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Mezavant/Mesalazine

Mezavant is a prescription anti-inflammatory and is used for gastrointestinal disorders. Thanks to the sustained-release formulation, the active ingredient in this medication, mesalazine (from the aminosalicylate group), is released in a controlled manner. Excipients: acetylated monoglycerides, castor oil, colloidal silicon dioxide, ethylcellulose, hydroxypropyl methylcellulose, starch, stearic acid, sugar, talc, and Chinese wax. The active substance is mesalazine from the group of aminosalicylates. Mesalazine is believed to alleviate inflammation in the intestine by blocking the enzyme cyclooxygenase and inhibiting the production of prostaglandins in the intestinal wall.

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Price Comparison

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PackPrice (£)
Mezavant XL1200mg120 Tablets175.00
Mezavant XL1200mg180 tablets239.00
Mezavant XL1200mg60 Tablets95.00

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Mezavant Tablets | Mesalazine Modified-Release for Ulcerative Colitis

When gut inflammation becomes persistent, it can affect everything from your energy levels to your daily routine. Mezavant tablets are designed to treat inflammation in the colon, offering targeted ulcerative colitis relief and supporting long-term digestive health.

Containing Mesalazine, this prescription IBS drug (used where inflammation is involved) works directly in the bowel lining to reduce irritation and restore balance in the gut.

What Are Mezavant Tablets Used For?

Mezavant tablets are used to treat ulcerative colitis and other inflammatory bowel conditions affecting the colon. They are commonly prescribed for:

  • Active ulcerative colitis flare-ups.
  • Preventing recurrence of inflammation.
  • Long-term bowel inflammation treatment.
  • Managing symptoms linked to gut inflammation.

This medicine focuses on reducing inflammation rather than muscle spasms, making it suitable for inflammatory conditions rather than standard IBS alone.

How Mezavant Tablets Work in the Gut

Mezavant tablets work by reducing inflammation throughout the colon and rectum. The active ingredient Mesalazine acts as an anti-inflammatory gut therapy, targeting the lining of the bowel where irritation occurs. It works by:

  • Reducing swelling and redness in the colon.
  • Supporting healing of the gut lining.
  • Improving symptoms such as diarrhoea and abdominal discomfort.
  • Maintaining stable colon care when taken regularly.

Its modified-release design ensures the medicine works across the entire colon for consistent effect.

How to Take Mezavant Tablets

Mezavant tablets should be taken once daily with food, exactly as prescribed during your consultation with Pharmacy Planet.

General guidance:

  • Swallow the tablets whole with water.
  • Do not crush or chew the tablets.
  • Take at the same time each day.

Typical dosage: During flare-ups: A higher daily dose (usually 2.4g to 4.8g) may be prescribed. Maintenance phase: A lower daily dose (commonly 2.4g) is used to prevent symptoms from returning.

Important tips: Take the tablets with food to support proper absorption. Drink plenty of fluids, especially during episodes of diarrhoea, vomiting, or fever. Continue taking the medicine regularly, even if you feel better, unless advised otherwise.

Consistent use supports effective bowel inflammation treatment and reduces flare-up risk.

Who Can Use Mezavant Tablets?

Mezavant tablets are suitable for adults with ulcerative colitis or inflammatory bowel conditions. They may be appropriate for:

  • Adults needing long-term anti-inflammatory gut therapy.
  • Patients managing recurring inflammation.
  • Individuals requiring structured colon care.

This medicine is not typically recommended for children under 18.

Who Should Not Take Mezavant Tablets?

Mezavant tablets may not be suitable for people with certain medical conditions. Avoid this medicine if you:

  • Are allergic to Mesalazine or salicylates (such as aspirin).
  • Have severe kidney or liver problems.

Take extra care if you:

  • Have a history of heart inflammation.
  • Have digestive blockages or narrowing of the gut.
  • Have lung conditions or chronic illness.

A consultation ensures safe use of this prescription bowel medication.

Possible Side Effects of Mezavant Tablets

Like all medicines, Mezavant tablets can cause side effects, although many people tolerate them well.

Common side effects:

  • Headache.
  • Stomach pain or bloating.
  • Nausea or vomiting.
  • Diarrhoea or indigestion.
  • Feeling tired or weak.

Serious side effects:

  • Severe abdominal pain with bloody diarrhoea.
  • Allergic reactions such as swelling or rash.
  • Signs of infection such as fever or sore throat.
  • Kidney or liver-related symptoms.

Seek urgent medical attention if serious symptoms occur.

Possible Interactions with Mezavant Tablets

Mezavant tablets can interact with medicines that affect the immune system or blood clotting. Tell your prescriber if you take:

  • Anti-inflammatory medicines (such as NSAIDs).
  • Immunosuppressants.
  • Blood-thinning medicines.
  • Other Mesalazine-based treatments.

This ensures safe and effective digestive care.

Important Advice Before Taking Mezavant Tablets

Monitoring is required before and during treatment with Mezavant tablets. You may need:

  • Blood tests before starting treatment.
  • Regular kidney and liver function checks.

Additional advice:

  • Stay well hydrated, especially during illness.
  • Inform healthcare professionals before lab tests.

This ensures safe and effective long-term bowel therapy.

Why Do People Choose Mezavant Tablets?

Mezavant tablets are chosen for their targeted, once-daily approach to managing bowel inflammation. People often prefer this treatment because:

  • It delivers Mesalazine gradually throughout the colon.
  • It supports both symptom control and prevention.
  • It fits easily into a daily routine with once-daily dosing.
  • It provides consistent support for long-term gut health.

For many, it becomes an essential part of structured digestive care.

Mesalazine & Bowel Inflammation Treatments

These medicines are used to reduce inflammation in the bowel and are commonly prescribed for inflammatory bowel conditions such as ulcerative colitis. The table below compares commonly prescribed bowel inflammation treatments and how they are typically used.

ProductWhat it isWhat it's mainly used forHow you usually use itWhat to expect
Asacol / Mesalazine TabletsMesalazine anti-inflammatory tabletsUlcerative colitis and bowel inflammationTaken regularly as prescribedHelps reduce inflammation inside the bowel.
Mezavant / Mesalazine TabletsLong-acting mesalazine tabletsUlcerative colitisTaken once dailyDesigned for slow release throughout the bowel.
Octasa / Mesalazine TabletsMesalazine tabletsInflammatory bowel conditionsTaken regularlyHelps maintain symptom control and reduce flare-ups.
Pentasa / Mesalazine TabletsMesalazine tabletsBowel inflammationTaken regularlySlow-release treatment for ongoing inflammation control.
Pentasa / Mesalazine SachetsMesalazine granule sachetsUlcerative colitis and bowel inflammationTaken as prescribedSachet form may be easier for some people than tablets.
Salofalk / Mesalazine TabletsMesalazine tabletsInflammatory bowel diseaseTaken regularlyHelps manage bowel inflammation over time.
Salofalk / Mesalazine SachetsMesalazine granule sachetsBowel inflammationTaken as prescribedGranule form designed for bowel delivery.
Colazide / Balsalazide CapsulesAnti-inflammatory bowel capsulesUlcerative colitisTaken regularlyTargets inflammation in the large bowel.
OlsalazineAnti-inflammatory bowel medicineUlcerative colitisTaken regularlyHelps reduce bowel inflammation and maintain remission.
Sulfasalazine / Salazopyrin TabletsAnti-inflammatory bowel tabletsUlcerative colitis and inflammatory bowel conditionsTaken regularlyHelps control bowel inflammation and symptoms.

Important: This comparison is for general information only and does not replace medical advice. A prescriber will decide which treatment is suitable for you following an online consultation.

How to Order Mezavant Tablets Online from Pharmacy Planet

Ordering Mezavant tablets is simple and secure.

  1. Complete a Short Online Consultation — Provide details about your symptoms and health.
  2. Prescription Review — A UK-registered prescriber confirms if Mezavant tablets are suitable.
  3. Discreet Delivery — If approved, your treatment is delivered directly to your chosen address.
Mezavant/Mesalazine Tablets

When gut inflammation becomes persistent, it can affect everything from your energy levels to your daily routine. Mezavant tablets are designed to treat inflammation in the colon, offering targeted ulcerative colitis relief and supporting long-term digestive health.

Containing Mesalazine, this prescription IBS drug (used where inflammation is involved) works directly in the bowel lining to reduce irritation and restore balance in the gut.

Mezavant tablets are used to treat ulcerative colitis and other inflammatory bowel conditions affecting the colon. They are commonly prescribed for:

  • Active ulcerative colitis flare-ups.
  • Preventing recurrence of inflammation.
  • Long-term bowel inflammation treatment.
  • Managing symptoms linked to gut inflammation.

This medicine focuses on reducing inflammation rather than muscle spasms, making it suitable for inflammatory conditions rather than standard IBS alone.

Mezavant tablets work by reducing inflammation throughout the colon and rectum. The active ingredient Mesalazine acts as an anti-inflammatory gut therapy, targeting the lining of the bowel where irritation occurs. It works by:

  • Reducing swelling and redness in the colon.
  • Supporting healing of the gut lining.
  • Improving symptoms such as diarrhoea and abdominal discomfort.
  • Maintaining stable colon care when taken regularly.

Its modified-release design ensures the medicine works across the entire colon for consistent effect.

Mezavant tablets should be taken once daily with food, exactly as prescribed during your consultation with Pharmacy Planet.

General guidance:

  • Swallow the tablets whole with water.
  • Do not crush or chew the tablets.
  • Take at the same time each day.

Typical dosage: During flare-ups: A higher daily dose (usually 2.4g to 4.8g) may be prescribed. Maintenance phase: A lower daily dose (commonly 2.4g) is used to prevent symptoms from returning.

Important tips: Take the tablets with food to support proper absorption. Drink plenty of fluids, especially during episodes of diarrhoea, vomiting, or fever. Continue taking the medicine regularly, even if you feel better, unless advised otherwise.

Consistent use supports effective bowel inflammation treatment and reduces flare-up risk.

Mezavant tablets are suitable for adults with ulcerative colitis or inflammatory bowel conditions. They may be appropriate for:

  • Adults needing long-term anti-inflammatory gut therapy.
  • Patients managing recurring inflammation.
  • Individuals requiring structured colon care.

This medicine is not typically recommended for children under 18.

Mezavant tablets may not be suitable for people with certain medical conditions. Avoid this medicine if you:

  • Are allergic to Mesalazine or salicylates (such as aspirin).
  • Have severe kidney or liver problems.

Take extra care if you:

  • Have a history of heart inflammation.
  • Have digestive blockages or narrowing of the gut.
  • Have lung conditions or chronic illness.

A consultation ensures safe use of this prescription bowel medication.

Like all medicines, Mezavant tablets can cause side effects, although many people tolerate them well.

Common side effects:

  • Headache.
  • Stomach pain or bloating.
  • Nausea or vomiting.
  • Diarrhoea or indigestion.
  • Feeling tired or weak.

Serious side effects:

  • Severe abdominal pain with bloody diarrhoea.
  • Allergic reactions such as swelling or rash.
  • Signs of infection such as fever or sore throat.
  • Kidney or liver-related symptoms.

Seek urgent medical attention if serious symptoms occur.

Mezavant tablets can interact with medicines that affect the immune system or blood clotting. Tell your prescriber if you take:

  • Anti-inflammatory medicines (such as NSAIDs).
  • Immunosuppressants.
  • Blood-thinning medicines.
  • Other Mesalazine-based treatments.

This ensures safe and effective digestive care.

Monitoring is required before and during treatment with Mezavant tablets. You may need:

  • Blood tests before starting treatment.
  • Regular kidney and liver function checks.

Additional advice:

  • Stay well hydrated, especially during illness.
  • Inform healthcare professionals before lab tests.

This ensures safe and effective long-term bowel therapy.

Mezavant tablets are chosen for their targeted, once-daily approach to managing bowel inflammation. People often prefer this treatment because:

  • It delivers Mesalazine gradually throughout the colon.
  • It supports both symptom control and prevention.
  • It fits easily into a daily routine with once-daily dosing.
  • It provides consistent support for long-term gut health.

For many, it becomes an essential part of structured digestive care.

Mesalazine & Bowel Inflammation Treatments

These medicines are used to reduce inflammation in the bowel and are commonly prescribed for inflammatory bowel conditions such as ulcerative colitis. The table below compares commonly prescribed bowel inflammation treatments and how they are typically used.

ProductWhat it isWhat it's mainly used forHow you usually use itWhat to expect
Asacol / Mesalazine TabletsMesalazine anti-inflammatory tabletsUlcerative colitis and bowel inflammationTaken regularly as prescribedHelps reduce inflammation inside the bowel.
Mezavant / Mesalazine TabletsLong-acting mesalazine tabletsUlcerative colitisTaken once dailyDesigned for slow release throughout the bowel.
Octasa / Mesalazine TabletsMesalazine tabletsInflammatory bowel conditionsTaken regularlyHelps maintain symptom control and reduce flare-ups.
Pentasa / Mesalazine TabletsMesalazine tabletsBowel inflammationTaken regularlySlow-release treatment for ongoing inflammation control.
Pentasa / Mesalazine SachetsMesalazine granule sachetsUlcerative colitis and bowel inflammationTaken as prescribedSachet form may be easier for some people than tablets.
Salofalk / Mesalazine TabletsMesalazine tabletsInflammatory bowel diseaseTaken regularlyHelps manage bowel inflammation over time.
Salofalk / Mesalazine SachetsMesalazine granule sachetsBowel inflammationTaken as prescribedGranule form designed for bowel delivery.
Colazide / Balsalazide CapsulesAnti-inflammatory bowel capsulesUlcerative colitisTaken regularlyTargets inflammation in the large bowel.
OlsalazineAnti-inflammatory bowel medicineUlcerative colitisTaken regularlyHelps reduce bowel inflammation and maintain remission.
Sulfasalazine / Salazopyrin TabletsAnti-inflammatory bowel tabletsUlcerative colitis and inflammatory bowel conditionsTaken regularlyHelps control bowel inflammation and symptoms.

Important: This comparison is for general information only and does not replace medical advice. A prescriber will decide which treatment is suitable for you following an online consultation.

Ordering Mezavant tablets is simple and secure.

  1. Complete a Short Online Consultation — Provide details about your symptoms and health.
  2. Prescription Review — A UK-registered prescriber confirms if Mezavant tablets are suitable.
  3. Discreet Delivery — If approved, your treatment is delivered directly to your chosen address.
Frequently Asked Questions

Mezavant starts working from the first dose, but most people notice symptom improvement within a few weeks. Full control of inflammation can take longer with regular use.

Yes, by reducing inflammation in the colon, Mezavant can reduce bleeding linked to ulcerative colitis and improve bowel symptoms over time.

Mezavant is often used to keep inflammation under control. Taking it daily prevents flare-ups, even when symptoms are not currently present.

Chewing or breaking the tablets stops the controlled release of the medicine. This means it may not reach the colon properly and may not work as intended.

Some people notice mild digestive changes at the beginning. This usually settles, but if diarrhoea becomes severe or persistent, speak to your prescriber.

They contain the same active ingredient, Mesalazine, but release the medicine differently in the gut. This means one may suit your condition better than another.

Yes, it is sometimes used together with steroid treatment during more severe flare-ups, depending on your treatment plan.

In rare cases, they can affect the kidneys. Regular blood and urine tests are carried out to make sure everything remains safe during treatment.

It is best to leave a gap between them. Some indigestion medicines can affect how Mezavant releases in the gut.

Yes, many people take it long-term to keep inflammation controlled and maintain stable gut health, especially in ulcerative colitis.

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Review By

HARMINDER ‘HARMY’ KAUR

Last Updated On : Mar 13 2026

BSc(hons) Pharmacy

GPhC Number: 2061107

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GURDEV SEHMI

Last Reviewed On : Mar 23 2026

BSc Pharm, MRPharmS, Independent Prescriber, Superintendent Pharmacist, Clinical Lead

GPhC Number: 2050925