Sereflo Inhalers

The Sereflo inhaler is a combined steroid and bronchodilator medicine that is used to prevent an asthma attack. This medicine is also used to prevent exacerbations or worsening of chronic obstructive pulmonary disease (COPD; COPD) associated with chronic bronchitis or emphysema.

The Sereflo inhaler contains salmeterol and fluticasone propionate that have different mechanisms of action. The respective mechanisms of action of both drugs are outlined below:

Salmeterol:

Salmeterol is a long-acting selective agonist (12 hours) of β2 adrenergic receptors, with a long side chain that binds to the external receptor area.

Salmeterol results in longer bronchodilation, lasting at least 12 hours, compared to the recommended doses for conventional short-acting β2 adrenergic receptor agonists.

Fluticasone propionate:

Fluticasone propionate administered by inhalation at the recommended doses has a glucocorticoid anti-inflammatory action at the pulmonary level that results in a reduction of symptoms and asthma exacerbations, with fewer adverse reactions than when corticosteroids are administered systemically.

Always use this asthma treatment medication exactly as your doctor or pharmacist has told you. If in doubt, consult your doctor or pharmacist again.

Using the inhaler.

1. It is important to start breathing in as slowly as possible just before using your inhaler.
2.  It is recommended that you stand or sit upright while using the inhaler.
3. Remove the mouthpiece guard. Check inside and outside that the nozzle is clean and that there are no foreign particles.
4. Shake the inhaler 4 or 5 times to ensure the removal of any foreign particles and that the contents of the inhaler are mixed properly.
5. Hold the inhaler upright with your thumb at the base of the inhaler, below the mouthpiece. Expel as much air as possible.
6. Place the mouthpiece in the mouth between the teeth. Close your lips around the mouthpiece. Don't bite it.
7. Take air through your mouth slowly and deeply. Right after you start to breathe in, press firmly on the top of the inhaler to release the medicine. Do this while continuing to breathe deeply and constantly.
8. Hold your breath, remove the inhaler from your mouth by removing your finger from the top of the inhaler. Continue holding your breath for a few seconds, as much as you can.
9. Wait approximately half a minute between each application of the medicine and then repeat steps 3 to 7.
10. Then rinse your mouth with water and spit it out and / or brush your teeth. This will help you prevent ulcerations in your mouth and hoarseness.
11. After use, always replace the mouthpiece guard immediately to protect it from dust. When the mouthpiece guard is placed correctly it will click. If it does not click, turn the mouthpiece guard upside down and try again. Do not use excessive force.

Use Sereflo every day, until your doctor tells you to stop. Do not take more than the recommended dose. If in doubt, ask your doctor or pharmacist. Do not stop taking sereflo or reduce your dose without first talking to your doctor. Sereflo must be inhaled through the mouth into the lungs.

Adults and adolescents 12 years and older

Sereflo 25/125 micrograms 2 applications twice a day

Children from 4 to 12 years old

Sereflo is not recommended for use in children younger than 4 years of age.

Your symptoms can be well controlled using Sereflo twice a day. If so, your doctor may decide to decrease your dose to once a day. The dose may change to:

• once at night if you have nighttime symptoms,
• once in the morning if you have daytime symptoms

Like all medicines, this medicine can cause side effects, although not everybody gets them. To reduce the occurrence of side effects, your doctor will prescribe the lowest dose of Sereflo to control your asthma.

Allergic reactions: You may notice that your breathing suddenly worsens immediately after using Sereflo. You may experience wheezing and coughing or shortness of breath. You may also notice itching, rash (hives), and swelling (usually of the face, lips, tongue, or throat). You may also suddenly feel like your heart is beating very fast, feel unconscious, and dizzy (which can lead to collapse or loss of consciousness). If you experience any of these effects or appear suddenly after using Sereflo, stop taking Sereflo and contact your doctor immediately. Allergic reactions to Sereflo are rare (affect less than 1 in 100 people).

Other side effects are listed below:

Very common (may affect more than 1 in 10 people)

• A headache that usually improves with continued treatment.
• An increase in the number of colds has been reported in patients with COPD.

Common (may affect less than 1 in 10 people)

• Canker sores (itching, creamy yellow ulcers) in the mouth and throat. Also sore tongue, hoarse voice, and sore throat. Rinsing your mouth with water and spitting it out and / or brushing your teeth immediately after each dose of medicine can help. Your doctor may prescribe antifungal medication to treat canker sores.
• Pain, inflammation in the joints, and muscle pain.
• Muscle cramps.

Uncommon (may affect less than 1 in 100 people)

• Increased blood sugar (glucose) levels (hyperglycemia). If you have diabetes, you will need to monitor your blood sugar levels more frequently and adjust your usual diabetic treatment if necessary.
• Cataracts (clouding of the lens of the eye).
• Very fast heart rate (tachycardia).
• Feeling tremors and fast or irregular heart rhythm (palpitations). These side effects are usually harmless and decrease with continued treatment.
• Chest pain.
• Feeling of concern (occurs mainly in children).
• Sleep disorders.
• Acne
• Allergic rash on the skin.

Rare (may affect less than 1 in 1,000 people)

• Breathing difficulties or wheezing that get worse right after using Sereflo. If this happens, stop using Sereflo. Use your quick-acting "rescue" inhaler to improve your breathing, and tell your doctor right away.
• Sereflo can increase the normal production of steroid hormones, particularly if you have been taking high doses for long periods of time. The effects include:
• Delayed growth in children and adolescents.
• Decreased bone mineral density.
• Glaucoma
• Weight gain.
• Rounded face (shaped like a full moon) (Cushing's syndrome).
• Your doctor will regularly monitor any of these side effects and will make sure that you are taking the lowest dose of Sereflo to control your asthma.
• Changes in behavior, such as hyperactivity and irritability (these effects mainly occur in children).
• Irregular heartbeat or an abnormal heartbeat (arrhythmias). Talk to your doctor, but don't stop taking Sereflo unless your doctor tells you to.

You can buy the Sereflo inhaler online through one of the UK’s leading online pharmacies, Pharmacy Planet. It's easy and convenient. You will need to fill out a short assessment and the item will be delivered directly to your door. If you want to buy this Asthma Inhaler online, use Pharmacy Planet, a UK pharmacy you can trust.