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Rectogesic GTN Ointment

Rectogesic is an analgesic ointment that is suitable for anal use. The active substance is glyceryl trinitrate - a vasodilator. Rectogesic ensures that the bloodstream in the anus widens so that more blood can flow into the tissue. This relieves complaints such as pain and a feeling of oppression. This medicine can only be obtained with a doctor's prescription. Doctors prescribe Rectogesic for anal fissures. These are cracks in the skin of the anal canal caused by constipation when the stool is very dry and hard. An anal fissure causes enormous pain in the anus, especially during and after bowel movements. Sometimes you can find bright red blood in the stool itself. Rectogesic relieves pain and improves blood flow to the anus, which means the cracks heal faster.

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Rectogesic GTN Ointment
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Please note that whilst you are able to request the medicine strength and size required,
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Starts at £92.00
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PackPrice (£)
-0.00430g x 1 Tube92.00
-0.00430g x 2 Tubes173.00
-0.00430g x 3 Tubes253.00

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Rectogesic GTN Ointment for Anal Fissures and Haemorrhoid Pain Relief

Rectogesic GTN ointment is a topical nitrate ointment used in adults to treat pain and discomfort from chronic anal fissures and related anorectal symptoms. The active ingredient used in Rectogesic GTN ointment is glyceryl trinitrate (GTN), a vasodilator that relaxes the internal anal sphincter and increases blood flow to the affected tissue.

This action can reduce pain during and after bowel movements and support the healing process of painful tears in the anoderm. Rectogesic GTN ointment is a prescription-only medicine in the UK.

You can buy Rectogesic GTN ointment online from Pharmacy Planet after a short and free online consultation with one of our UK prescribers. If you are seeking targeted pain reduction and improved healing with a topical GTN ointment, Rectogesic is an option worth considering.

What is Rectogesic GTN Ointment?

Rectogesic GTN ointment is a rectal ointment containing glyceryl trinitrate (GTN) 4 mg/g. Glyceryl trinitrate belongs to a class of medicines known as organic nitrates. Unlike simple moisturising or anaesthetic creams, this ointment directly targets muscle tension and blood flow in the anal area to address the root cause of pain and delayed healing in chronic fissures.

Rectogesic is prescribed for adults with chronic anal fissures that have not healed with initial conservative measures like high-fibre diets, laxatives or sitz baths.

Common uses of Rectogesic GTN ointment include:

  • Pain reduction from chronic anal fissures.
  • Relief from rectal muscle spasm that contributes to pile discomfort and fissure pain.
  • Improved blood flow to the anorectal tissues to support healing.

How Rectogesic GTN Ointment Works?

Rectogesic GTN Ointment targets the underlying muscle tension and reduced blood flow that drive ongoing anal fissure pain.

  • Glyceryl trinitrate in Rectogesic releases nitric oxide when applied to the anal canal.
  • Nitric oxide relaxes the smooth muscle of the internal anal sphincter.
  • Relaxation of this muscle reduces anal pressure and increases blood flow in the area.
  • Increased circulation eases pain and can help the skin of the fissure to heal more efficiently.

This targeted action makes Rectogesic more than a simple pain relief ointment. It addresses muscle spasm and impaired blood supply, which are key factors in chronic fissure discomfort.

How to Use Rectogesic GTN Ointment?

Rectogesic GTN ointment should be used exactly as directed by your UK prescriber. Always follow their instructions and the patient information leaflet supplied with the medicine.

Typical Application Steps:

  • Wash and dry your hands.
  • Cover the tip of a finger with a finger cot, cling film, or disposable glove.
  • Express a 2.5 cm strip of ointment onto your finger.
  • Gently insert the finger into the anal canal up to the first joint and apply the ointment around the inside of the anus.
  • Apply Rectogesic GTN ointment every 12 hours or as prescribed.
  • Continue treatment for up to 8 weeks or until pain subsides.
  • Wash hands thoroughly after each use.

Do not exceed the recommended dose, and do not use more frequently than prescribed. If symptoms persist beyond the treatment period, complete a follow-up consultation so our prescriber can reassess your condition.

Who Can Use Rectogesic GTN Ointment?

Rectogesic GTN ointment may be suitable for adults who:

  • Have chronic anal fissure pain that has not resolved with initial self-care.
  • Are experiencing significant rectal spasm contributing to pain and delayed healing.
  • Need a topical nitrate ointment to target both pain and blood supply issues.

Rectogesic GTN ointment is not suitable for:

  • Anyone under 18 years of age.
  • People allergic to glyceryl trinitrate or similar nitrates.
  • Those with low blood pressure or heart conditions worsened by nitrates unless closely monitored.
  • Anyone using other nitrate medications or PDE5 inhibitors like sildenafil products concurrently.
  • Patients who are pregnant or breastfeeding unless specifically advised by a prescriber.

Completing the online consultation helps our prescriber decide whether Rectogesic GTN ointment is appropriate based on your health and symptoms.

Possible Side Effects of Rectogesic GTN Ointment

Rectogesic can cause side effects in some people, while others may not notice any unwanted effects at all.

Very Common Side Effects (Affect More Than 1 in 10 People):

  • Headache that may be severe initially and often reduces over time (this is frequently related to GTN absorption).

Common Side Effects (Up to 1 in 10 People):

  • Light-headedness.
  • Feeling sick.

Less Common Side Effects (Up to 1 in 100 People):

  • Local irritation, burning or itching around the anus.
  • Increased heart rate or palpitations.

Rare Side Effects:

  • Significant drop in blood pressure.
  • Severe allergic reactions.

If you notice anything serious or unusual after using Rectogesic GTN ointment, stop use and complete a follow-up consultation so our prescriber can advise you based on your condition.

Why Order Rectogesic GTN Ointment from Pharmacy Planet?

Rectogesic GTN ointment is a targeted topical treatment for chronic anal fissure pain and associated muscle spasm. Its nitrate action not only reduces pain but also improves local blood flow, which can support quicker healing when conservative measures alone are not enough.

With Pharmacy Planet you get:

  • A UK prescriber review to confirm suitability.
  • Convenient online consultation at no extra cost before purchase.
  • Fast and discreet UK delivery to your door.

If you are looking for a prescription nitrate ointment that targets pain, improves local circulation and supports fissure healing, Rectogesic GTN ointment is a practical option worth discussing with your prescriber.

Consultation and Prescription Process at Pharmacy Planet

At Pharmacy Planet, getting access to Rectogesic GTN ointment online is straightforward and designed to ensure the treatment is appropriate for you.

  1. Complete the online consultation and tell us about your symptoms, pain levels and medical history.
  2. Our prescriber reviews your responses to decide if Rectogesic GTN ointment is suitable.
  3. If approved, your prescription is dispensed and delivered discreetly to your address.
Rectogesic GTN Ointment

Rectogesic GTN ointment is a topical nitrate ointment used in adults to treat pain and discomfort from chronic anal fissures and related anorectal symptoms. The active ingredient used in Rectogesic GTN ointment is glyceryl trinitrate (GTN), a vasodilator that relaxes the internal anal sphincter and increases blood flow to the affected tissue.

This action can reduce pain during and after bowel movements and support the healing process of painful tears in the anoderm. Rectogesic GTN ointment is a prescription-only medicine in the UK.

You can buy Rectogesic GTN ointment online from Pharmacy Planet after a short and free online consultation with one of our UK prescribers. If you are seeking targeted pain reduction and improved healing with a topical GTN ointment, Rectogesic is an option worth considering.

Rectogesic GTN ointment is a rectal ointment containing glyceryl trinitrate (GTN) 4 mg/g. Glyceryl trinitrate belongs to a class of medicines known as organic nitrates. Unlike simple moisturising or anaesthetic creams, this ointment directly targets muscle tension and blood flow in the anal area to address the root cause of pain and delayed healing in chronic fissures.

Rectogesic is prescribed for adults with chronic anal fissures that have not healed with initial conservative measures like high-fibre diets, laxatives or sitz baths.

Common uses of Rectogesic GTN ointment include:

  • Pain reduction from chronic anal fissures.
  • Relief from rectal muscle spasm that contributes to pile discomfort and fissure pain.
  • Improved blood flow to the anorectal tissues to support healing.

Rectogesic GTN Ointment targets the underlying muscle tension and reduced blood flow that drive ongoing anal fissure pain.

  • Glyceryl trinitrate in Rectogesic releases nitric oxide when applied to the anal canal.
  • Nitric oxide relaxes the smooth muscle of the internal anal sphincter.
  • Relaxation of this muscle reduces anal pressure and increases blood flow in the area.
  • Increased circulation eases pain and can help the skin of the fissure to heal more efficiently.

This targeted action makes Rectogesic more than a simple pain relief ointment. It addresses muscle spasm and impaired blood supply, which are key factors in chronic fissure discomfort.

Rectogesic GTN ointment should be used exactly as directed by your UK prescriber. Always follow their instructions and the patient information leaflet supplied with the medicine.

Typical Application Steps:

  • Wash and dry your hands.
  • Cover the tip of a finger with a finger cot, cling film, or disposable glove.
  • Express a 2.5 cm strip of ointment onto your finger.
  • Gently insert the finger into the anal canal up to the first joint and apply the ointment around the inside of the anus.
  • Apply Rectogesic GTN ointment every 12 hours or as prescribed.
  • Continue treatment for up to 8 weeks or until pain subsides.
  • Wash hands thoroughly after each use.

Do not exceed the recommended dose, and do not use more frequently than prescribed. If symptoms persist beyond the treatment period, complete a follow-up consultation so our prescriber can reassess your condition.

Rectogesic GTN ointment may be suitable for adults who:

  • Have chronic anal fissure pain that has not resolved with initial self-care.
  • Are experiencing significant rectal spasm contributing to pain and delayed healing.
  • Need a topical nitrate ointment to target both pain and blood supply issues.

Rectogesic GTN ointment is not suitable for:

  • Anyone under 18 years of age.
  • People allergic to glyceryl trinitrate or similar nitrates.
  • Those with low blood pressure or heart conditions worsened by nitrates unless closely monitored.
  • Anyone using other nitrate medications or PDE5 inhibitors like sildenafil products concurrently.
  • Patients who are pregnant or breastfeeding unless specifically advised by a prescriber.

Completing the online consultation helps our prescriber decide whether Rectogesic GTN ointment is appropriate based on your health and symptoms.

Rectogesic can cause side effects in some people, while others may not notice any unwanted effects at all.

Very Common Side Effects (Affect More Than 1 in 10 People):

  • Headache that may be severe initially and often reduces over time (this is frequently related to GTN absorption).

Common Side Effects (Up to 1 in 10 People):

  • Light-headedness.
  • Feeling sick.

Less Common Side Effects (Up to 1 in 100 People):

  • Local irritation, burning or itching around the anus.
  • Increased heart rate or palpitations.

Rare Side Effects:

  • Significant drop in blood pressure.
  • Severe allergic reactions.

If you notice anything serious or unusual after using Rectogesic GTN ointment, stop use and complete a follow-up consultation so our prescriber can advise you based on your condition.

Rectogesic GTN ointment is a targeted topical treatment for chronic anal fissure pain and associated muscle spasm. Its nitrate action not only reduces pain but also improves local blood flow, which can support quicker healing when conservative measures alone are not enough.

With Pharmacy Planet you get:

  • A UK prescriber review to confirm suitability.
  • Convenient online consultation at no extra cost before purchase.
  • Fast and discreet UK delivery to your door.

If you are looking for a prescription nitrate ointment that targets pain, improves local circulation and supports fissure healing, Rectogesic GTN ointment is a practical option worth discussing with your prescriber.

At Pharmacy Planet, getting access to Rectogesic GTN ointment online is straightforward and designed to ensure the treatment is appropriate for you.

  1. Complete the online consultation and tell us about your symptoms, pain levels and medical history.
  2. Our prescriber reviews your responses to decide if Rectogesic GTN ointment is suitable.
  3. If approved, your prescription is dispensed and delivered discreetly to your address.
Frequently Asked Questions

Rectogesic GTN ointment is prescribed mainly for chronic anal fissures. It can reduce pain linked to muscle spasm around the anus, which is why some people with piles discomfort may notice symptom relief. It is not a primary haemorrhoid treatment, so suitability must be confirmed during the consultation.

Rectogesic GTN ointment contains glyceryl trinitrate, which widens blood vessels. This effect can trigger headaches in some people, especially at the start of treatment. Headaches usually settle as the body adjusts, but they can be strong in the early days.

If you are prone to migraines, Rectogesic GTN ointment may increase the chance of headaches. This does not automatically rule it out, but it is important to mention migraine history during the online consultation so the prescriber can assess suitability.

Rectogesic GTN ointment should be applied just inside the anus, roughly up to the first finger joint. It does not need to be pushed deep inside. Gentle application is enough to reach the internal anal sphincter.

Rectogesic GTN ointment is designed for regular use, usually twice daily, for a limited treatment period. It should only be used exactly as prescribed and not for longer than advised without review.

A mild burning sensation can happen shortly after application, especially if the skin is very sore. This often eases quickly. If the burning is severe, persistent, or worsening, stop using the ointment and complete a follow-up consultation.

Rectogesic GTN ointment is not usually recommended during pregnancy or breastfeeding unless specifically assessed and approved by a UK prescriber. Always declare pregnancy or breastfeeding status in the consultation.

Rectogesic GTN ointment improves blood flow and reduces muscle spasm, which can support healing of the fissure. As the fissure heals, bleeding during bowel movements often reduces, but this can vary between individuals.

Rectogesic GTN ointment is often used alongside stool-softening treatments to reduce strain during bowel movements. Some painkillers are suitable, but nitrate interactions must be checked, so all medicines should be listed during the consultation.

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Authored on : April 6 2026

HARMINDER ‘HARMY’ KAUR

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GPhC Number: 2061107

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Reviewed on : April 6 2026

GURDEV SEHMI

BSc Pharm, MRPharmS, Independent Prescriber, Superintendent Pharmacist, Clinical Lead

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