Sumatriptan (generic Imigran) causes the blood vessels in the brain to contract. As some of the changes that occur in the brain to trigger a migraine attack are believed to involve the blood vessels widening, Sumatriptan helps reverse this process and relieve the symptoms of migraine. Sumatriptan effectively stimulates serotonin receptors in the brain, which cause the muscles surrounding the blood vessels in the brain to contract.
Sumatriptan also stabilises some of the chemical changes that occur in the brain during a migraine attack. The active ingredient is sumatriptan succinate.
Sumatriptan (generic Imigran) usually starts to work after 30 minutes, therefore it is important to take it as soon as possible after a migraine has started. Sumatriptan may not work for everyone; where it does not work, alternative triptans — such as almotriptan (Almogran) and frovatriptan (Migard) are worth trying.
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