash on the skin.

Rare (may affect less than 1 in 1,000 people)

  • Shortness of breath (or wheezing) that gets worse right after using Seretide. If this happens, stop using Seretide. Use your quick-acting "rescue" inhaler to improve your breathing, and tell your doctor right away.
  • Seretide can increase the normal production of steroid hormones, particularly if you have been taking high doses for long periods of time. The effects include:
  • Delayed growth in children and adolescents.
  • Decreased bone mineral density.
  • Glaucoma
  • Weight gain.
  • Rounded face (shaped like a full moon) (Cushing's syndrome).

Your doctor will regularly monitor any of these side effects and will make sure that you are taking the lowest dose of Seretide to control your asthma.

Changes in behavior, such as hyperactivity and irritability (these effects occur mainly in children).

Irregular heartbeat or an abnormal heartbeat (arrhythmias). Talk to your doctor, but do not stop taking Seretide unless your doctor tells you to.

How to buy Seretide Accuhaler online in the UK?

You can buy the Seretide Inhaler online through one of the UK’s leading online pharmacies, Pharmacy Planet. It's easy and convenient. You will need to fill out a short assessment and the item will be delivered directly to your door. If you want to buy the Seretide All Strength Accuhaler online, use Pharmacy Planet, a UK pharmacy you can trust.

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Seretide is an inhalation medication that dilates and protects the airways. Its active ingredients are salmeterol and fluticasone. Seretide reduces the sensitivity of the airways to stimuli and stops inflammation, in addition to facilitating breathing. Seretide is only sold by prescription.

Seretide inhaler (CFC-free) contains fluticasone propionate, which is a corticosteroid and an anti-inflammatory medication that blocks the production of inflammatory chemicals released into the airways in response to the asthma trigger, such as allergens or airborne irritants. Inflammation is one of the underlying causes of asthma along with bronchospasm, which is constriction or narrowing of the bronchioles (small airways). The Seretide inhaler works directly on the walls of the airways to reduce inflammatory reactions in the airways, helping to prevent asthma symptoms caused by inflamed and inflamed airways such as wheezing, coughing, chest tightness and shortness of breath. It does not alleviate the bronchospasm that occurs during an asthma attack and you need a "soothing" medication to open your airways.

Seretide inhaler uses include being indicated as a treatment for respiratory diseases such as asthma and COPD (chronic obstructive pulmonary disease). The active substance salmeterol relaxes the muscles of the airways to facilitate breathing. The added fluticasone reduces the sensitivity of the airways to stimuli such as humidity, pets, or smoke, in addition to stopping the inflammation they cause. Seretide is used as a prevention, to prevent symptoms from appearing (chest tightness, cough, and shortness of breath); it is not effective in relieving acute respiratory crises.

Using the accuhaler

  1. To open the Accuhaler, grasp the outer casing with one hand and place the thumb of the other hand in the space reserved for it. Push with your finger, away from you, as far as it will go. You will hear a click. This will open a small hole in the nozzle.
  2. Hold the device with the mouthpiece towards you. You can hold it with your right or left hand. Slide the lever away. You will hear a click. This will place the dose of medication in the mouthpiece.
  3. Every time the lever is pulled back, and alveolus opens and the powder is ready to be inhaled. Do not play with the lever because they open the alveoli and medicine is wasted.
  4. Keep the Accuhaler away from the mouth. Expel air as reasonably as possible. Do not breathe inside the Accuhaler.
  5. Place the mouthpiece on the lips; breath in progressively and intensely through the Accuhaler, not through the nose.
  6. Take the Accuhaler out of your mouth.
  7. Hold your breath for about 10 seconds or as long as possible.
  8. Expel air slowly.
  9. Then rinse your mouth with water and spit it out and/or brush your teeth. This can help you prevent mouth ulcers and hoarseness.
  10. To close the Accuhaler, slide the lever toward you as far as possible with your thumb. You will hear a click.

The lever will automatically return to its original position. The Accuhaler is now ready for reuse.

As with all inhalers, caregivers should ensure that children using Seretide Accuhaler correctly use the inhalation technique described above.

Using the inhaler

It is important to start breathing in as slowly as possible just before using your inhaler.

  1. It is recommended that you stand or sit upright while using the inhaler.
  2. Remove the mouthpiece guard. Check inside and outside that the nozzle is clean and that there are no foreign particles.
  3. Shake the inhaler 4 or 5 times to ensure the removal of any foreign particles and that the contents of the inhaler are mixed properly.
  4. Hold the inhaler upright with your thumb at the base of the inhaler, below the mouthpiece. Expel as much air as possible.
  5. Place the mouthpiece in the mouth between the teeth. Close your lips around the mouthpiece. Don't bite it.
  6. Take air through your mouth slowly and deeply. Right after you start to breathe in, press firmly on the top of the inhaler to release the medicine. Do this while continuing to breathe deeply and constantly.
  7. Hold your breath, remove the inhaler from your mouth by removing your finger from the top of the inhaler. Continue to hold your breath for a few seconds, as much as possible.
  8. Wait approximately half a minute between each application of the medicine and then repeat steps 3 to 7.

Then rinse your mouth with water and spit it out and / or brush your teeth. This will help you prevent ulcerations in your mouth and hoarseness.

After use, always replace the mouthpiece guard immediately to protect it from dust. When the mouthpiece guard is placed correctly it will click. If it does not click, turn the mouthpiece guard upside down and try again. Do not use excessive force.

Its dosage

Always use this medicine exactly as your doctor or pharmacist has told you. If in doubt, consult your doctor or pharmacist again.

Use Seretide every day, until your doctor tells you to stop. Do not take more than the recommended dose. If in doubt, ask your doctor or pharmacist.

Do not stop taking Seretide or reduce your dose without talking to your doctor first.

Seretide should be inhaled through the mouth into the lungs.

Adults and adolescents 12 years and older

Seretide 25/50 micrograms 2 applications twice a day

Seretide 25/125 micrograms 2 applications twice a day

Seretide 25/250 micrograms 2 applications twice a day

Children from 4 to 12 years old

Seretide 25/50 micrograms 2 applications twice a day

Seretide is not recommended for use in children younger than 4 years of age.

Your symptoms can become well controlled using Seretide twice a day. If so, your doctor may decide to decrease your dose to once a day. The dose may change to:

  • once at night if you have nighttime symptoms,
  • once in the morning if you have daytime symptoms.

Like all medicines, the Seretide Asthma Inhaler can cause side effects, although not everybody gets them. To reduce the occurrence of side effects, your doctor will prescribe the lowest dose of Seretide that controls your asthma or chronic obstructive pulmonary disease (COPD).

Allergic reactions: You may notice that your breathing suddenly worsens immediately after using Seretide. You may experience wheezing and coughing or shortness of breath. You may also notice itching, rash (hives), and swelling (usually of the face, lips, tongue, or throat). You may also suddenly feel like your heart is beating very fast, feel unconscious and dizzy (which can lead to collapse or loss of consciousness). If you experience any of these effects or appear suddenly after using Seretide, stop taking Seretide and contact your doctor immediately. Allergic reactions to Seretide are rare (affecting less than 1 in 100 people).

Pneumonia (infection of the lungs) in patients with COPD (frequent side effect)

Tell your doctor if you have any of the following symptoms while inhaling Seretide, they could be symptoms of a lung infection:

  • Fever or chills
  • Increased mucus production, change in mucus color
  • Increased cough or increased difficulty breathing

Other side effects are listed below:

Very common (may affect more than 1 in 10 people)

  • Headache, which usually improves with continued treatment.
  • An increase in the number of colds has been reported in patients with chronic obstructive pulmonary disease (COPD).

Common (may affect less than 1 in 10 people)

  • Candidiasis (itching, the appearance of creamy yellow ulcers) in the mouth and throat. Also sore tongue, hoarse voice, and sore throat. Rinsing your mouth with water and spitting it out and / or brushing your teeth immediately after each dose of medicine can help.
  • For the treatment of candidiasis, your doctor may prescribe antifungal medication (for the treatment of yeast infections).
  • Pain, inflammation in the joints, and muscle pain.
  • Muscle cramps.

The following side effects have been reported in patients with Chronic Obstructive Pulmonary Disease (COPD):

  • Cardinals and fractures.
  • Inflammation of the breasts (a feeling of tightness or congestion in the nose, cheeks, and behind the eyes, sometimes with throbbing pain).
  • Decreased blood potassium levels (you may feel irregular heartbeats, muscle weakness, cramps).

Uncommon (may affect less than 1 in 100 people)

  • Increased blood sugar (glucose) levels (hyperglycemia). If you have diabetes, it will be
  • It is necessary to control your blood sugar levels more frequently and adjust your usual diabetic treatment if necessary.
  • Cataracts (clouding of the lens of the eye).
  • Very fast heart rate (tachycardia).
  • Feeling tremors and fast or irregular heart rhythm (palpitations). These side effects are usually harmless and decrease with continued treatment.
  • Chest pain.
  • Feeling of concern (occurs mainly in children).
  • Sleep disorders.
  • Acne
  • Allergic rash on the skin.

Rare (may affect less than 1 in 1,000 people)

  • Shortness of breath (or wheezing) that gets worse right after using Seretide. If this happens, stop using Seretide. Use your quick-acting "rescue" inhaler to improve your breathing, and tell your doctor right away.
  • Seretide can increase the normal production of steroid hormones, particularly if you have been taking high doses for long periods of time. The effects include:
  • Delayed growth in children and adolescents.
  • Decreased bone mineral density.
  • Glaucoma
  • Weight gain.
  • Rounded face (shaped like a full moon) (Cushing's syndrome).

Your doctor will regularly monitor any of these side effects and will make sure that you are taking the lowest dose of Seretide to control your asthma.

Changes in behavior, such as hyperactivity and irritability (these effects occur mainly in children).

Irregular heartbeat or an abnormal heartbeat (arrhythmias). Talk to your doctor, but do not stop taking Seretide unless your doctor tells you to.

You can buy the Seretide Inhaler online through one of the UK’s leading online pharmacies, Pharmacy Planet. It's easy and convenient. You will need to fill out a short assessment and the item will be delivered directly to your door. If you want to buy the Seretide All Strength Accuhaler online, use Pharmacy Planet, a UK pharmacy you can trust.

Frequently Asked Questions

No, the Seretide Inhaler is not a reliever inhaler and should not be used if you are experiencing a sudden asthma attack. The Seretide inhaler is a preventer inhaler, meaning that it has to be used over a long period to help control and manage symptoms over time. If you do find yourself having severe asthma symptoms or asthma attacks, make sure that you always carry a reliever inhaler such as Ventolin for these emergencies.

Though Seretide does not provide instant relief, it can take a couple of days to improve breathing. Overall, the Seretide inhaler can help to improve symptoms over time and should be used consistently. Some patients have noticed that after two weeks, their asthma symptom management and flare-ups have improved. Make sure to use this medicine daily as prescribed by your clinician for optimal asthma and COPD management.

If you are pregnant or planning a pregnancy, make sure to speak to your healthcare professional before using Seretide. There are no confirmed risks; however, this medicine should only be used if the benefits outweigh the risks of having this medicine. For mothers who are currently breastfeeding, ensure you also consult your healthcare professional for safe administration.

If you miss a dose of your Seretide Inhaler, take it as soon as you remember. However, if it’s close to your next dose, do not take two doses. Simply continue with your regular routine and try to avoid missing any future doses.

Like all medicines, Seretide can interact with other medications. You should keep a close eye on any unusual signs and symptoms if you use any of the following medicines:

  • Beta Blockers (used for hypertension or heart conditions).
  • Antifungal medicines.
  • HIV medicines.

Make sure that if you are on these or any other medicines, you inform your healthcare professional or pharmacist.

Store your inhaler at room temperature (below 30°C). Ensure that the storage area is dry and not exposed to direct sunlight or heat. Do not puncture the canister or expose it to high temperatures, as the pressurised gas inside could be hazardous. Always keep this medicine out of reach of children and pets.

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Authored By

HARMINDER ‘HARMY’ KAUR

BSc(hons) Pharmacy

GPhC Number: 2061107

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BSc Pharm, MRPharmS, Independent Prescriber, Superintendent Pharmacist, Clinical Lead

GPhC Number: 2050925