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Sereflo Inhalers

The Sereflo inhaler contains two active ingredients, salmeterol, and fluticasone propionate: Salmeterol is a long-lasting bronchodilator. Bronchodilators help keep the airways in the lungs open, making it easier for air to get in and out. The effects last at least 12 hours. Fluticasone propionate is a corticosteroid that decreases inflammation and irritation of the lungs. This medicine is also used to prevent exacerbations or worsening of chronic obstructive pulmonary disease (COPD; COPD) associated with chronic bronchitis or emphysema. However, Sereflo should not be used to relieve a sudden attack of choking or wheezing. In such a case, you must use your fast-acting "rescue" medication, such as salbutamol.
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Sereflo Inhalers
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Please note that whilst you are able to request the medicine strength and size required,
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Starts at £32.00
Price Comparison

Select your preferred options and see the best price

PackPrice (£)
-25/125mcg1 Inhaler32.00
-25/125mcg2 Inhalers59.00
-25/125mcg3 Inhalers85.00
-25/250mcg1 Inhaler43.00
-25/250mcg2 Inhalers79.00
-25/250mcg3 Inhalers112.00

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Sereflo Inhalers for Ongoing Asthma and COPD Symptom Control

Sereflo contains both medicines in one inhaler, ensuring the long-acting bronchodilator is always used alongside an inhaled corticosteroid. Sereflo inhalers are prescribed for people who need steady, long-term control of asthma or chronic obstructive pulmonary disease (COPD). They are combination inhalers containing salmeterol/fluticasone, bringing together an inhaled corticosteroid and a long-acting bronchodilator in one treatment.

Sereflo inhalers are used as part of daily respiratory care to calm airway inflammation, keep the airways open, and reduce the chance of flare-ups. They are not used for sudden breathing attacks but for ongoing support that keeps breathing more predictable over time. If approved after an online consultation, you can order Sereflo inhalers from Pharmacy Planet.

What Are Sereflo Inhalers?

Sereflo inhalers are prescription inhalers used for chronic asthma treatment and COPD management in adults. Each inhaler contains two medicines that work together: salmeterol, a long-acting bronchodilator that keeps the airways open for around 12 hours, and fluticasone propionate, a corticosteroid that reduces swelling and irritation inside the airways.

This combination is usually prescribed when a steroid inhaler on its own does not give enough symptom control, or when breathing symptoms return between doses of other treatments.

How Do Sereflo Inhalers Work?

Breathing problems in asthma and COPD often come from two linked issues: narrowed airways and ongoing inflammation. Sereflo inhalers address both.

  • Fluticasone Reduces Airway Inflammation — This settles irritated airways and lowers sensitivity to triggers such as allergens, exercise, or cold air.
  • Salmeterol Keeps the Airways Open — Relaxed airway muscles make breathing feel easier and more consistent through the day and night.
  • Combined Treatment Supports Stable Breathing — Regular use reduces wheezing, chest tightness, and breathlessness over time.

Since this is a preventer treatment, Sereflo inhalers must be used every day, even when breathing feels well controlled.

How to Use Sereflo Inhalers

Sereflo inhalers are prescribed for adults with asthma or COPD following medical assessment.

Dosage Guidance:

  • The usual dose is two puffs, twice daily, taken in the morning and evening.
  • Available in 25/125 micrograms and 25/250 micrograms strengths.
  • Do not stop using Sereflo or change your dose without medical advice, even if symptoms improve.

Steps for Using the Sereflo Inhaler:

  1. Sit or stand upright.
  2. Remove the mouthpiece cover and check it is clean.
  3. Shake the inhaler 4–5 times.
  4. Breathe out gently, away from the inhaler.
  5. Place the mouthpiece between your teeth and seal your lips.
  6. Breathe in slowly and press the canister at the same time.
  7. Continue breathing in, then hold your breath briefly.
  8. Breathe out gently.
  9. Wait around 30 seconds before the next puff.
  10. Rinse your mouth with water or brush your teeth after use.

Who Can Use Sereflo Inhalers?

Sereflo inhalers may be suitable for people who:

  • Have asthma that is not fully controlled with a preventer inhaler alone.
  • Need a combination inhaler for ongoing symptom control.
  • Have COPD with persistent breathlessness or frequent flare-ups.
  • Experience nighttime symptoms or regular wheezing.
  • Need long-term airway management rather than short-term relief.

Sereflo inhalers may not be suitable for people who:

  • Need immediate relief during sudden asthma attacks.
  • Are allergic to fluticasone, salmeterol, or other inhaler ingredients.
  • Have certain heart conditions without medical review.

A UK prescriber will review your medical history during the online consultation at Pharmacy Planet to confirm suitability.

Possible Side Effects of Sereflo Inhalers

Like all medicines, Sereflo inhalers can cause side effects, although not everyone gets them.

Common Side Effects:

  • Headache
  • Oral thrush in the mouth or throat
  • Muscle cramps or joint discomfort
  • Increased colds in people with COPD

Serious Side Effects:

  • Sudden worsening of breathing after inhalation
  • Fast or irregular heartbeat
  • Swelling, rash, or signs of an allergic reaction
  • Feeling faint or light-headed

If breathing worsens suddenly or serious side effects occur, stop using the inhaler and seek medical advice straight away.

Why Do People Choose Sereflo Inhalers?

Sereflo inhalers are often chosen because they combine inflammation control and airway opening in one inhaler. Common reasons include:

  • Reduce daily breathlessness and wheezing.
  • Support steadier breathing across day and night.
  • Reduce reliance on multiple inhalers.
  • Fit into long-term asthma relief and COPD management plans.

For many people, this balanced approach supports better breathing control and everyday confidence.

Consultation and Order Process at Pharmacy Planet

Getting Sereflo inhalers from Pharmacy Planet is simple:

  1. Complete the online consultation and share details about your asthma or COPD symptoms and general health.
  2. A UK prescriber assesses whether Sereflo inhalers are suitable for you.
  3. If approved, your inhaler is dispensed and delivered discreetly to your address.
Sereflo Inhaler

Sereflo inhalers are prescribed for people who need steady, long-term control of asthma or COPD. They are combination inhalers containing salmeterol/fluticasone, bringing together an inhaled corticosteroid and a long-acting bronchodilator in one treatment.

Sereflo inhalers are used for ongoing support that keeps breathing more predictable over time, not for sudden attacks. If approved after an online consultation, you can order Sereflo inhalers from Pharmacy Planet.

Sereflo inhalers are prescription combination inhalers for adults. They contain salmeterol (long-acting bronchodilator, keeps airways open for ~12 hours) and fluticasone propionate (corticosteroid, reduces airway inflammation).

They are usually prescribed when a steroid inhaler alone does not provide enough control.

Sereflo inhalers address both narrowed airways and ongoing inflammation.

  • Fluticasone Reduces Airway Inflammation — Settles irritated airways and lowers sensitivity to triggers.
  • Salmeterol Keeps the Airways Open — Relaxed airway muscles make breathing feel easier day and night.
  • Combined Treatment Supports Stable Breathing — Regular use reduces wheezing, chest tightness, and breathlessness.

Prescribed for adults with asthma or COPD. Usual dose: two puffs twice daily (morning and evening). Available in 25/125 mcg and 25/250 mcg strengths.

Steps for Use:

  1. Sit or stand upright and shake the inhaler 4–5 times.
  2. Breathe out gently, away from the inhaler.
  3. Place the mouthpiece between your teeth and seal your lips.
  4. Breathe in slowly and press the canister at the same time.
  5. Hold your breath briefly, then breathe out gently.
  6. Wait 30 seconds before the next puff.
  7. Rinse your mouth with water after use.

Sereflo inhalers may be suitable for people who:

  • Have asthma not fully controlled with a preventer inhaler alone.
  • Have COPD with persistent breathlessness or frequent flare-ups.
  • Experience nighttime symptoms or regular wheezing.
  • Need long-term airway management rather than short-term relief.

Sereflo inhalers may not be suitable for people who:

  • Need immediate relief during sudden asthma attacks.
  • Are allergic to fluticasone, salmeterol, or other inhaler ingredients.
  • Have certain heart conditions without medical review.

Like all medicines, Sereflo inhalers can cause side effects.

Common Side Effects:

  • Headache
  • Oral thrush in the mouth or throat
  • Muscle cramps or joint discomfort
  • Increased colds in people with COPD

Serious Side Effects:

  • Sudden worsening of breathing after inhalation
  • Fast or irregular heartbeat
  • Swelling, rash, or signs of an allergic reaction

Seek medical advice straight away if serious side effects occur.

Sereflo inhalers are often chosen because they combine inflammation control and airway opening in one inhaler. Common reasons include:

  • Reduce daily breathlessness and wheezing.
  • Support steadier breathing across day and night.
  • Reduce reliance on multiple inhalers.
  • Fit into long-term asthma and COPD management plans.

Getting Sereflo inhalers from Pharmacy Planet is simple:

  1. Complete the online consultation and share details about your asthma or COPD symptoms and general health.
  2. A UK prescriber assesses whether Sereflo inhalers are suitable for you.
  3. If approved, your inhaler is dispensed and delivered discreetly to your address.
Frequently Asked Questions

Sereflo is a preventer inhaler. It is used every day to control asthma or COPD over time. It does not work as a quick-relief inhaler for sudden breathing problems.

The Sereflo inhaler keeps breathing stable in the background, but it does not act fast enough for sudden symptoms. A reliever inhaler is still needed for quick relief during flare-ups.

Some people notice breathing feels easier within a few days. Full benefit builds gradually over a few weeks of regular daily use.

Yes. Sereflo is often prescribed when asthma symptoms are triggered by allergens such as pollen, dust, or pets. It reduces airway inflammation that develops after allergen exposure.

Rinsing your mouth removes leftover steroid medicine from the throat. This reduces the risk of soreness, hoarseness, and oral thrush.

If you stop Sereflo, airway inflammation can return and symptoms may worsen. You should always speak to your prescriber before stopping or changing your dose.

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Review By

HARMINDER ‘HARMY’ KAUR

Last Updated On : Mar 13 2026

BSc(hons) Pharmacy

GPhC Number: 2061107

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Last Reviewed On : Mar 23 2026

BSc Pharm, MRPharmS, Independent Prescriber, Superintendent Pharmacist, Clinical Lead

GPhC Number: 2050925