Lotriderm is a medicinal cream with an antifungal or antifungal action, that is, functioning as an eczema treatment medication, it causes the death of fungi that develop in some body tissues. Therefore, it is used to treat infections caused by these organisms.
Lotriderm kills fungi by binding to their cell walls and preventing them from synthesizing ergosterol, a cholesterol-like compound necessary for fungi to maintain their cell membranes. The Lotriderm ingredients consist of betamethasone dipropionate and clotrimazole.
Lotriderm Cream is indicated for the topical treatment of the following dermal infections: Tinea pedis, Tinea fever, and Tinea due to Trichophyton rubrum, Trichophyton mentagrophytes, Epidermophyton floccosum, and Microsporum canis and candidiasis caused by Candida albicans. The cream combines the broad-spectrum antifungal action of clotrimazole with the sustained anti-inflammatory, antipruritic, and vasoconstrictive effects of betamethasone dipropionate.
Like all medicines, this medicine can cause side effects, although not everybody gets them.
The following side effects have been reported, very rarely, with the use of Celestoderm cream: allergies, rashes, and changes in skin color.
Treatment with gentamicin has produced transient irritation (erythema and itching) that generally has not required interruption of the treatment.
The following reactions have been reported with the use of topical corticosteroids, especially after prolonged application, in large areas, with bandages or occlusive materials, and/or in children, below is a list of the known Lotriderm side effects:
- Thinning of the skin (atrophy)
- Dryness or cracking of the skin
- Itching or burning
- Redness (erythema)
- The appearance of red spots
- Bruising
- Inflammation of hair follicles (folliculitis)
- Skin stretch marks
- Acne
- Allergic skin reaction (contact dermatitis)
- Infections
Adverse effects can occur not only in the treated area but also in completely different areas of the body, which occurs if the active ingredient passes through the skin to the body.
This, for example, can increase pressure in the eye (glaucoma) or could lead to a condition characterized by round face, fat accumulation, hump, delayed healing, psychiatric symptoms, etc. (Cushing's syndrome); increased blood pressure, fluid retention (edema), decreased blood potassium levels (hypokalemia), osteoporosis, thyroid abnormalities (hyperthyroidism), increased cholesterol and triglycerides, increased blood sugar levels (hyperglycemia ), gastric ulcer, cataracts, blurred vision with frequency not known (frequency cannot be estimated from the available data), hair loss, hair growth, specific inflammation of the skin around the upper lip and chin (dermatitis perioral), changes in skin color, paresthesia (an abnormal sensation of the skin, such as numbness, tingling, stinging, burning, or tickling of the skin).
Lotriderm precautions
Lotriderm Cream should not be used with the occlusive dressing technique. If irritation or sensitization occurs with the use of Lotriderm products, treatment should be discontinued and appropriate therapeutic measures instituted. In the presence of bacterial infection, an appropriate antibacterial agent should be administered concomitantly. When an adequate response to Lotridrerm Cream is not observed, appropriate microbiological studies should be repeated to confirm the diagnosis and to rule out the possibility of other responsible pathogens before instituting another course of antifungal therapy. Any of the reported side effects after systemic corticosteroid use, including adrenal suppression, manifestations of Cushing's syndrome, hyperglycemia, and glycosuria, can also occur with topical corticosteroids.