Gastroesophageal reflux (also known as acid reflux) is a condition in which the mucosal lining of oesophagus becomes irritated or inflamed due to the presence of acid backing up from the stomach. Oesophagus, also known as the food pipe, connects the mouth to the stomach. When food reaches the stomach, it produces acid to aid digestion of food. However, the stomach cell lining is resistant to the action of acid while oesophagus does not have such features.

In normal circumstances, the lower sphincter muscle at the base of oesophagus prevents the backflow of acid, but in case of GERD, the acid enters the oesophagus creating a burning sensation.

Medicines for acid reflux like Lansoprazole and Pantoprazole are the most prescribed prescription heartburn tablets called as proton pump inhibitor. Proton pumps are found on cells that line the stomach and are used by these cells to produce stomach acid. These medicines work by inhibiting the action of the proton pumps and this reduces the production of stomach acid.

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