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Desmopressin Tablets

This medicine is used for the treatment of diabetes insipidus, hemophilia, and nocturnal enuresis and, despite being an analogue of vasopressin, it does not act on V1 receptors, responsible for the vasoconstrictor action, therefore its effect on the vessels blood is practically negligible. Divide the tablets in half or swallow them whole. Do not take Desmopressin with food as the effect of the tablets may be reduced. During treatment with Desmopressin, you should regularly check your body weight, the level of sodium in your blood and/or blood pressure.

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Desmopressin Tablets
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Starts at £63.00
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Price Comparison

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PackPrice (£)
Desmopressin Tablets100mcg180 tablets195.00
Desmopressin Tablets100mcg270 tablets287.00
Desmopressin Tablets100mcg90 Tablets109.00
Desmopressin Tablets200mcg30 Tablets63.00
Desmopressin Tablets200mcg60 Tablets111.00
Desmopressin Tablets200mcg90 Tablets164.00
DDAVP Tablets100mcg180 tablets195.00
DDAVP Tablets100mcg270 tablets187.00
DDAVP Tablets100mcg90 Tablets109.00
DDAVP Tablets200mcg180 tablets245.00
DDAVP Tablets200mcg270 tablets355.00
DDAVP Tablets200mcg90 Tablets137.00
Desmotabs200mcg30 Tablets68.00
Desmotabs200mcg60 Tablets122.00
Desmotabs200mcg90 Tablets181.00

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Desmopressin Tablets for Bedwetting Treatment and Night-Time Urination Control

Desmopressin tablets are used to treat conditions linked to excessive urine production, including bedwetting (nocturnal enuresis) in children over 5 years old and frequent night-time urination (nocturia) in adults. The medicine contains desmopressin, a synthetic version of the body's natural antidiuretic hormone, which regulates how much urine the kidneys produce during the night.

Many people experience disrupted sleep due to repeated trips to the toilet or bedwetting episodes. Desmopressin tablets reduce urine volume overnight, allowing the bladder to stay comfortably full until morning. This improves night-time urination control and restores more settled sleep routines. You can order Desmopressin tablets online from Pharmacy Planet following a short and free online consultation.

What Are Desmopressin Tablets?

Desmopressin tablets contain desmopressin acetate, an antidiuretic hormone analogue. Unlike natural vasopressin, desmopressin does not act on blood vessels, so its effect on blood pressure and circulation is minimal at therapeutic doses. Desmopressin tablets are prescribed for conditions where the body produces too much urine, particularly during the night.

Common uses of Desmopressin tablets include:

  • Bedwetting treatment for children over 5 years old with nocturnal enuresis.
  • Night-time urination control in adults with nocturia.
  • Central diabetes insipidus, a condition causing excessive thirst and urine production.

How Do Desmopressin Tablets Work?

Desmopressin works by mimicking the body's antidiuretic hormone (ADH), which controls water regulation in the kidneys. At night, some people do not release enough ADH, leading to excess urine production while asleep. Desmopressin tablets increase water reabsorption in the kidneys and reduce urine volume for up to 6 to 14 hours. This action prevents the bladder from filling too quickly overnight and reduces bedwetting episodes and night-time bathroom visits. By restoring normal night-time urine control, Desmopressin tablets improve sleep quality and daily confidence.

How to Use Desmopressin Tablets

Always take Desmopressin tablets exactly as prescribed by your pharmacist.

Important Guidance for Use:

  • Swallow the tablet whole or divide it in half as advised.
  • Do not take Desmopressin tablets with food, as food reduces absorption.
  • Take the dose at bedtime unless otherwise directed.
  • Limit fluid intake from one hour before taking the tablet until the following morning.
  • Monitor body weight and attend blood tests if requested by your prescriber.

Nocturnal Enuresis (Bedwetting):

  • Children over 5 years: 200 micrograms (0.2 mg) at bedtime; may be increased to 400 micrograms (0.4 mg) if needed.
  • Treatment is reviewed every three months with a short break to reassess need.

Nocturia (Frequent Night-time Urination):

  • Adults: 100 micrograms (0.1 mg) at bedtime; may be increased gradually up to 400 micrograms (0.4 mg).
  • Treatment should be stopped if symptoms do not improve after four weeks.

Central Diabetes Insipidus:

  • Adults and children: 100 micrograms (0.1 mg) three times daily. Dosage adjustments are made based on response.

Who Can Use Desmopressin Tablets?

Desmopressin tablets may be suitable for:

  • Children over 5 years old with persistent bedwetting.
  • Adults with nocturnal enuresis or night-time urination control problems.
  • Patients diagnosed with central diabetes insipidus.

Desmopressin tablets are not suitable for:

  • Children under 5 years of age.
  • Adults over 65 years for nocturia treatment.
  • People with low blood sodium levels.
  • People with moderate to severe kidney disease.
  • Anyone allergic to desmopressin or tablet ingredients.

During treatment, restrict fluids as advised, follow monitoring instructions carefully, and ensure treatment is reviewed every 3 months. Parents and carers should closely supervise fluid intake in children.

Possible Side Effects of Desmopressin Tablets

Like all medicines, Desmopressin tablets can cause side effects, although not everyone experiences them.

Very Common Side Effects:

  • Headache

Common Side Effects:

  • Dry mouth, abdominal pain, feeling sick, dizziness, swelling of arms or legs, weight gain, increased urinary frequency

Very Rare Side Effects:

  • Emotional changes in children, allergic reactions

Serious Reactions Requiring Urgent Medical Attention:

  • Severe headache with nausea, unexplained rapid weight gain, swelling of the face/lips/tongue/throat, difficulty breathing or swallowing, seizures or loss of consciousness

Why Choose Desmopressin Tablets for Enuresis Therapy?

Desmopressin tablets are widely used because they reduce urine volume overnight, improve night-time urination control, provide effective bedwetting relief, support better sleep and daily confidence, and offer a proven ADH medication in tablet form.

Buy Desmopressin Tablets Online from Pharmacy Planet

You can buy Desmopressin tablets online from Pharmacy Planet, following some simple steps.

  1. Complete a short online consultation about your symptoms and health.
  2. One of our UK prescribers reviews your information.
  3. If approved, your Desmopressin tablets are dispensed and delivered discreetly to your home.
Desmopressin Tablets

Desmopressin tablets contain a synthetic version of the body's natural antidiuretic hormone, reducing urine volume overnight. Used to treat bedwetting in children over 5 and frequent night-time urination (nocturia) in adults, improving sleep and night-time urination control.

An antidiuretic hormone analogue (desmopressin acetate) prescribed when the body produces too much urine, particularly at night. Used for bedwetting treatment (children over 5), night-time urination control in adults, and central diabetes insipidus.

Mimics the body's ADH to increase water reabsorption in the kidneys and reduce urine volume for up to 6–14 hours. Prevents the bladder from filling too quickly overnight, reducing bedwetting and night-time bathroom visits.

Take at bedtime without food (food reduces absorption). Limit fluid intake from 1 hour before until the following morning. Bedwetting (children over 5): 200–400 micrograms at bedtime. Nocturia (adults): 100–400 micrograms at bedtime. Central DI: 100 micrograms three times daily. Reviewed every 3 months.

Suitable for children over 5 with persistent bedwetting, adults with nocturia or nocturnal enuresis, and patients with central diabetes insipidus.

Not suitable for under 5s, adults over 65 for nocturia, people with low blood sodium, moderate-severe kidney disease, or allergy to desmopressin.

Very Common: Headache

Common: Dry mouth, abdominal pain, nausea, dizziness, arm/leg swelling, weight gain, increased urinary frequency

Very Rare: Emotional changes in children, allergic reactions

Seek urgent help for: Severe headache with nausea, rapid unexplained weight gain, face/lip/tongue/throat swelling, breathing difficulty, seizures, or loss of consciousness

Desmopressin tablets reduce overnight urine volume, improve night-time urination control, provide effective bedwetting relief, support better sleep and confidence, and offer a proven ADH treatment in tablet form.

You can buy Desmopressin tablets online from Pharmacy Planet simply and safely.

  1. Complete a short online consultation about your symptoms and health.
  2. One of our UK prescribers reviews your information.
  3. If approved, your Desmopressin tablets are dispensed and delivered discreetly to your home.
Frequently Asked Questions

Desmopressin tablets usually start working from the first night. Many children and adults notice fewer wet nights or no bedwetting at all within the first few doses, as urine production at night is reduced straight away.

Desmopressin tablets control bedwetting while you are taking them, but they do not permanently cure the condition. Bedwetting often improves naturally over time, and treatment is reviewed regularly to see if it is still needed.

Yes, Desmopressin tablets are safe for nightly use when taken exactly as prescribed. Fluid restriction is important, and regular reviews are needed to reduce the risk of water retention or low sodium levels.

Desmopressin reduces urine production and thirst. Drinking too much fluid can cause water to build up in the body, which may lower sodium levels. Limiting fluids keeps treatment safe and effective.

Yes, Desmopressin tablets are prescribed for adults with nocturia caused by excess urine production at night. Treatment should be started and monitored by a specialist, especially if doses are adjusted.

If bedwetting continues, your prescriber may adjust the dose or review whether the medicine is suitable. Treatment is usually reassessed every three months, with short breaks to check ongoing need.

If you miss a dose, skip it and take your next dose at the usual time the following night. Do not take a double dose to make up for a missed tablet.

Desmopressin tablets work faster and are often preferred for immediate control, such as sleepovers or school trips. Bedwetting alarms focus on long-term training. Some people use both approaches depending on circumstances.

Yes, you can buy Desmopressin tablets online from Pharmacy Planet after completing a short online consultation. A UK prescriber reviews your information before approving treatment, and delivery is discreet.

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Review By

HARMINDER ‘HARMY’ KAUR

Last Updated On : Mar 13 2026

BSc(hons) Pharmacy

GPhC Number: 2061107

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Authored By

GURDEV SEHMI

Last Reviewed On : Mar 23 2026

BSc Pharm, MRPharmS, Independent Prescriber, Superintendent Pharmacist, Clinical Lead

GPhC Number: 2050925