Carbocisteine

Carbocisteine is a drug, generally without a prescription, with a mucolytic action. Carbocisteine fluidizes bronchial secretions, made more viscous by infection, facilitating and increasing expectations with effective release of the bronchi. As a consequence of this, Carbocisteine-based drugs are therefore used in asthma treatment and for the treatment of other respiratory diseases that involve the formation of dense and viscous secretions, difficult to expect, as is the case of fatty coughs due to cooling diseases or acute bronchitis.

Carbocisteine is a molecule with mucolytic activity, chemically related to acetylcysteine, used as a cough treatment drug with the presence of mucus. Obtained by alkylation of cysteine with chloroacetic acid, it has the ability to thin the mucus present in the airways and is therefore also used to reduce the symptoms of chronic obstructive pulmonary disease and bronchiectasis. The active substance is carbocisteine. Each capsule contains 375 mg of carbocisteine. The other ingredients are: Capsule Contents: mannitol; maize starch; croscarmellose sodium; sodium lauryl sulfate, grade K12; colloidal anhydrous silica and magnesium stearate. Capsule Shell: gelatine; red iron oxide E172; titanium dioxide E171 and yellow iron oxide E172.

Carbocisteine works by modifying the synthesis of mucus glycoproteins, decreasing the production of fucomucines and increasing that of sialoglycoproteins that have a lower pH. These proteins allow the bronchial cilia to do their job better. According to recent studies, sialomucins could have a certain anti-inflammatory effect on the mucosa, so it also has some efficacy in otitis and sinusitis.

The benefits of the Carbocisteine capsules uses include restoring the synthesis of glycoproteins, rebalancing the biosynthetic capacity of the cell; Reducing the synthesis of sialoproteins whose presence is crucial in maintaining the rheological properties of mucus. It Increases the secretion of chlorine, attracting water and thus making the mucus more fluid. It protects the cell from oxidative damage induced by reactive oxygen species, inducing the synthesis of IgA and other mediators capable of increasing the barrier function of the respiratory mucosa. Following good intestinal absorption, Carbocysteine is rapidly concentrated at the lung level and subsequently eliminated mainly through the urine.

Always use this medicine exactly as described in this leaflet or as your doctor or pharmacist has told you. The recommended dose is:

Adults and adolescents from 12 years:

15 ml of oral solution every 8 hours, which means a daily maximum of 45 ml of oral solution (2.25 g of carbocysteine).

Do not take more than 2.25 g per day, divided into 3 doses. Once you see improvement, you can reduce it to 1.5 g in 24 hours spread over 2 shots.

Use in children.

Children under the age of 12 cannot take this medicine.

This medicine is taken orally. Measure the amount of medicine you have to take with the measuring cup contained in the container. It is preferable that the medication be taken before a meal. It is recommended to drink a glass of water after each dose and plenty of liquid throughout the day. If it worsens, or does not improve after 5 days of treatment, or fever, rash, persistent headache, or sore throat occurs, you should consult your doctor.

Like all medicines, cinfamucol carbocysteine can have side effects, although not everyone gets them. During the period of carbocisteine use, the following side effects have been observed, the frequency of which cannot be established with precision. Carbocisteine capsule side effects include:

Uncommon side effects (less than 1 in 100 patients):

• Gastrointestinal disorders such as: nausea, vomiting, diarrhea or dyspepsia (gastrointestinal upset). In some cases it may be useful to reduce the administered dose.
• Bleeding in the stomach or intestine
• Headache
• Itching and skin rashes have been observed rarely.

Reporting of adverse effects: If you experience any type of side effect, consult your doctor or pharmacist.

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