Lixiana Edoxaban
Lixiana is indicated for the prevention of stroke and systemic embolism in adult patients with nonvalvular atrial fibrillation (NVAF) with one or more risk factors such as congestive heart failure, hypertension, age ≥ 75 years, diabetes mellitus, stroke or attack Transient ischemic disease (TIA). Lixiana is indicated for the treatment of deep vein thrombosis (DVT) and pulmonary embolism (PD), and for the prevention of recurrences of DVT and PD in adults. The recommended dose is one 60 mg tablet once a day.
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| Pack | Price (£) | ||
|---|---|---|---|
| - | 30mg | 28 Tablets | 112.00 |
| - | 30mg | 56 Tablets | 214.00 |
| - | 30mg | 84 Tablets | 317.00 |
| - | 60mg | 28 Tablets | 112.00 |
| - | 60mg | 56 Tablets | 214.00 |
| - | 60mg | 84 Tablets | 317.00 |
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Lixiana Tablets for Stroke Prevention and Anticoagulation Therapy
Lixiana tablets protect against serious blood clots in people with certain heart and circulation problems. They are prescribed for atrial fibrillation and for the treatment and prevention of clots in the veins or lungs, where sustained anticoagulant therapy is required.
Lixiana contains edoxaban, a modern blood thinner that targets a key clotting factor in the blood. When taken regularly, it supports heart health, protects the circulatory system, and reduces the risk of stroke and other clot-related complications.
If approved after an online consultation, you can get Lixiana tablets securely from Pharmacy Planet as part of your long-term anticoagulation or stroke-prevention treatment plan.
What Are Lixiana Tablets?
Lixiana tablets are a prescription-only anticoagulant used to prevent and treat blood clots.
Each tablet contains edoxaban, which belongs to a group of medicines called Factor Xa inhibitors. These medicines reduce the blood's ability to clot, lowering the risk of thromboembolism without the need for routine blood monitoring.
Lixiana is widely prescribed for stroke prevention in non-valvular atrial fibrillation and for preventing blood clots in the legs and lungs from returning.
How Do Lixiana Tablets Work?
Blood clots form through a chain reaction involving clotting proteins. Lixiana blocks one of the most important steps in this process.
1. Blocks Factor Xa
Edoxaban blocks Factor Xa, a key protein involved in blood clot formation.
2. Reduces Blood Clot Formation
By slowing clotting activity, the risk of clots forming in blood vessels is reduced.
3. Protects Against Stroke and Embolism
In atrial fibrillation, Lixiana lowers the risk of clots travelling to the brain or other organs.
This targeted action makes Lixiana a trusted option in modern anticoagulation therapy.
How to Take Lixiana Tablets?
Always take Lixiana tablets exactly as prescribed by your prescriber.
Dosage Guidance:
- The standard dose is Lixiana 60 mg taken once daily.
- The dose may be reduced to Lixiana 30 mg once daily if you have reduced kidney function or specific kidney function considerations.
- A reduced dose may also apply if your body weight is 60 kg or less.
- A reduced dose may also apply if you take certain medicines that affect how Lixiana is processed.
Your prescriber will confirm the correct dose during your consultation. Do not change your dose without medical advice.
General Instructions for Use:
- Swallow the tablet with water.
- Lixiana can be taken with or without food.
- Take the tablet at the same time each day.
- Tablets can be crushed and mixed with water or apple purée if swallowing is difficult.
- Do not stop taking Lixiana without medical advice, as this increases the risk of serious blood clots.
Who Can Use Lixiana Tablets?
Lixiana tablets may be suitable for adults who:
- Have non-valvular atrial fibrillation with risk factors for stroke.
- Are being treated for deep vein thrombosis or pulmonary embolism.
- Need long-term thromboembolism prevention.
- Require ongoing anticoagulation therapy for cardiovascular health.
Lixiana tablets may not be suitable if you:
- Are allergic to edoxaban or any tablet ingredients.
- Have active or uncontrolled bleeding.
- Have conditions that increase serious bleeding risk.
- Have severe liver disease linked to bleeding.
- Have uncontrolled high blood pressure.
- Are pregnant or breastfeeding.
A UK prescriber will review your medical history during your Pharmacy Planet consultation to confirm suitability.
Possible Side Effects of Lixiana Tablets
Lixiana, like other medicines, may be associated with side effects, although these do not affect everyone.
Common Side Effects:
- Nosebleeds or easy bruising
- Bleeding from the gums or skin
- Stomach pain or nausea
- Headache or dizziness
- Tiredness or weakness linked to anaemia
Serious Side Effects:
- Bleeding that does not stop
- Blood in urine or stools
- Sudden weakness, severe headache, or collapse
- Signs of a serious allergic reaction
Seek urgent medical attention if you notice heavy or unexplained bleeding.
Possible Interactions with Lixiana Tablets
Some medicines can increase bleeding risk or reduce how Lixiana works.
Tell your prescriber if you take:
- Other anticoagulants or blood thinners.
- Anti-inflammatory painkillers such as acetylsalicylic acid or naproxen.
- Certain antibiotics or antifungal medicines.
- Medicines for heart rhythm problems.
- Epilepsy medicines or St John's Wort.
- Some antidepressants.
Why Do People Choose Lixiana Tablets?
Lixiana tablets are often chosen because they:
- Reduce the risk of stroke in atrial fibrillation.
- Prevent blood clots in the veins and lungs.
- Are taken once daily for convenience.
- Do not require routine blood monitoring.
- Fit easily into long-term cardiovascular treatment plans.
Many people find Lixiana provides steady, dependable protection against blood clots.
How Does the Online Consultation and Ordering Process Work at Pharmacy Planet?
Getting Lixiana tablets from Pharmacy Planet is simple:
- Complete the online consultation and share details about your heart condition and current medicines.
- A UK-registered prescriber checks whether Lixiana is suitable for you.
- If approved, your prescription is confirmed.
- Your medication is dispensed and delivered discreetly.
Lixiana tablets protect against serious blood clots in people with certain heart and circulation problems. They are prescribed for atrial fibrillation and for the treatment and prevention of clots in the veins or lungs, where sustained anticoagulant therapy is required.
Lixiana contains edoxaban, a modern blood thinner that targets a key clotting factor in the blood. When taken regularly, it supports heart health, protects the circulatory system, and reduces the risk of stroke and other clot-related complications.
If approved after an online consultation, you can get Lixiana tablets securely from Pharmacy Planet as part of your long-term anticoagulation or stroke-prevention treatment plan.
Lixiana tablets are a prescription-only anticoagulant used to prevent and treat blood clots.
Each tablet contains edoxaban, which belongs to a group of medicines called Factor Xa inhibitors. These medicines reduce the blood's ability to clot, lowering the risk of thromboembolism without the need for routine blood monitoring.
Lixiana is widely prescribed for stroke prevention in non-valvular atrial fibrillation and for preventing blood clots in the legs and lungs from returning.
Blood clots form through a chain reaction involving clotting proteins. Lixiana blocks one of the most important steps in this process.
1. Blocks Factor Xa
Edoxaban blocks Factor Xa, a key protein involved in blood clot formation.
2. Reduces Blood Clot Formation
By slowing clotting activity, the risk of clots forming in blood vessels is reduced.
3. Protects Against Stroke and Embolism
In atrial fibrillation, Lixiana lowers the risk of clots travelling to the brain or other organs.
This targeted action makes Lixiana a trusted option in modern anticoagulation therapy.
Always take Lixiana tablets exactly as prescribed by your prescriber.
Dosage Guidance:
- The standard dose is Lixiana 60 mg taken once daily.
- The dose may be reduced to Lixiana 30 mg once daily if you have reduced kidney function or specific kidney function considerations.
- A reduced dose may also apply if your body weight is 60 kg or less.
- A reduced dose may also apply if you take certain medicines that affect how Lixiana is processed.
Your prescriber will confirm the correct dose during your consultation. Do not change your dose without medical advice.
General Instructions for Use:
- Swallow the tablet with water.
- Lixiana can be taken with or without food.
- Take the tablet at the same time each day.
- Tablets can be crushed and mixed with water or apple purée if swallowing is difficult.
- Do not stop taking Lixiana without medical advice, as this increases the risk of serious blood clots.
Lixiana tablets may be suitable for adults who:
- Have non-valvular atrial fibrillation with risk factors for stroke.
- Are being treated for deep vein thrombosis or pulmonary embolism.
- Need long-term thromboembolism prevention.
- Require ongoing anticoagulation therapy for cardiovascular health.
Lixiana tablets may not be suitable if you:
- Are allergic to edoxaban or any tablet ingredients.
- Have active or uncontrolled bleeding.
- Have conditions that increase serious bleeding risk.
- Have severe liver disease linked to bleeding.
- Have uncontrolled high blood pressure.
- Are pregnant or breastfeeding.
A UK prescriber will review your medical history during your Pharmacy Planet consultation to confirm suitability.
Lixiana, like other medicines, may be associated with side effects, although these do not affect everyone.
Common Side Effects:
- Nosebleeds or easy bruising
- Bleeding from the gums or skin
- Stomach pain or nausea
- Headache or dizziness
- Tiredness or weakness linked to anaemia
Serious Side Effects:
- Bleeding that does not stop
- Blood in urine or stools
- Sudden weakness, severe headache, or collapse
- Signs of a serious allergic reaction
Seek urgent medical attention if you notice heavy or unexplained bleeding.
Some medicines can increase bleeding risk or reduce how Lixiana works.
Tell your prescriber if you take:
- Other anticoagulants or blood thinners.
- Anti-inflammatory painkillers such as acetylsalicylic acid or naproxen.
- Certain antibiotics or antifungal medicines.
- Medicines for heart rhythm problems.
- Epilepsy medicines or St John's Wort.
- Some antidepressants.
Lixiana tablets are often chosen because they:
- Reduce the risk of stroke in atrial fibrillation.
- Prevent blood clots in the veins and lungs.
- Are taken once daily for convenience.
- Do not require routine blood monitoring.
- Fit easily into long-term cardiovascular treatment plans.
Many people find Lixiana provides steady, dependable protection against blood clots.
Getting Lixiana tablets from Pharmacy Planet is simple:
- Complete the online consultation and share details about your heart condition and current medicines.
- A UK-registered prescriber checks whether Lixiana is suitable for you.
- If approved, your prescription is confirmed.
- Your medication is dispensed and delivered discreetly.
Lixiana contains the active substance edoxaban and belongs to a group of medicines called anticoagulants. This medication helps prevent the formation of blood clots. It works by blocking the activity of factor Xa, an important element of blood clotting.
Edoxaban is a highly selective, direct, and reversible inhibitor of FXa, the serine protease found in the last common pathway of the coagulation cascade. Edoxaban inhibits free FXa and prothrombinase activity. Inhibition of FXa in the coagulation cascade reduces thrombin production, prolongs clotting time, and reduces the risk of thrombus formation.
Lixiana is used in adults:
- to prevent the formation of a blood clot in the brain (stroke) and other blood vessels in the body if you have a type of irregular heart rhythm called non-valvular atrial fibrillation and at least one additional risk factor, such as heart failure, having suffered before a stroke or hypertension.
- to treat blood clots in the veins of the legs (deep vein thrombosis) and in the blood vessels of the lungs (pulmonary embolism), and to prevent these blood clots from reappearing in the blood vessels of the legs and/or from the lungs.
Always use this Cardiovascular medication exactly as your doctor or pharmacist has told you. If in doubt, consult your doctor or pharmacist again.
The recommended dose is one 60 mg tablet once a day.
if you have kidney failure, your doctor may reduce the dose to one 30 mg tablet once a day; if you weigh 60 kg or less, the recommended dose is one 30 mg tablet once a day;
If your doctor has prescribed medicines known as P-GP inhibitors: cyclosporine, dronedarone, erythromycin, or ketoconazole, the recommended dose is one 30 mg tablet once a day.
How to take the tablet
Swallow the tablet, preferably with water. Lixiana can be taken with or without food.
Like all medicines, these CV Antiplatelet Tablets can cause side effects, although not everybody gets them.
Like other similar medicines (medicines to reduce blood clotting), Lixiana can cause bleeding, which can be life-threatening. In some cases, the bleeding may not be evident.
If you experience a bleeding episode that does not stop on its own or if you experience signs of excessive bleeding (exceptional weakness, tiredness, paleness, dizziness, headache, or unexplained swelling), see your doctor immediately.
Your doctor will decide whether to keep you under closer observation or to change your treatment.
A general list of possible side effects:
Common (may affect up to 1 in 10 people):
- stomach ache;
- abnormal results in liver values in blood tests;
- bleeding from the skin or under the skin;
- anemia (low levels of red blood cells);
- nasal bleeding;
- vaginal bleeding;
- acne;
- bowel bleeding;
- bleeding from the mouth and / or throat;
- blood in the urine;
- bleeding after injury (puncture);
- stomach bleeding;
- dizziness
- headache;
- Itchiness
Uncommon (may affect up to 1 in 100 people):
- bleeding in the eyes;
- bleeding from a surgical wound after an operation;
- blood in saliva when coughing;
- bleeding in the brain;
- decreased number of platelets in the blood (which can affect clotting);
- allergic reaction;
- urticaria
Rare (may affect up to 1 in 1,000 people):
- bleeding in the muscles;
- joint bleeding;
- bleeding in the abdomen;
- bleeding in the heart;
- bleeding inside the skull;
- bleeding after surgery;
- allergic shock;
- swelling of any part of the body due to the allergic reaction.
warnings and precautions
Edoxaban 15 mg is not indicated as monotherapy as it may lead to decreased efficacy. It is only indicated in the process of switching from edoxaban 30 mg to AVK, together with an appropriate dose of AVK.
Bleeding risk
Edoxaban increases the risk of bleeding and can cause serious life-threatening bleeding. Like other anticoagulants, edoxaban is recommended to be used with caution in patients with an increased risk of bleeding. Edoxaban administration should be discontinued if severe bleeding occurs.
Mucosal bleeding (eg, epistaxis, gastrointestinal, genitourinary) and anemia were observed more frequently in patients receiving long-term edoxaban compared to those receiving AVK treatment. Therefore, in addition to adequate clinical follow-up, hemoglobin and hematocrit measurements could be useful to detect hidden bleeding when considered appropriate.
Several subgroups of patients, as explained below, are at increased risk of bleeding. These patients should be carefully monitored for signs and symptoms of bleeding complications and anemia after initiation of treatment. Any unexplained decrease in hemoglobin levels or blood pressure will require finding a bleeding area.
You can buy Lixiana Tablets online through one of the UK’s leading online pharmacies, Pharmacy Planet. It's easy and convenient. You will need to fill out a short assessment and the item will be delivered directly to your door. If you want to buy this CV Antiplatelet medication online, use Pharmacy Planet, a UK pharmacy you can trust.

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Review By
HARMINDER ‘HARMY’ KAUR
Last Updated On : Mar 13 2026
BSc(hons) Pharmacy
GPhC Number: 2061107

Authored By
GURDEV SEHMI
Last Reviewed On : Mar 23 2026
BSc Pharm, MRPharmS, Independent Prescriber, Superintendent Pharmacist, Clinical Lead
GPhC Number: 2050925








