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Colazide Balsalazide is a prodrug of 5-aminosalicylic acid (also known as mesalazine) that hydrolyzes in the intestine, causing the active drug that has anti-inflammatory properties. Colazide Balsalazide comes as a capsule that is to be taken orally. It is generally taken 3 times a day. Carefully follow the directions on the medicine label and ask your doctor or pharmacist anything you don't understand. Use the medication exactly as directed. Do not use more or less than the indicated dose or more often than prescribed by your doctor. Colazide Balsalazide is generally taken for 8 weeks but can be taken for up to 12. Continue taking the medication even if you feel better, and do not stop taking it without first talking to your doctor.

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Colazide750mg130 capsules88.00
Colazide750mg260 capsules152.00
Colazide750mg390 capsules234.00

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Colazide Balsalazide is a prodrug of 5-aminosalicylic acid (also known as mesalazine) that hydrolyzes in the intestine, causing the active drug that has anti-inflammatory properties. Colazide Balsalazide comes as a capsule that is to be taken orally. It is generally taken 3 times a day.

Frequently Asked Questions

Colazide Balsalazide is a drug for known its gastrointestinal Treatment capabilities, It does this releasing a substance, called mesalamine, which acts as an intestinal anti-inflammatory with local action on the internal lining (mucous membrane) of the large intestine (colon). Ulcerative colitis is a disease characterized by inflammation of the mucous membranes of the large intestine (colon) and rectum. Colazide Balsalazide works locally by reducing inflammation (treatment in the active phase). After symptoms disappear, Balzide can be used to prevent further flare-ups of symptoms (treatment in the maintenance phase)

Colazide Balsalazide reaches the colon intact, where it is cleaved by bacterial azo reduction to release equimolar amounts of mesalamine (5-aminosalicylic acid), which is the therapeutically active portion of the molecule, and the carrier residue 4-aminobenzoyl-β-alanine. This carried rest only minimally absorbs and is largely inert.

The mechanism of action of 5-ASA is unknown, but it appears that this action is local, in the mucosa of the colon. The production of the arachidonic acid metabolites by the mucosa of the colon, both through the cyclooxygenase pathway, that is, the prostanoids, and through the lipoxygenase pathways, that is, leukotrienes and hydroxyeicosatetraenoic acids, is found increased in patients with chronic inflammatory bowel disease. 5-ASA decreases inflammation by blocking the production of arachidonic acid metabolites in the colon.

Colazide Balsalazide capsules are used to treat ulcerative colitis (a disorder that causes inflammation and ulcers in the lining of the colon [large intestine] and rectum). Balsalazide is an anti-inflammatory medicine. In the body, it is converted to mesalamine and works by reducing intestinal inflammation, diarrhea, rectal bleeding, and stomach pain

The medication comes as Colazide Capsules that are taken orally. It is generally taken 3 times a day. Carefully follow the directions on the medicine label and ask your doctor or pharmacist anything you don't understand. Use the medication exactly as directed. Do not use more or less than the indicated dose or more often than prescribed by your doctor.

Balsalazide is generally taken for 8 weeks but can be taken for up to 12. Continue taking the medication even if you feel better, and do not stop taking it without first talking to your doctor.

Treatment of mild to moderately active ulcerative colitis in patients 5 years of age and older. Adults:

The usual dose is 2.25 mg of balsalazide to be taken 3 times a day (6.75 g per day) for up to 8 weeks. Some adult patients require treatment of up to 12 weeks.

Children 5-17 years:

2.25 mg of balsalazide 3 times a day (6.75 g per day) for up to 8 weeks or 750 mg of balsalazide 3 times a day (2.25 g per day) for a maximum of 8 weeks.

The use of balsalazide in the pediatric population for more than 8 weeks has not been evaluated.

Medicines and their possible side effects can affect individuals in different ways. Just because a side effect is listed here does not mean that all women using this medication will experience any. The list of the Colazide side effects is the following:

  • headache (headache)
  • abdominal pain
  • Stomach ache
  • diarrhea
  • vomiting
  • joint pain
  • difficulty falling asleep and staying asleep
  • fatigue
  • gases
  • runny nose
  • muscle or back pain
  • cough
  • loss of appetite
  • urinary tract infection
  • constipation (constipation)
  • dry mouth}

If you experience any of the following symptoms, call your doctor immediately:

  • yellowing of the skin or eyes
  • dark urine
  • abdominal cramps or inflammation
  • increased diarrhea
  • rectal bleeding
  • fever, sore throat, or flu-like symptoms

You can buy Colazide balsalazide online through one of the UK’s leading online pharmacies, Pharmacy Planet. It's easy and convenient. You will need to fill out a short assessment and the item will be delivered directly to your door. If you want to buy Colazide capsules online, use Pharmacy Planet, a UK pharmacy you can trust.

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Review By

HARMINDER ‘HARMY’ KAUR

Last Updated On : Mar 13 2026

BSc(hons) Pharmacy

GPhC Number: 2061107

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Authored By

GURDEV SEHMI

Last Reviewed On : Mar 23 2026

BSc Pharm, MRPharmS, Independent Prescriber, Superintendent Pharmacist, Clinical Lead

GPhC Number: 2050925