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Lotriderm Cream | Betamethasone & Clotrimazole for Fungal Skin Infections & Inflammation

Lotriderm is a cream for skin inflammation with infections caused by fungi; it contains Betamethasone dipropionate, a corticoid, and clotrimazole, an antifungal. Lotriderm is indicated for the local treatment of skin inflammation with infections caused by fungi sensitive to clotrimazole: tinea pedis, tinea cruris, and tinea corporis, and candidiasis. Apply a bit of Lotriderm cream to the affected skin and massage gently. The treated skin should not be wet for at least half an hour to prevent the medicine from rinsing. Do not stain the product on and around the eyelids and avoid direct eye contact.

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Lotriderm Cream | Betamethasone & Clotrimazole for Fungal Skin Infections & Inflammation
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Starts at £21.00
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Lotriderm-30g x 1 Tube21.00
Lotriderm-30g x 2 Tubes34.00

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Lotriderm Cream is a combination treatment which contains betamethasone dipropionate (a potent corticosteroid) and clotrimazole (an antifungal agent), designed to treat inflammatory skin conditions that are also affected by fungal infections. This medicine is usually prescribed for conditions like ringworm of the body, jock itch, and athlete’s foot. The corticosteroid component, betamethasone, helps reduce redness, swelling, and itching, while clotrimazole targets fungal infections, disrupting its fungal cell membrane.

What is Lotriderm?

Lotriderm is a medicinal cream with an antifungal or antifungal action, that is, functioning as an eczema treatment medication, it causes the death of fungi that develop in some body tissues. Therefore, it is used to treat infections caused by these organisms.

Lotriderm kills fungi by binding to their cell walls and preventing them from synthesizing ergosterol, a cholesterol-like compound necessary for fungi to maintain their cell membranes. The Lotriderm ingredients consist of betamethasone dipropionate and clotrimazole.

How does it work?

This itching and redness treatment medicinal cream works as a fungal infection treatment medication, thanks to its main active ingredients, Clotrimazole and betamethasone, The sustained anti-inflammatory, antipruritic, and vasoconstrictive effects of betamethasone are combined with the broad-spectrum antifungal action of clotrimazole.

What are the benefits of taking it?

Lotriderm Cream is indicated for the topical treatment of the following dermal infections: Tinea pedis, Tinea fever, and Tinea due to Trichophyton rubrum, Trichophyton mentagrophytes, Epidermophyton floccosum, and Microsporum canis and candidiasis caused by Candida albicans. The cream combines the broad-spectrum antifungal action of clotrimazole with the sustained anti-inflammatory, antipruritic, and vasoconstrictive effects of betamethasone dipropionate.

How do I use it?

Apply a bit of this Psoriasis Medication to the affected skin and massage gently. The treated skin should not be wet for at least half an hour to prevent the medicine from rinsing. Do not stain the product on and around the eyelids and avoid direct eye contact. Wash your hands well after using it. Hormone-containing skin creams should not be used for long. For this reason, your doctor will only prescribe Lotriderm for two to four weeks. If you don't notice any improvement after a week or two, contact your doctor.

Its dosage

Unless the doctor indicates otherwise, the generally recommended dose of Lotriderm is as follows:

Adults and children: apply the cream to the affected skin twice a day.

Do not cover the treated skin unless your doctor tells you to. Young children can only use Lotriderm after medical advice. The doctor determines how long you need to use this medicine.

Side effects & precautions

Like all medicines, this medicine can cause side effects, although not everybody gets them.

The following side effects have been reported, very rarely, with the use of Celestoderm cream: allergies, rashes, and changes in skin color.

Treatment with gentamicin has produced transient irritation (erythema and itching) that generally has not required interruption of the treatment.

The following reactions have been reported with the use of topical corticosteroids, especially after prolonged application, in large areas, with bandages or occlusive materials, and/or in children, below is a list of the known Lotriderm side effects:

  • Thinning of the skin (atrophy)
  • Dryness or cracking of the skin
  • Itching or burning
  • Redness (erythema)
  • The appearance of red spots
  • Bruising
  • Inflammation of hair follicles (folliculitis)
  • Skin stretch marks
  • Acne
  • Allergic skin reaction (contact dermatitis)
  • Infections

Adverse effects can occur not only in the treated area but also in completely different areas of the body, which occurs if the active ingredient passes through the skin to the body.

This, for example, can increase pressure in the eye (glaucoma) or could lead to a condition characterized by round face, fat accumulation, hump, delayed healing, psychiatric symptoms, etc. (Cushing's syndrome); increased blood pressure, fluid retention (edema), decreased blood potassium levels (hypokalemia), osteoporosis, thyroid abnormalities (hyperthyroidism), increased cholesterol and triglycerides, increased blood sugar levels (hyperglycemia ), gastric ulcer, cataracts, blurred vision with frequency not known (frequency cannot be estimated from the available data), hair loss, hair growth, specific inflammation of the skin around the upper lip and chin (dermatitis perioral), changes in skin color, paresthesia (an abnormal sensation of the skin, such as numbness, tingling, stinging, burning

Buying Lotriderm online

You can buy Lotriderm Cream online through one of the UK’s leading online pharmacies, Pharmacy Planet. It's easy and convenient. You will need to fill out a short assessment and the item will be delivered directly to your door. If you want to buy Lotriderm online, use Pharmacy Planet, a UK pharmacy you can trust.

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Lotriderm is a medicinal cream with an antifungal or antifungal action, that is, functioning as an eczema treatment medication, it causes the death of fungi that develop in some body tissues. Therefore, it is used to treat infections caused by these organisms.

Lotriderm kills fungi by binding to their cell walls and preventing them from synthesizing ergosterol, a cholesterol-like compound necessary for fungi to maintain their cell membranes. The Lotriderm ingredients consist of betamethasone dipropionate and clotrimazole.

This itching and redness treatment medicinal cream works as a fungal infection treatment medication, thanks to its main active ingredients, Clotrimazole and betamethasone, The sustained anti-inflammatory, antipruritic, and vasoconstrictive effects of betamethasone are combined with the broad-spectrum antifungal action of clotrimazole.

Lotriderm Cream is indicated for the topical treatment of the following dermal infections: Tinea pedis, Tinea fever, and Tinea due to Trichophyton rubrum, Trichophyton mentagrophytes, Epidermophyton floccosum, and Microsporum canis and candidiasis caused by Candida albicans. The cream combines the broad-spectrum antifungal action of clotrimazole with the sustained anti-inflammatory, antipruritic, and vasoconstrictive effects of betamethasone dipropionate.

Apply a bit of this Psoriasis Medication to the affected skin and massage gently. The treated skin should not be wet for at least half an hour to prevent the medicine from rinsing. Do not stain the product on and around the eyelids and avoid direct eye contact. Wash your hands well after using it. Hormone-containing skin creams should not be used for long. For this reason, your doctor will only prescribe Lotriderm for two to four weeks. If you don't notice any improvement after a week or two, contact your doctor.

Unless the doctor indicates otherwise, the generally recommended dose of Lotriderm is as follows:

Adults and children: apply the cream to the affected skin twice a day.

Do not cover the treated skin unless your doctor tells you to. Young children can only use Lotriderm after medical advice. The doctor determines how long you need to use this medicine.

Like all medicines, this medicine can cause side effects, although not everybody gets them.

The following side effects have been reported, very rarely, with the use of Celestoderm cream: allergies, rashes, and changes in skin color.

Treatment with gentamicin has produced transient irritation (erythema and itching) that generally has not required interruption of the treatment.

The following reactions have been reported with the use of topical corticosteroids, especially after prolonged application, in large areas, with bandages or occlusive materials, and/or in children, below is a list of the known Lotriderm side effects:

  • Thinning of the skin (atrophy)
  • Dryness or cracking of the skin
  • Itching or burning
  • Redness (erythema)
  • The appearance of red spots
  • Bruising
  • Inflammation of hair follicles (folliculitis)
  • Skin stretch marks
  • Acne
  • Allergic skin reaction (contact dermatitis)
  • Infections

Adverse effects can occur not only in the treated area but also in completely different areas of the body, which occurs if the active ingredient passes through the skin to the body.

This, for example, can increase pressure in the eye (glaucoma) or could lead to a condition characterized by round face, fat accumulation, hump, delayed healing, psychiatric symptoms, etc. (Cushing's syndrome); increased blood pressure, fluid retention (edema), decreased blood potassium levels (hypokalemia), osteoporosis, thyroid abnormalities (hyperthyroidism), increased cholesterol and triglycerides, increased blood sugar levels (hyperglycemia ), gastric ulcer, cataracts, blurred vision with frequency not known (frequency cannot be estimated from the available data), hair loss, hair growth, specific inflammation of the skin around the upper lip and chin (dermatitis perioral), changes in skin color, paresthesia (an abnormal sensation of the skin, such as numbness, tingling, stinging, burning

You can buy Lotriderm Cream online through one of the UK’s leading online pharmacies, Pharmacy Planet. It's easy and convenient. You will need to fill out a short assessment and the item will be delivered directly to your door. If you want to buy Lotriderm online, use Pharmacy Planet, a UK pharmacy you can trust.

Frequently Asked Questions

No, Lotriderm Cream cannot be used for bacterial skin infections, as this is not what it is licensed for. As it is formulated to target fungal infections, it may prove to be ineffective for irritated skin with a bacterial infection. If you do have a bacterial skin infection, consult your healthcare professional to discuss an alternative and more appropriate treatment.

You should only use Lotriderm Cream while pregnant or breastfeeding if you have been advised to do so by a healthcare provider. There is limited research regarding the safety of Lotriderm in these circumstances, so a healthcare provider will be able to guide you towards a treatment that is safe for both you and your baby.

Yes, you can apply moisturisers with Lotriderm Cream, as this can help keep the skin hydrated. Make sure to apply your moisturiser at least 30 minutes after applying Lotriderm to ensure that the medicine has had enough time to be absorbed into the skin. Additionally, ensure that your moisturiser is fragrance-free and does not contain harsh chemicals to avoid further irritation.

If you miss a dose of Lotriderm Cream, apply it as soon as you remember. However, if it is almost time for your next scheduled application, skip the missed dose and continue with your routine. Do not apply two doses at once, as this may increase the risk of side effects. To get the most benefit from your treatment, use the cream consistently as directed by your healthcare provider.

Like all medicines, Lotriderm can cause side effects. Some people have experienced localised skin reactions such as burning, itching, or redness. If you use this medicine for an extended period, it can lead to slightly more severe side effects, such as skin thinning and stretch marks.

Lotriderm Cream is not recommended for use in children under the age of 12 unless advised and prescribed by a healthcare professional. Children have more sensitive skin, which makes them more susceptible to side effects due to higher absorption rates. Always follow your healthcare provider’s guidance when using this medicine for children.

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Authored on : May 11 2026

Gurudev Sahmi

BSc Pharm, MRPharmS, Independent Prescriber, Superintendent Pharmacist, Clinical Lead

GPhC Number: 2050925

Pharmacist Image

Reviewed on : May 11 2026

Gurudev Sahmi

BSc Pharm, MRPharmS, Independent Prescriber, Superintendent Pharmacist, Clinical Lead

2050925