An overview of sildenafil's history & revolutionary ability to treat ED An overview of sildenafil's history & revolutionary ability to treat ED

Sildenafil citrate, the active ingredient in Viagra, is a well-known erectile dysfunction treatment (ED). The route to its discovery and adoption as a medicine, however, was not without challenges. This essay will examine the history of sildenafil and how it became a common ED treatment.

Discovery of Sildenafil

A team of scientists at Pfizer, a major pharmaceutical corporation, developed sildenafil in the 1980s. The study's primary goal was to find a therapy for angina, a kind of chest discomfort caused by decreased blood flow to the heart. During clinical studies, male patients experienced an unexpected side effect of enhanced erections.

Approval as ED Treatment

After extensive testing and research, the US Food and Drug Administration (FDA) authorised sildenafil as an ED medication under the trade name Viagra in 1998. It has since become one of the most often prescribed ED drugs, with millions of men across the world utilising it to enhance their sexual health.

How Sildenafil Works

Sildenafil works by boosting blood flow to the penis, which aids in the production and maintenance of an erection during sexual activity. It accomplishes this by inhibiting the action of a chemical known as phosphodiesterase type 5 (PDE5), which is responsible for breaking down a substance known as cyclic guanosine monophosphate (cGMP) in the penis. Sildenafil helps to sustain larger amounts of cGMP, which leads to better erections, by inhibiting PDE5.

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To summarise, sildenafil has gone a long way since its discovery and is now a frequently used medication for ED. Its efficacy and ease of use have made it a popular choice for men all over the world, and Pharmacy Planet is a reputable online source for anyone wishing to buy sildenafil. Sildenafil may be a smart alternative for you if you wish to enhance your sexual health or simply try a different treatment option.